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DENND4B human	-----------MAEERPPRLVDyFVVAGLAGNGAPIPEETWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPVICYRRGRDkPPLVELGVLYEGKERPKPGFQVLDTTPySHSANLAPPGPGHPRTYLTYRRAAEGAGLHALGITDLCLVLPSkGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVErGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKkLLSPRTLPRRPYkVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLkSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGsELtVFItPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSrsAPSsPAPRRTKQEMKVAQRMAQkSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESkWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTtWAGRsLRDPAsPPGRLVkSGsLGSArGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEAGtPRRGLGARLQQLLtPsRHsPAsRIPPPELPPDLPPPARRsPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRsSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPKS--AGASGSkDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESGAWAYLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPS---HSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC
DENND4B mouse	MEADAVSEAEAMAEERPPRLVDYFVVAGLAGNGAPIPEEKWVPEPTGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQTSAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPaQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLMSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKPLSARTLPRRPYKLLLATLTSLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRTRLEREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGSRDVDNLFYLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPPVLEGSESTPQYCYDGFPELKAELFESPQEQqGAlpVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSATVPELWARCLLGHCYGLWFLCLPAYVRSVPSRVRALHTAYHVLREMENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLKDRRQQQQQQQQQQQQKQ--QVAEQQKSGsSQTEPYLERpSPTRpLQRQttWAGRSLREPsSPMGRLVKSGSLGSARGTQPTVEAGVAHMIEALGVLEPRGSPVPWQDGSLSDLSLTGEEMAPGGSPGGSGSALSAQSTEALEGISGRGsKTSGCQEEVGTPRkGlGARLQQLLTPSRRASASRIPPPElPSDLPPAARRSPMDSLLWPRERPGSTASESSASLGSEWDISESSLSSLSLRRSSERLSDTPGAFQPPSLEILMSSCSLCHACDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGCKDAPAPGGPGPVLSDRRFCLALDQPQLCNGHMGSASRRVENGAWAYLSPLVLRKELESLVENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSVLPGLVLASCNGPPPSQLSQGPSPWLTPDPASVHVHLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPSCLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRQRRAQMPTPKAIDCRKCFGAPLEC
	...........****************************:*****:**********************************:**********************************************:****************************:*******************************************************************************************************************************************************:*********************************************************************************************************:*************************************************************************************************:****:**:*********:******:********************************:**********************:************:*******:*************************************************:***********************************:::*****************:******:***:************************************:***************************:****:**********:**::**********************************:**************************************************::*:************:*..**:::*::****:*************************:*:**:**************:***************************:*************::**********************:****:*::*:*:*:****:**************:::**********:****:**********:*********************:******:***************:**:******:******:*******************************:***************:*****..*****:****:************:*****:*********:******:*********************************:********************:*********:**:...:**:************:*:*************************************::*************************************************************************************:********************:**
Consensus	MEADAVSEAEAMAEERPPRLVDYFVVAGLAGNGAPIPEEKWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKLGFQVLDTTPYSHSANLAPPGPGHPRTYLMYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQNLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQKEEKKLLSARTLPRRPYKLLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRNFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVDKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPALLEGSESTPQYCYDGFPELRAELFESLQEQQGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVRALHTAYHVLRQMENRKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRRAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRDRRQQQQQQQQQQQQQQQEQVAAQQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPMGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEPRGSPVPWQDGSLSDLSLTGEEMAPGGSPGGSGSALSAQSTEALEGISGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRRAPASRIPPPELPPDLPPAARRSPMDSLLHPRERPGSTASESSASLGSEWDISESSLSNLSLRRSSERLSDTPGAFQPPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACHFVPLLSVQTLDSRPSAPSPKSSLAGASGCKDAPAPGGPGPVLSDRRLCLALDQPQLCNGHMGGASRRVENGAWAYLSPLVLRKELESLVENEGSEVLALPELPAAHPIIFWNLLWYFQRLRLPSILPGLVLASCNGPPPSQHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPACLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRQRRAQMPTPKAIDCRKCFGAPLEC