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GRIN1 human	MDTAEDPAWLQLLQKDSSPPGPRPtAFFCPQDGSLGAGSSAMRDyCPSQQKAsPAPPRHtPDQsPGMESRHRsPsGAGEGASCSDGPRGSLACPsPtCFSPQEsPSKETLEAHGAsISGtPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFtGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKtyTVsPRKEDPGsLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLsGKRDPGPSGKADPMPLESMDSASTGKtEPGLLGKLIPGSSGKNGPVSsGtGAPGsLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVsGHTDTTASAK---------TDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLsPGQAERVsVGKAGtVsPGKEDPVSSRREDPISAGSRKTssEKVNPESSGKTNPVs-SGPGDPRSLGTAGPPsAVKAEPAtGGKGDPLSSEKAGLVASGKAAPTAsGKAEPLAVGKEDPVSKGKADAGPSGQGDSVsIGKVVsT-PGKTVPVPSGKVDPVSLGKAEAIPEGKVGsLPLEKGsPVtTTKADPRASGKAQPQsGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPS----RKTEsPsLGKVVPLsLEKTKPSSSSRQLDRKALGsARsPEGARGsEGRVEPKAEPVSSTEASSLG-QKDLEAAGAERsPCPEAAAPPPGPRTRDNFTKAPsWEASAPPPPREDAGTQAGAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPs----PPsRRDAGLQVsLGAAETRSVAtGPMtPQAAAP----PAFPEVRVRPGsALAAAVAPPEPAEPVRDVsWDEKGMTWEVYGAAMEVEVLGMAIQKHLERQIEEHGRQGAP--APPPAArAGPGrsGsVRtAPPDGAAKRPPGLFRALLQsVRRPRCCSRAGPTAE
GRIN1 iso2 human	MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRGSLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVSSVKTEPKSSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGRMDPMTVRKEDLGSLGKVDPLCSSKTYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDLVLSGKRDPGPSGKADPMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAK---------TDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVSVGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVS-SGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGKAEPLAVGKEDPVSKGKADAGPSGQGDSVSIGKVVST-PGKTVPVPSGKVDPVSLGKAEAIPEGKVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEAGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPS----RKTESPSLGKVVPLSLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRQASAR-PVPRAAAECAPAAVLLAGGTHGRVICPHFVRPSFRPSQAPFLITGP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
GRIN1 mouse	-----------------------------------------MRDCCSS-PKAIPAPPRHALDQSLGMDPRHTSSSGAAEGASCSERPAGSLACPsPNCsP-----LPEtPRAHGALTSDNSGTTLFGKPEPMSSAEATPTASEIRNPVFSGKMDGNSLKQADSTSTRKEEAGSLRNEESMLKGKAEPMIYGKGEPGTVGRVDCTASGAENSGsLGKVDMPCSSKVDIVsPGGDNAGsLRKVEtIssGKMDPKT---ENVMHsRRERPGst--------GEGDLVsL--------RENDMKPPDNTDSASTKKTDPEFSGKLtPGSSGKTELVSSVTVAPVTSENVNPVCSGGAGPAAVGNSETLSSVKKDPQLLGKKEAVSSGEGGSVSVRMAETVSARQPEGMFPAKtDSTSS--NSTGPSGRADPVSLRNSELVsPVKPERLsSGQAERVSLVKTETLSSGKEDPRSSRRVDHTTVTGNMQTsQKGNPESSGKTDLG-SSSSGDTRSLGTWGsLsAAKA-EVTEGKGDPQPWKKAsLPASE--------KTDPLASSKAGSASQGKAETVsPGEVDAMTLGKTVPTSSGKtALVsPGKVDLMTSERAEGIPEL----QAsEKGNPVNSTRVDTGATGSTEPKSGVKVITQIPG---AtsPGKVEtPsLQKEQPQLSEKTDPSRKVD--P--PttVEPVsLGKADsA--SPsPRKAESQTSAKTVPQAPDKA--TSsLRQsDGTPYSSAQPQRDTR--------SIGsLPEREPsAStsQKDLAAAAAQKsPsAEAAAPPPGPRTRDNFTKAPsWDAGAP-PPREDAGTQAGAQACVSVAVsPMsPQDGAGGPAFSFQAAPRAPsPAPRPPsRRDAGLQVsLGAAEtRsVAtGPMtPQAAAPPAVPPVFPEVRVRPGsVLAAALAPQEATEPVRDVsWDEKGMTWEVYGASMEVEVLGMAIQKHLERQIEEHGRQGAPAPAPPPAVRAGPGRAGSVRTAPAEGAAkRPPGLFRALLQsVRRPRCCSRAGPTAE
