Multiple Sequence Alignment:
HADHSC Download MSA
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HADHSC human -----------------------------------------------------------MAFVTRQFMRSVsSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKkGIEEsLrkVAKkkFAENLkAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVkNELFkRLDkFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMkLVEVIkTPMTSQktFEsLVDFskALGkHPVSCkDtPGFIVNRLLVPyLMEAIRLyER-----------------GDASkEDIDTAMkLGAGYPMGPFELLDyVGLDttKFIVDGWHEMDAENPLHQPsPSLNKLVAENkFGkKTGEGFYkyK
HADHSC iso2 human MGRAGLEAPPPPCGVTGTPGARGLQGRVGPRPQSLAFRGCLPRASSLPGSPRCRRRCHTMAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERDFQTCGDSNSGLGFSLKGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
HADHSC iso3 human -----------------------------------------------------------MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERDFQTCGDSNSGLGFSLKGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
HADHSC mouse -----------------------------------------------------------MAFVTRQFLRSMssSSSASAAAKKILIKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKkGIEEsLkRMAKkkFTENPkAGDEFVEKTLSCLSTSTDAASVVHSTDLVVEAIVENLkLKNELFQRLDkFAAEHTIFASNTSSLQITNIANATTRQDRFAGLHFFNPVPMMkLVEVIktPMTSQkTFEsLVDFCkTLGKHPVSCkDTPGFIVNRLLVPYLIEAVRLHER-----------------GDAskEDIDTAMkLGAGYPMGPFELLDYVGLDTTKFILDGWHEMEPENPLFQPSPSMNNLVAQkkLGKKTGEGFYkYk
HADHSC rat -----------------------------------------------------------MAFVTRQFVRSMsSSSSASAAAKKILIKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKkGIEESLkRMAKKkFTENPkAADEFVEKTLSSLSTSTDAASVVHSTDLVVEAIVENLkLKNELFQRLDkFAAEHTIFASNTSSLQITNIANATTRQDRFAGLHFFNPVPMMkLVEVIkTPMTSQkTFESLVDFCkTLGKHPVSCkDTPGFIVNRLLVPYLIEAIRLHER-----------------GDASkEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFILDGWHEMDPENPLFQPSPSMNNLVAQKKLGKKTGEGFYKYK
                                                             ********:**:****:***:****::***********************************************:::*****:**:**:*********:::************************:*****:**********************:*********************:***********************:*:************************:**:**:**.................*************************************:******::****:*****:*:***::*:************
Consensus -----------------------------------------------------------MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER-----------------GDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.