Multiple Sequence Alignment:
SPR	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 )
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SPR human	-MEGGLGRAVCLLTGAsRGFGRtLAPLLASLLsPGsVLVLsARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGsLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDsPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETsVDPDMRKGLQELkAKGkLVDCKVSAQkLLsLLEk K247-ac K247-ub DEFKSGAHVDFYDK
SPR mouse	MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLk K52-ac K52-ub K52-sc EELGAQQPDLk K63-ac K63-sc VVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNyWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGkAARDMLYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLk sDGALVDCGTSAQKLLGLLQKDTFQSGAHVDFYD-
SPR rat	MEGGRLGCAVCVLTGASRGFGRALAPQLAGLLsPGSVLLLSARSDsMLRQLKEELCTQQPGLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAVEEPSVRVLsYAPGPLDTNMQQLARETsMDPELRSRLQKLNsEGELVDCGTSAQKLLSLLQRDTFQSGAHVDFYDI
	:::::::*******::.****:::::::*::::::::.:::**::::*::****::******::*****::.::::***************::::.:::*********::*********:::*:***::*****.:::.:::.:*::**:::::*********.
Consensus	MEAGGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVLLLSARSDSMLRQLKEELGAQQPGLRVVLAAADLGTEAGVQQLLSAVRELPRPEGLQRLLLINNAGTLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAAEEPSVRVLSYAPGPLDTDMQQLARETSKDPELRSRLQKLKSDGALVDCGTSAQKLLSLLQKDTFQSGAHVDFYDI

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.