Multiple Sequence Alignment:
SFRS14 Download MSA
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SFRS14 human MAARRItQEtFDAVLQEkAKRYHMDASGEAVSETLQFkAQDLLRAVPRsRAEMyDDVHsDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSsNPsISDDsYFRKECGRDLEFsHSDSRDQVIGHRkLGHFRsQDWkFALRGsWEQDFGHPVSQESSWSQEySFGPSAVLGDFGSSRLIEkECLEkESRDYDVDHPGEADsVLrGGSQVQArGrALNIVDQEGsLLGkGETQGLLTAkGGVGkLVTLRNVSTKKIPTVNRItPkTQGTNQIQkNtPsPDVtLGtNPGTEDIQFPIQkIPLGLDLkNLRLPRRkMsFDIIDkSDVFSRFGIEIIKWAGFHTIkDDIKFsQLFQTLFELETETCAKMLASFkCSLKPEHRDFCFFTIKFLkHSALkTPRVDNEFLNMLLDkGAVKTkNCFFEIIkPFDkyIMRLQDRLLKSVTPLLMACNAYELSVKMKtLSNPLDLALALETTNSLCRkSLALLGQTFSLASSFRQEKILEAVGLQDIAPsPAAFPNFEDSTLFGREYIDHLkAWLVSSGCPLQVkkAEPEPMREEEkMIPPtkPEIQAKAPssLsDAVPQRADHRVVGTIDQLVkRVIEGSLsPkERTLLkEDPAYWFLSDENSLEYKYYKLkLAEMQRMSENLRGADQkPTSADCAVRAMLYSRAVRNLKKkLLPWQRRGLLRAQGLrGWKARRATTGTQTLLSsGtRLKHHGRQAPGLSQAKPsLPDRNDAAKDCPPDPVGPsPQDPSLEAsGPsPKPAGVDISEAPQTSsPCPSADIDMKTMETAEkLARFVAQVGPEIEQFsIENstDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHtGGGDTTGsQESPVDLMEGEAEFEDEPPPREAELEsPEVMPEEEDEDDEDG-----GEEA----PA--PGGAGKSEGSTPADGLPGEAAEDDLAGAPALsQASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAyDRPRGRPMSKKKKPKDLDFAQQkLTDkNLGFQMLQkMGWkEGHGLGsLGkGIREPVSVGtPsEGE--GLGADGQEHKED--------------TFDVFRQRMMQMYRHKRANK
SFRS14 iso3 human MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNtPsPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMsFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPsPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPE---------------------------------------------------------------ASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVYAAGSLGWEWVGPQSFHLQPAAWLLHSQDGLQLAVDFCFLNRRHLQMRS------
SFRS14 mouse MAARRMAQESLDSVLQEKSKRYGD---SEAVGEALHLKAQDLLRTGSRARADVYEDIHGDSRYSASGSGVYSLDMGREGLRGDMFVGPSFRSSNQSVGEDSYLRKECGRDLEPAHTDSRDQSFGHRNLGHFPsQDWKLALRGSWEQDLGHSVSQESSWSQEYGFGPSL-LGDLASSR-----RMEKESRDYDLDHPGEVDSVSRSSGQVLTRGRsLNIADQEGTLLGKGDTQGLLGAK-GVGKLITLKSMTTKKIPVASRITSKPQGTNQIQKPTPSPDVTIGTSPVLDEIQFAALKIPLGLDLRTLGLPRRKMGFDAIDKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLkPEHRDFCFFTIkFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKSIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAMALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAYFPNFEDSTLFGREYIDHLKAWLMASGYPLQLKRAVPPESREQK-------TTAQTWASSTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLIRSQGPRGLKAKKATTAQQTSLSSGTRQKHHGRQASGSLRVKPPPRDSSDAAQDCLSEPAKPCPQPssPGALGPsPRPTGADDSEALPASSRCPSANMDAKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGE--------AGDSVQSPTAGKEGKGEPQEGHPEQEASLEGTEVLPEEEEEDEEEs-EDEGGEETSTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQASTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDMEFSQQKLTDKNVGFQMLQKMGWKEGHGLGSLGKGIREPVSVGALSEGE--GLGADGPEQKE--------------DTFDVFRQRMMQMYRHKRASK
