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DENND2A human	-----MDMFSLDMIISDPAAE-----ASRAGKKQLRGVQNPCPSARARPRHKSLNIKDKISEWEGKKEVPTPAPSRRADGQEDyLPSSTVERRSsDGVRTQVTEAKNGMRPGTESTEKERNKGAVNVGGQDPEPGQDLSQPEREVDPSWGRGREPRLGKLRFQNDPLSVLKQVKKLEQALKDGsAGLDPQLPGtCYSPHCPPDKAEAGSTLPENLGGGSGSEVSQRVHPSDLEGREPTPELVEDRKGSCRRPWDRsLENVYRGSEGSPTKPFINPLPKPRRTFKHAGEGDKDGKPGIGFRKEKRNLPPLPSLPP--PPLPSSPPPSSVNRRLWTGRQKSSADHRKsYEFEDLLQSSSESSRVDWyAQTKLGLtRtLsEENVYEDILDPPMKENPyEDIELHGRCLGKKCVLNFPAsPTssIPDTLTKQSLSKPAFFRQNSERRNFKLLDTRKLSRDGTGSPSKISPPSTPSSPDDIFFNLGDPQNGRKKRKIPKLVLRINAIYEVRRGKKRVKRLsQSMESNSGKVTDENSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYPSLARELIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLERSFKFMREAEDQLKAIPQFCFPDAKDWVPVQQFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSRILDEVEKRRGISPALVQPLMRSVMEAPFPALGKTILVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVCVFASLLLERRVIFIADKLSILSKCCHAMVALIYPFAWQHTYIPVLPPAMVDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLVNSRFLRQMDDEDSILPRKLQVALEHILEQRNELACEQDEGPLDGRHGPESSPLNEVVSEAFVRFFVEIVGHYSLFLTSGEREERTLQREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK
DENND2A mouse	MLEARVDMLSSNMIISGPAADLGAKEASRPWKKQLNSVPNSGPSARARAQPQPLSIKDKISKWEGKKEPPASDPARQTDGQEDHLPSCKVERRGsELT-----RTKNGMRLETERLQNDSRARTVCQ-DTEQLPGPRP--IDGQPELSQHRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQMPGTCYSPHCLPDKTEEDLPSLESHE--KGGVLAAGRRAHHLEVREPGPEISEDWKG---------QESVYRGSRWYPPKPFINPVPKPRRTFKHAGEGDKDVSPGISFKKEKRNLPPLPSLPPPPPPLPssPPPTSVNRRLWTGRQRPSADHRKsyEFEDLLQSSSENSRVDWyAQTKLGLtRtLsEENVyEDILDPPMKENPyEDVELHGRCLGKKCVLtFPAsPtssIPDTSTKQSLSKSAFFRQNsERRNLKLLDTRKLsRDGAGsPLRTSPPSTPSSPDDTFFNLGDLQNGRKKKKIPRLVLRINAIYEARRGKKRVKRLsQSTESNSGKVtDENsEsDsDTEEKLKAHSQRLVNVKSRLKQAPRYssLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLEKSFKFMREAEDQLKAIPQFCFPDAKDWAPVQEFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGKTIIVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLSTLSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLINDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVRFFVEIVGHYPLFLTSGE--ERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK
DENND2A rat	MLEARVDMLSSNMIISGPAADLGAKEASRPLKKQLSSVQNPGPSTQARA--QPLSIKDKISKWEGKKEPPASDPARQTDGQEDYLPSCRVERRGsELT-----RTKNGMRLETESLQNDSRTRTMCQ-DAERLPGLRQ--IDGQPEPSQPRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQLPGTCYSPHCLPDKTEEDQPIPESHE--SGVSLASGRRAHHSEVREPGPEISEEWKG---------QENVYRGSRWHPQKPFINPVPKPRRTFKHAGEGDKDGNPGISFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSADHRKsYEFEDLLQSSSENSRVDWYAQTKLGLTRTLsEENVYEDILDPPMKENPYEDVESHGRCLGKKCVLTFPGSPTSSIPDTSTKQSLSKSAFFRQNSERRNFKLLDTRKLSRDGTGSPLRTSPPSTPSSPDDTFFNLGDLQNGRKKKKIPKLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLEKSFKFLREAEDQLKAIPQFCFPDAKDWSPVQEFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRsVMEAPFPALGKTITVKNFLPGSGtEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLSTLSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLINDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVRFFVEIVGHYSLFLTSGE--ERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK
	::::::**:*::****:***::::::***:.****.:*:*::**::**:..::*:******:******:*:::*:*::*****:***:.****:*:::.....::*****::**:::::::::::::.:::.:**.:...:::::::*:.****:::::****:*:****:***:**:************:*********:***:*::.:.:*:::..:*..::::::::::*:***:**::*::**.........:*:*****::.*.******:****************:.***:*:**************::*********:***********::*******************:**************************************:*:***********:**:*********:*******:***********:************:***:::***********:******:******:***:**********:*************:******************************************:**:*:****************************************:****:*********************:***:***************************************************:***********************************.*****************************************:*******************:***************:*************:**********************************:*:******:**********************:***:**:****::******:*:******************:*******..**:****************:*********:*******************************************************
Consensus	MLEARVDMLSSNMIISGPAADLGAKEASRPGKKQLRSVQNPGPSARARARHQPLSIKDKISKWEGKKEPPASDPARQTDGQEDYLPSCRVERRGSELT-----RTKNGMRLETESLQNDSRARTVCQ-DAERLPGQRQ--IDGQPEPSQGRGRELKPSDLRFQSDHLSVLRQVKRLEKALKDGSAGLDPQLPGTCYSPHCLPDKTEEDQPIPESHE--SGGELAAGRRAHHLEVREPGPEISEDWKG---------QENVYRGSRWHPQKPFINPVPKPRRTFKHAGEGDKDGNPGISFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSADHRKSYEFEDLLQSSSENSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDVELHGRCLGKKCVLTFPASPTSSIPDTSTKQSLSKSAFFRQNSERRNFKLLDTRKLSRDGTGSPLRTSPPSTPSSPDDTFFNLGDLQNGRKKKKIPKLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDENSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHKKQAGAAYVPELTQQFPLKLEKSFKFMREAEDQLKAIPQFCFPDAKDWAPVQEFTSETFSFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGISPALVQPLMRSVMEAPFPALGKTIIVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSSLSVRHLVSVFASLLLERRVIFIADKLSTLSKCCHAMVALIYPFSWQHTYIPVLPPAMIDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLINDRFLRQMEDEDSILPRKLQVALEHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVRFFVEIVGHYSLFLTSGE--ERSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKGLFEVRAQEYLETLPSGEHSGVNKFLKGLGNKMKFLHKK