Multiple Sequence Alignment:
hnRNP A/B Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330        )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |        
hnRNP A/B human MSEAGEEQPMETTGATENGHEAVPEA------SRGRGWTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTskkDLkDYFTkFGEVVDCtIkMDPNTGRSRGFGFILFkDAASVEkVLDQkEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPESPTEEKIREYFGEFGEIEAIELPMDPkLNKRRGFVFITFKEEEPVKKVLEKkFHTVSGSkCEIkVAQPkEVyQQQQyGsGGrGNrNrGNrGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGyyGYGPGYDYSQGStNyGKSQrrGGHQNNykPy
hnRNP A/B iso2 human MSEAGEEQPMETTGATENGHEAVPEGE-----SPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKkIFVGGLNPEA-TEEkIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY
hnRNP A/B iso3 human MsEAGEEQPMETTGATENGHEAVPEGE-----SPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKkIFVGGLNPEA-TEEkIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVyQQQQYGSGGRGNRNrGNrGsGGGGGGGGQ-----------------------------------------------GStNyGksQRRGGHQNNYKPY
hnRNP A/B mouse MSDAAEEQPMETTGATENGHEAAPEGEAPVEPSAAAAAPAASAGSGGGTTTAPSGNQNGAEGDQINASKNEEDAGkMFVGGLSWDTSkkDLkDYFTkFGEVVDCTIkMDPNTGRSRGFGFILFkDSSSVEkVLDQkEHRLDGRVIDPKKAMAMKKDPVKkIFVGGLNPEA-TEEkIREYFGQFGEIEAIELPIDPkLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSkCEIKVAQPkEVYQQQQyGsGGrGNrNrGNrGsG-----GGQ-----------------------------------------------GsTNYGKSQrrGGHQNNYkPY
hnRNP A/B iso2 mouse MSDAAEEQPMETTGATENGHEAAPEGEAPVEPSAAAAAPAASAGSGG-------GNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDSSSVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEA-TEEKIREYFGQFGEIEAIELPIDPKLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNrGNrGSG-----GGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDySPyGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY
hnRNP A/B rat MSDAAEEQPMETTGATENGHEAAPEGEAPVEPSPGSG-PATPAGSVGGTTAAPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLkDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDSSSVEkVLDQKEHRLDGRVIDPKKAMAMkKDPVKKIFVGGLNPEA-TEEkIREYFGQFGEIEAIELPIDPkLNKRRGFVFITFKEEDPVKKVLEKkFHTVSGSkCEIkVAQPkEVYQQQQYGSGGrGNrNRGNRGSG-----GGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRrGGHQNNYkPY
  **:*:*****************:**::.....*::::.::::**::*:::::::***********************************************************************::******************************************: **********:**********:******************:**************************************************.....***:::::::::::::::::::::::::::::::::::::::::::::::*********************
Consensus MSDAAEEQPMETTGATENGHEAAPEGEAPVEPSPAAAAPAAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEA-TEEKIREYFGQFGEIEAIELPIDPKLNKRRGFVFITFKEEDPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGYYGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.