GRIN1 rat	MVSPKDPAWPHLLQRDSSPL----XSLCSPQDGSLGTGGPVMRDRCSS-PKAIPAPPRHILDQSLGMDSRHSSSSGAGEGASCAEKPVGSLA-----CSP-----LPETVRAHGALTSEASETTLFGKPEPMSSVEA-PSAAEVRNPSSSEKMDSNSLKQEDSTSSRKEGAGSLRKEESMLVGKTEPLICGKGASETGVRVECSAPKKEESGSLGTVDTACSSKVDIVPPGGENAGSLRKVETIASGKMDPRK---ENLMYSRREYPEST--------GEGDLVSP--------RGNDMKPPDK--------ADPGFSGELPPGSSGKTKHVSSVAVAPVTSENVNPASSGITDPVASGDTETLSSGKGDPRFLGKKEPVSTGESGPVSVRMAEPVSAGQPEGMVPAKKDPTSA--NSTGPSGRVDSVSLRNSELVSPVKPEHLSSGQAERVSLVKTETLFSGKEDPRSSGRVE-TTVTGNIKTFQKGNPESSGKTDPVSSFSSGDAGSLGTLGSLSAAKTETVTEGKGDPQSLEKASPTASE--------KADPLALCKESSASQGKAETVPSGEVGSTTLGKTASTSSGKTALVsPGKVDLTASERAEGVPEL----RAPEKGNPGNSTRVDT-----TEPKSGVKVVTQLPG---ATsPGKVEAPSLQKEQPQPSEKTDPSGKVD--P--TASVEPVSLGKADSASTSPSPRKAESQTSAKTVPQAPDKA--TSAFRQSDGTPYSSAQPRRDTR--------SIGALPEPEPSAsTsQKDLAAVAAQKsPSAEGAAPPPGPRTRDNFTKAPsWDAGAP-PPREDAGTQAGAQACVSVAVSPMSPQDGAVGPAFSFQAATRAPSPAPRPPSRRDAGLQVSLGAAETRSVATGPMtPQAAAPPAAPPVFPEVRVRPGSVLAAAMAPQEAAEPVRDVSWDEKGMTWEVYGASMEVEVLGMAIQKHLERQIEEHGRQGAP--APPPAVRAGPDRAGSVRTAPAEGAAKRPPGXFRALLQSVRRPRCCSRAGPTAE
	:....::::..:::.::::.....:....:::::::.:...***.*:*.:**:******::***:**::**.*:***:*****::.*:****::::.*::.....::**.:****::*.::::*::*****:**:::.*.:::.***.:::***.:*:**:****.:**.:**:*::::*:.**:**.*.***::.:.:*:::.:..:*.:****:**.:****:::*:*:::::******::::*:*:**.....*:.::*::*.*.*:........:::***:.........:.:*::*::..:::::.:::*:::*:*.******:..***:::**:::::::*:::*.::*:::*:.**:::.*.*:::***::::*:**:::**:::::::**..........:*.**:..:::::**::*:***:::::::::***.**:*******::*::*:::*****:**:*::.::::::..:::*:********::::.:::**::****:*::**:*::.:*:*****::.:**::.**:........*::***..*:.::*:***:::::*::::.::**:::*.:***::*::****:.::::**::**:.....:.***:*:::*::*:.:.:.::*:**:*:.*::**...*::**::::::*:**:**:***:**:.:::..*...:.:***********......**:**::::*:**::::*:..:*:.**:*:::::**::.:::*........::.:::..:::::.::::*:::::.:::::::::*:::*:::::::::*::.:.:: :::::::::::::::::::::::::::::.:.:::::::.::::....:::::::::::::::::::::::::::::::::....:::::::::::::::::.::.:..::::::::::::::::::::::::::::::::::::::::::::::::  ::::::::::.:.:::::::..:::::::::::::::::::::::::::::::
Consensus	MDTAEDPAWLQLLQKDSSPPGPRPTAFFCPQDGSLGAGSSAMRDYCPSQQKAIPAPPRHTLDQSLGMDSRHRSPSGAGEGASCSDGPRGSLACPSPTCFPPQESPLKETLRAHGALISGTPEATLFGKPEPMSSVEAEPKASDDRNPMFLEKMDFNSLKQADSTSIRKEDAGSLRKADPMLTGKAEPEILGKGDPVAPGRMDCMAVRKEDLGSLGKVDPLCSSKTDIVSPRGENAGSLRKVDPISSDKMDPVFPRKENPRYSRREHPVSSEKVAPTSAEEGDLVLSGKRDPGPSRKADMKPLDSMDSASTGKTDPGLLGKLIPGSSGKNGPVSSGTGAPGSLERLNPTCLGMADPAAVGNVETLPATKEDPRFLGKKDPASSGEGRPVSGRMAETASAKQPEGM-PAKTDLTSLKNNDPGPSGRVDPVSLRNMDLMCPGKPELLSPGQAERVSLGKAETLSPGKEDPRSSRREDPISAGGRKTSSQKGNPESSGKTNPVSSSGPGDPRSLGTAGPLSAAKAEPATEGKGDPQSSEKAGLVASEKAAPTASGKADPLAVGKEDPASQGKADAGPSGQGDSVSIGKTVSTSPGKTALVPPGKVDLVSLERAEAIPEGKVGSLALEKGNPVNSTRADPRASGKAQPQSGGKAETQLPGQEGAAAPGEAEAPCLQKEQPQASEKTDPGSCRDAEPLASGKGEPVSLGKADSAPSSPSPRKAESQSLAKTVPQALDKAKPSSSSRQLDRKALGSARPPRDARGSEGR---SIGPLPEAEASASTSQKDLAAAAAQRSPCAEAAAPPPGPRTRDNFTKAPSWDAGAP-PPREDAGTQAGAQACVSVAVSPMSPQDGAGGPAFSFQAAPRAPSPAPRPPSRRDAGLQVSLGAAETRSVATGPMTPQAAAPPA-PPVFPEVRVRPGSVLAAALAPQEAAEPVRDVSWDEKGMTWEVYGASMEVEVLGMAIQKHLERQIEEHGRQGAP--APPPAVRAGPGRAGSVRTAPAEGAAKRPPGLFRALLQSVRRPRCCSRAGPTAE