Multiple Sequence Alignment:
TPM2 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280    )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |    
TPM2 human MDAIKKKMQMLkLDKENAIDRAEQAEADkkQAEDRCkQLEEEQQALQkKLKGtEDEVEkysEsVkEAQEKLEQAEkkAtDAEADVAsLNRRIQLVEEELDRAQERLAtALQkLEEAEkAADEsERGMkVIENRAMkDEEkMELQEMQLkEAKHIAEDsDRkyEEVARkLVILEGELERSEERAEVAEsKCGDLEEELkIVTNNLksLEAQADkYSTKEDkyEEEIkLLEEkLkEAEtRAEFAERsVAkLEktIDDLEDEVyAQKMKykAISEELDNALNDItsL
TPM2 iso2 human MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKsLMAsEEEYsTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEktIDDLEETLAsAKEENVEIHQTLDQTLLELNNL
TPM2 mouse MDAIKKkMQMLkLDkENAIDRAEQAEADkkQAEDRCkQLEEEQQALQkKLkGTEDEVEkysESVkDAQEkLEQAEkkATDAEADVAsLNRRIQLVEEELDRAQERLATALQkLEEAEkAADESERGMkVIENRAMkDEEkMELQEMQLkEAkHIAEDSDRkyEEVARkLVILEGELERSEERAEVAESKCGDLEEELkIVTNNLksLEAQADkYStKEDkYEEEIkLLEEkLkEAETRAEFAERSVAkLEktIDDLEDEVyAQkMKYKAISEELDNALNDItsL
TPM2 iso2 mouse MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALksLIASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKtIDDLEETLASAKEENVEIHQTLDQTLLELNNL
TPM2 rat MDAIKKKMQMLkLDKENAIDRAEQAEADkkQAEDRCKQLEEEQQALQkkLkGTEDEVEkYsEsVkDAQEkLEQAEkkAtDAEADVAsLNRRIQLVEEELDRAQERLAtALQkLEEAEkAADESERGMkVIENRAMkDEEkMELQEMQLkEAkHIAEDSDRkYEEVARkLVILEGELERsEERAEVAESKCGDLEEELkIVtNNLksLEAQADkYsTkEDkYEEEIkLLEEkLkEAEtRAEFAERSVAkLEktIDDLEDEVyAQkMKYkAIsEELDNALNDItsL
TPM2 iso2 rat MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLIAsEEEYsTkEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEkTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
  *****************************************************************:**************************************************************************************************************************::::*****::::::****:*::::********************************************::::::*:::::*:::**::*:::::*
Consensus MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARDLEEELRIMDNALKSLEAQADEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDELAAAKEENKAIHQELDNALNDINNL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.