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TACC1 human	MAFsPWQILsPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEE-EDsQAEtKsLsFSsDsEGNFEtPEAEtPIRSPFk K75-m1 K75-ub ESCDPSLGLAGPGAKSQEsQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHsVKNFREEPEHDFSKIsIVRPFsIETKDSTDISAVLGtkAAHGCVTAVsGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNsCPELVPsRRsKLRKPkPVPLRkKAIGGEFsDTNAAVEGtPLPKASyHFsPEELDENtsPL-LGDARFQksPPDLKETPGTLSSDTNDsGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGsTLtPKIQKDGISksAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSY-HFDPDN--FDESMDPFKPTTTLTSSDFCSPTGNHVNEILEsPKKAKSRLI------------TSGCkVKkHETQSLALDACSRDEGAVISQISDISNRdGHAtDEEKLAST-SCGQkSAGAEVKGEPEEDLEyFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGEsPLDGICLSESDKTAVLTLIREEIItkEIEANEWKKKYEETRQEVLEMRk K640-ac K640-ub IVAEYEk K647-ac K647-ub TIAQMIEDEQRTSMTSQksFQQLTMEKEQALADLNSVERsLSDLFRRYENLKGVLEGFKKNEEALKkCAQDYLARVKQEEQRyQALkIHAEEKLDKANEEIAQVRTkAkAEsAALHAGLRKEQMKVESLERALQQkNQEIEELTkICDELIAkLGKTD
TACC1 iso2 human	MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEE-EDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPL-LGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSY-HFDPDN--FDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLITTTEQVKFLCFLLSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLAST-SCGQKSAGAEVKGEPEEDLEYFECSNVPVSTINHAFSSSEAGIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
TACC1 iso7 human	----------------------------------------------MNNILkLKSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPL-LGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHSVLQNSPPLSSEGSY-HFDPDN--FDESMDPFKPTTTLTSSDFCSPTGNHVNEILESPKKAKSRLI------------TSGCKVKKHETQSLALDACSRDEGAVISQISDISNRDGHATDEEKLAST-SCGQKSAGAEVK-----------------------------GIEKETCQKMEEDGSTVLGLLESSAEKAPVSVSCGGESPLDGICLSESDKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMTSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDKANEEIAQVRTKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
TACC1 mouse	MAFsPWQILsPVQWAKWTWSAVRGSGAGEDEAGGPEGDPEEEEDsQAETKSLSFSSDSEGNFETPEAETPIRSPLKEsCDSSPGLAEPEAKPQESREADEQLVAEVIEKCSPDTCSRSSENEAPQATVDSHPVKDVRGKAEHDVSKISVVRPFSIETRNCTDDPAALGTAAAHGCVPVLPGMALPSTTPEATQDEPVMDRGMGVTLEAFTEASLKTGGPCPEPVAS-RSKLRKPKPVSLRKKMA----PEPEMLMEGSPLPKASSPWLPDGLDQNANPSVLRGsGAQRsPLNLKETAGVLSNDTSDSGVEVAPGSPPLQL-E-DDFTEDGENVKIRSALPKQSGRKPSNKLAPSIRKDGVSKPVGVEQPSDPTVQDALLDQMsPKLDPSKRSHPPANFFGSGPILQNsPPLsSKCSH-HFDPNNINTDDSGDPCKPTPALTSSGFCPATGNHVNEILDSPKKAKSRLI------------TSGCKVKKYEAQPLDLDACsQDEGAVISKISEIPNRDGHAtDEEKLASTSSCAQKSAGAGVK-----------------------------GIEKETCQKMEKEELAVHGLLESSSEKAPVsVACGGEsPLDGICLSEADKTAVLTLIREEIITKEIEANEWKKKYEETREEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKkCAQDYLARVKQEEQRYQALKVHAEEKLDRANEEIAQVRSKAKAESAALHAGLRKEQMKVESLERALQQkNQEIEELTKICDELIAkLGKTD
