Multiple Sequence Alignment:
HIBCH	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 )
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HIBCH human	MGQREMWRLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEkKGCTGVITLNRPKFLNALTLNMIRQIYPQLkKWEQDPETFLIIIKGAGGk K92-ac K92-ub K92-sc AFCAGGDIRVISEAEKAKQkIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLkGRDVYRAGIATHFVDSEKLAMLEEDLLALk sPSkENIASVLENyHTESkIDRDKsFILEEHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINkMSPTSLKITLRQLMEGSSKTLQEVLTMEyRLSQACMRGHDFHEGVRAVLIDk K353-ac K353-sc DQsPKWKPADLKEVTEEDLNNHFKSLGSSDLKF
HIBCH mouse	MGQPYAWRLLSRVSSFRRASVILQHLRMSMHTEAA-EVLLERRGCGGVITLNRPk K54-ac K54-sc FLNALSLNMIRQIYPQLkTWEQDPDTFLIIIk K86-ac K86-sc GAGGkAFCAGGDIk K100-ac K100-sc ALSEAkKARQNLTQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTGYRLKGRDVHRAGIATHFVDSEkLRVLEEELLALkSPSAEDVAGVLESYHAkSkMDQDkSIIFEEHMDKINSCFSANTVEQIIENLRQDGSPFAIEQMk K296-ac K296-sc VINk K300-ac K300-sc MSPTSLKITLRQLMEGSSKTLQEVLIMEYRITQACMEGHDFHEGVRAVLIDk K352-ac K352-sc DQTPkWk K359-ac K359-sc PANLk K364-ac K364-sc DVTDEDLNSYFkSLGSSDLKF
HIBCH rat	MGQQFVWRLQSRFSSIRRASVILQHLRMSKHTETA-EVLLERRGCAGVITLNRPkLLNALSLNMIRQIYPQLk kWERDPDTFLIIIKGAGGkAFCAGGDIkALSEAKKAGQTLSQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVHRAGIATHFVDSEkLHVLEEELLALKSPSAEDVAGVLESYHAKSKMGQDKSIIFEEHMDKINSCFSANTVEQILENLRQDGSPFAMEQIkVINkMSPTSLKITLRQLMEGSTKTLQEVLTMEYRLTQACMEGHDFHEGVRAVLIDkDQTPKWkPADLkDVTDEDLNSYFkSLGSRDLKF
	*..:.:::::::::*:::.**:::*******::********:::****************::::..:::::***:::******:*****************::***:************************:***:**********:::******::::::::::::****************::*::..******************:***::::*************:**:::::**:**
Consensus	MGQREAWRLQSRFSSFRRASVILQHLRMSKHTEAA-EVLLERRGCAGVITLNRPKFLNALSLNMIRQIYPQLKKWEQDPDTFLIIIKGAGGKAFCAGGDIKALSEAKKARQNLAQDLFREEYILNNAIASCQKPYVALIDGITMGGGVGLSVHGQFRVATERSLFAMPETGIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVHRAGIATHFVDSEKLAVLEEELLALKSPSAEDVAGVLESYHAKSKMDQDKSIIFEEHMDKINSCFSANTVEQIIENLRQDGSPFAIEQIKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLTQACMEGHDFHEGVRAVLIDKDQTPKWKPADLKDVTDEDLNSYFKSLGSSDLKF

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.