Multiple Sequence Alignment:
PRAS40 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |       
PRAS40 human --------------------MASGRPEELWEAVVGAAERFRARTGTELVLLtAAPPPPPrPGPCAYAAHGrGALAEAARRCLHDIALAHRAAtAARPPAPPPAPQPPsPtPsP-PRPtLAREDNEEDEDEPTETETSGEQLGISDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQYAKsLPVsVPVWGFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAEDTQVFGDLPRPRLNtsDFQkLKRKy
PRAS40 iso2 human -------------------------------------------------------------------------------------------------------------------------------------------------------MDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQYAKSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY
PRAS40 iso3 human MsFEGGDGAGPAMLATGTARMASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQPPSPTPSP-PRPTLAREDNEEDEDEPTETETSGEQLGISDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPTCSVPPASALPTQQYAKSLPVSVPVWGFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY
PRAS40 mouse --------------------MASGRPEELWEAVVGAAERFQARTGTELVLLTAAPPPPPRPGPCAYAAHGrGALAEAARRCLHDIAQAHRAATATRPPGPPPAPQPPsPAPsPPPRPALAREDEEEDEDEPTETETsGERLGGSDNGGLFMMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPTACPQPPATALPTQQYAKsLPVSVPVWAFKEKRtEARssDEENGPPssPDLDRIAAsMRALVLREAEDTQVFGDLPRPRLNtsDFQKLKRKy
PRAS40 rat --------------------MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIAQAHRAATATRPPGPPPAPQPPsPAPSSPPRPALAREEDEEDEDEPTETETsGERLGGSDNGGLFMMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPAYPKLPATALPTQQYAKsLPVSVPVWAFKEKRTEARssDEENGPPssPDLDRIAASMRALVLREAEDNQVFGDLPRPRLNtSDFQKLKRKY
PRAS40 cow --------------------MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAAAAARPPVPPPAPQPPSPARSP-PRPALAREEDEEDEDEPTETETSGERLGVSDNGGLFVMDEDTTLQDLPPFCESDPESTDDGSLSEETPAGPPAYSVPPASALPTQQYAKsLPVSVPVWAFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNtSDFQKLKRKY
                      ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::.::::::::::::::.::::::::..:::::::::::::::.::.:::::::.****:*****************************::::::**:******************:****************************************:***********************
Consensus --------------------MASGRPEELWEAVVGAAERFRARTGTELVLLTAAPPPPPRPGPCAYAAHGRGALAEAARRCLHDIALAHRAATAARPPAPPPAPQPPSPAPSP-PRPALAREDNEEDEDEPTETETSGERLGGSDNGGLFVMDEDATLQDLPPFCESDPESTDDGSLSEETPAGPPACSVPPASALPTQQYAKSLPVSVPVWAFKEKRTEARSSDEENGPPSSPDLDRIAASMRALVLREAEDTQVFGDLPRPRLNTSDFQKLKRKY
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.