(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500    )
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SHE human	MQWSPTPGASACLGWASSLACSTAPTLLGRAGRGPLMAAKWFKEFPLNLktVSERAKPGGGGGkLRKNsEAGGAGPGPGKGRKNsAAELGSGRAGVGP-KDSRLSRDSLQGLIQAAAGkGRKNsR----AtEEEPHRGAT-KSSGCSTYINRLIKVDTQEKNGKSNYP--SsssssSSSsSSASSSPssLGPELDKGKIIKQQETVIILEDyADPYDAKRTKGQRDAERVGENDGyMEPYDAQQMITEIRRRGsKDPLVKALQLLDSPCEPADGGLKSETLAKRRSSKDLLGKPPQLyDTPYEPAEGGPR-AEGKARPPDsRLPENDERPAAEYEQPWEWKKEQIVRALsVQFEGAERPSFREETVRQHHRQKSWTQKILKPALsDHSEGEKVDPGLPLEKQPWYHGAISRAEAESRLQPCKEAGYLVRNSESGNSRYSIALKTSQGCVHIIVAQTKDNKyTLNQTSAVFDSIPEVVHyySNEKLPFKGAEHMTLLYPVHSKLH
SHE mouse	MRRPPAPGAPRCLSWASSLFCSAASTLPG-----PLMAAKWFKEFPLTLKTASERARPGGAGGKPRKNsETGGAAPTPGKGRKNsAAELGASKASSGPPkDSRLsRDsLQGLIQAAAGkGRKNSRVTATATEEEPHRGAVTKSAGCSTYISRLIKVDTQEKNGKSAYPGGGSTSSSSSSSSSASSSPSSLGPELDKAKIMRQQDTVIILEDyADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGsKDPLVKALQLLDGPSEPGE-TVKVEATAKRRSsKDLLGKPPQLyDTPYEPSEGGQRVAEVKTRPADSRLPEEDDRPAAEYEQPWEWKREQIARALsVQFEGSDRPPGREDAGRPHHWQK-----TLKPTLsDHGDGEKVDPGLALEKQPWYHGSISRAEAESRLQPCKEAAYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNAKLPFKGAEHMTLLHPVH-KLH
SHE rat	MRRPPAPGAPWCLGWASSLVCSAASTLPG-----PLMAAKWFKEFPLTLKTASERARPGGAGGKPRKNSETGSAAPTPGKGRKNsAAELGGSRTGSGPPKDSRLSRDSLQGLIQAAAGKGRKNSRVTTTATEEEPHRGAVAKSAGCSTYISRLIKVDTQEKNGKSIYPGGGSTSSSSSSSSSASSSPSSLGPELDKTKIMRQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGsKDPLVKALQLLDGPCEPGE-TMKVEATAKRRSSKDLLGKPPQLYDTPYEPSEGDLRAAEVKARPADGRLPEEDDRPAAEYEQPWEWKREQIARALSVQFEGSDRSPGREEAGRPQHWQK-----TLKPTLsDHGDGEKVDPGLALEKQPWYHGSISRAEAESRLQPCKEAGYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDSRYTLNQTSAVFDSIPEVVHYYSTAKLPFKGAEHMTLLHPVH-KLH
	*:::*:***::**:*****:**:*:**:*.....*************:***:****:***:***:*****:*:*:*:*************::::::**:**************************::.:**********:.**:******:**************:**:::*:***********************:**::**:**************************************************************:*:**::.:.*:*::***********************:**:.*.**:*:**:*:****:*:*************:***:*********::*:::**:::*::*:**.....:***:****::********:*********:****************:***********:*********************::*********************::*************:***.***
Consensus	MRRPPAPGAPACLGWASSLACSAASTLPG-----PLMAAKWFKEFPLTLKTASERARPGGAGGKPRKNSETGGAAPTPGKGRKNSAAELGASRAGSGPPKDSRLSRDSLQGLIQAAAGKGRKNSRVTATATEEEPHRGAVAKSAGCSTYISRLIKVDTQEKNGKSAYPGGGSTSSSSSSSSSASSSPSSLGPELDKAKIMRQQDTVIILEDYADPYDAKRTKGQRDAERVGENDGYMEPYDAQQMITEIRRRGSKDPLVKALQLLDGPCEPGE-TLKVEATAKRRSSKDLLGKPPQLYDTPYEPSEGGQRAAEVKARPADSRLPEEDDRPAAEYEQPWEWKREQIARALSVQFEGSDRPPGREEAGRPHHWQK-----TLKPTLSDHGDGEKVDPGLALEKQPWYHGSISRAEAESRLQPCKEAGYLVRNSESGNSKYSIALKTSQGCVHIIVAQTKDNKYTLNQTSAVFDSIPEVVHYYSNAKLPFKGAEHMTLLHPVH-KLH