TACC1 iso2 mouse	--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFSPWQILSPVQWAKWTWSAVRGSGAGEDEAGGP----------------EGDPEEEEDSQAETKSLSF------------RSGCKVKKYEAQPLDLDACSQDEGAVISKISEIPNRDGHATDEEKLASTSSCAQKSAGAGVK-----------------------------GIEKETCQKMEKEELAVHGLLESSSEKAPVSVACGGESPLDGICLSEADKTAVLTLIREEIITKEIEANEWKKKYEETREEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKVHAEEKLDRANEEIAQVRSKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD
TACC1 rat	MAFSPWQILSPVQWAKWTWSAVRGSGAGEDEAGGPEGDPEEEEDsQAEtKSLSFSSDSEGNFETPEAETPIRSSLKESCDSSLGLSEPEAKPQESREADEQPVAELIEKCSPDACSRSSGNEAPQATIDSYSVKDVRGKAEHDVSKISVVRPFSIETRDCTDDPA------AHGCVPVLPGKALPSTTPEATQDQPMMDRGMGVTLEAFTEVNLKTGGPCPEPVPS-RSRLRKPKPVSLRKKTAGDNTFEPEMLMEGSLLPKASSPWIPEESDKNSNPSLLRGLRAHKSPLNLKEAASIHCNSAGDSGVDLQEGSRASPLKL-DDFTEDGRSVETRSALPKQPGRKPSHKLAPNIRKDGSSKPVGVEQLTDPTIEDASLAQTSPKLDPSKWGRPNFNSFGSCPILQSSPPVSSKGSY-HLDPDNVNADESGDPCKPATALTGSGFCSATGNHVNEILDSPKKAQSRLI------------TSGCKVKKYETQSLDLDACSQDEGAVISQIADIPNRDGHATDEEKLAST-SCSQKSAGAEVK-----------------------------GVEKEAYQKMEEEELTVHGLLETSSEKAPVSVACGGESPLDGICLSEADKTAVLTLIREEIITKEIEANEWKKKYEETREEVLEMRKIVAEYEKTIAQMIEDEQRTNMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKVHAEEkLDRANEEIAQVRSKAKAESAALHAGLRREQMKVESLERALQQKNQEIEELTKICDELIAkLGKAD
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Consensus	MAFSPWQILSPVQWAKWTWSAVRGGAAGEDEAGGPEGDPEE-EDSQAETKSLSFSSDSEGNFETPEAETPIRSPFKESCDPSLGLAGPGAKSQESQEADEQLVAEVVEKCSSKTCSKPSENEVPQQAIDSHSVKNFREEPEHDFSKISIVRPFSIETKDSTDISAVLGTKAAHGCVTAVSGKALPSSPPDALQDEAMTEGSMGVTLEASAEADLKAGNSCPELVPSRRSKLRKPKPVPLRKKAIGGEFSDTNAAVEGTPLPKASYHFSPEELDENTSPL-LGDARFQKSPPDLKETPGTLSSDTNDSGVELGEESRSSPLKLEFDFTEDTGNIEARKALPRKLGRKLGSTLTPKIQKDGISKSAGLEQPTDPVARDGPLSQTSSKPDPSQWESPSFNPFGSHPVLQNSPPLSSEGSY-HFDPDN--FDESGDPFKPTTTLTSSDFCSPTGNHVNEILDSPKKAKSRLI------------TSGCKVKKHETQSLALDACSRDEGAVISQISDIPNRDGHATDEEKLAST-SCGQKSAGAEVK-----------------------------GIEKETCQKMEEDELTVHGLLESSAEKAPVSVACGGESPLDGICLSEADKTAVLTLIREEIITKEIEANEWKKKYEETRQEVLEMRKIVAEYEKTIAQMIEDEQRTSMSSQKSFQQLTMEKEQALADLNSVERSLSDLFRRYENLKGVLEGFKKNEEALKKCAQDYLARVKQEEQRYQALKIHAEEKLDRANEEIAQVRSKAKAESAALHAGLRKEQMKVESLERALQQKNQEIEELTKICDELIAKLGKTD