SFRS14 rat MAARRMAQESLDTVLQDKSKRYGD---SEAVGEALHLKAQDLLRTGSRARADVYEDIHGDSRCSVSGSAVYSLDLGREGLRGDMFVGPSFRSSNQSVGEDSYLRKECGRDLEPAHTDSRDQSFGHRNLGHFPSQDWKLALRGSWEQDLGHSVSQESSWSQEYGFGPSL-LGDLASSR-----RMEKESRDFDLDHPGEVDSVSRSSGQVLARGRsLNMADQEGTLIGKGDTQGLLGAK-GVGkLITLKSMTTKKIPVVSRITSKPQGTNQIQKAAPsPDVTVGAsPVLDEIQFAALKIPLGMDLRTLSFPRRKLGFDAIDKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCKKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAYFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPPEPREQK-------TTAQTWAASTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRGLKPKKATTAQQISLSSGTRLKHHGRQASGSLRVKPPPRDSSDAAQDCLPEPAKPCAQPSSPGALGPSPQPAAGDDSEALPASSRCSSANMDAKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGE--------AGDSVQSPTAGKEGKGEPEEGRPEQEAALEGSEVLPEEEEEDEEEsEEDEGGEETCTLTPQTGAAKCPGSEGSSPTESIPGEGAREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDLEFSQQKLTDKNVGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTLSEGE--GLGADGPEQKE--------------DTFDVFRQRMMQMYRHKRASK
  *****::**::*:***:*:***::...:***:*:*::*******:::*:**::*:*:*:*:*:*:***:::*:*:******:*:*:********:*:::***:*********::*:*****::***:****:*****:*********:**:***********:****:.***::***.....::******:*:*****:***:*:::**::***:**::****:*:***:*****:**.*****:**::::*****:::***:*:********::******:*::*::::***:::*****:**::*.:****::**:***:**********************:**********************************************************************************:**********:********************::*****.*********:***********************************:**********************::**:***:*:*:*::.**::.......:::*::*:*:**:***********:******:***:*:***:*****::**********:*************:**:::::::::::**:*:********::***:**::*******:*:*:**:**:*:::***::*::******:*******:*::::**:::*::***:**:::*::*::*::*::*:****.*:::*:***:::**:*:**::*:****************************************:********:**:******:*:*:::........:::*::**::::**::*::::.*::**:**:.*:.::::.::.:.. ....::::....::.....:..::::.::...::::...:.:.::::::****:****************************:*****************::*******::*:********:*****************************:::::::  ::*:::.:.::.             .:*:::::*::**::::::.:
Consensus MAARRIAQESLDAVLQEKAKRYGDDASGEAVGEALQLKAQDLLRAGPRARADMYDDIHGDGRYSLSGSVAHSRDAGREGLRGDMFPGPSFRSSNQSIGDDSYLRKECGRDLEFAHSDSRDQSIGHRNLGHFRSQDWKLALRGSWEQDLGHPVSQESSWSQEYGFGPSAVLGDLASSRLIEKERLEKESRDYDLDHPGEADSVLRGGGQVQARGRALNIADQEGSLLGKGDTQGLLGAKGGVGKLITLRNMSTKKIPTVNRITPKPQGTNQIQKNTPSPDVTLGTNPGLDDIQFAAQKIPLGLDLRNLRLPRRKMGFDAIDKADVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLMASGCPLQVKRAEPEEMREQEKMIPPTKPEAQAKAPSSLSDAVPQRADHRVVDTIDQLVKRVIQGRLSPRERTLLLQDPAYWFLSDENSLEYKYYKLKLAEMQRLNENLRGADRRPTPADCAVRAMLYARAVRNLKRRLLPWQRRRLLRAQGLRGLKARRATTAQQTLLSSGTRLKHHGRQAPGLLRAKPPLRDRNDAAQDCLPDPAGPCPQDPSLEALGPSPKPAGVDDSEALQASSRCPSANIDAKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYREKVLELCPSICFQSSGENLHTGGGDAGDSQQSPTAGKEGEAEFEDEPPEREAELEGPEVLPEEEEEDEEES-EDEGGEET-TL-PQ-GAAKCPGSEGSSPTDSIPGEGAREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPIAKKKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGALSEGE--GLGADGPEQKE--------------DTFDVFRQRMMQMYRHKRASK
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.