Multiple Sequence Alignment:
Claudin-18	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 )
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Claudin-18 human	MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMG---GMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNyKAVs yHAsGHsVAyKPGGFKAStGFGSNTKNKKIyDGGARtEDEVQs yPsKHDyV
Claudin-18 iso2 human	MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVsIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMG---GMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDEVQSYPSKHDYV
Claudin-18 mouse	MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQDLYDNPVTAVFQYEGLWRSCVQQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVs yHAsGQNVAyRPGGFkAsTGFGsNTRNKKIyDGGARtEDDEQsHPtKyDyV
Claudin-18 rat	MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVQQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGIMFIISGVCAIIGVSVFANMLVTNFWMSTANMYSGMG---GMVQTVQTRYTFGAALFVGWIAGGLTLIGGVMMCIACRGLTPDDRNFKAVsYHAsGQNVAYkPGGFKASTGFGSNARNKkIYDGGARtEDDEQsHPTkYDYV
	:::*::::::::::*::*****::::****::****::******************::*************:*:***::::******************:* ******************:****************:::.:******:::**********::*********:::::***
Consensus	MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQDLYDNPVTAVFQYEGLWRSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGILVSIFALKCIRIGSMDDSAKANMTLTSGIMFIISGLCAIAGVSVFANMLVTNFWMSTANMYSGMG---GMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPDDTNFKAVSYHASGQNVAYKPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPSKHDYV

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.