Multiple Sequence Alignment:
SEPT5 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370         )
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SEPT5 human ----MSTGLr-----YKSKLAtPEDKQDIDKQyVGFAtLPNQVHRKSVKkGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLsAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDsDEDEDFKQQDRELKESAPFAVIGsNtVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSkLT-QDSRMEsPIPILPLPtPDAEtEkLIRMKDEELRRMQEMLQRMkQQMQDQ
SEPT5 iso2 human MDSLAAPQDRLVEQLLsPRTQAQrRLKDIDKQyVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEGALRLR-------EAAQHAHPHAYARPQGR----DVR-RALRELPRALHPADDQQTDPGQPHGEPHPDPAAAHPGRRD---------------------
SEPT5 mouse ----MSTGLR-----YKSKLAtPEDKQDIDKQyVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYkDRKLLSAEERINQTVEILKHTVDIEEkGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLrPVDVGFMKALHEkVNIVPLIAkADCLVPsEIRKLKDRIREEIDKFGIHVYQFPECDsDEDEDFKQQDRELkESAPFAVIGSNTVVEAkGQRVRGRLyPWGIVEVENQAHCDFVKLRNMLIRTHMHDLkDVTCDVHYENYRAHCIQQMTSkLt-QDsRMEsPIPILPLPtPDAEtEkLIRMKDEELRRMQEMLQKMKQQMQDQ
SEPT5 iso2 mouse MDSLAAPQDRLVEQLLsPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLT-QDSRMESPIPILPLPTPDAETEKLIRMKDEEGPVGR-------------
SEPT5 rat ----MSTGLR-----YKSKLAtPEDKQDIDKQyVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYkDRKLLSAEERINQTVEILKHTVDIEEkGVKLKLTIVDTPGFGDAVNNFECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFIsPFGHGLRPVDVGFMKALHEKVNIVPLIAkADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDsDEDEDFKQQDRELkESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLkDVTCDVHyENYRAHCIQQMTSkLt-QDSRMEsPIPILPLPTPDSETEkLIRMKDEELRRMQEMLQKMKQRMQDQ
SEPT5 iso2 rat MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQyVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNFECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAkADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLkDVTCDVHYENYRAHCIQQMTSkLT-QDSRMESPIPILPLPTPDSETEkLIRMKDEELRRMQEMLQKMKQRMQDQ
  ....:::::*.....::::::::::::****************************************************************:***********************************.************************************************************************************:*******************************************************************:::::::::::::::::::*:*::::::::::::::*::::::::::*: :*:::::*::::::*:**:::::::*::::::::::::::.:::.::::
Consensus MDSLAAPQDRLVEQLLKPRLAAQRRLQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNFECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLT-QDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQKMKQRMQDQ
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.