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calpastatin human	-----------------------------------------------------------------------------------MNPtETKAIPVSQQMEGPHLPNKKKHKKQAVkTEPEKKSQsTkLsVVHEKksQEGkPkEHTEPKsLPKQAsDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIsAGGEsVAGITAIS---GkPGDKKKEKKsLtPAVPVEsKPDkPsGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVsDPMsstyIEELGKREVTIPPk K204-ac K204-ub YRELLAKkEGITGPPADSsKPIGPDDAIDALssDFtCGsPtAAGkKTEKEESTEVLk K261-m1 K261-ub AQSAGtVRSAAPPQEKKRKVEkDTMsDQALEALsAsLGtRQAEPELDLRsIkEVDEAKAKEEKLEKCGEDDETIPSEyRLKPATDKDGKPLLPEPEEKPkPRsEsELIDELsEDFDRsECKEKPSKPtEKTEESKAAAPAPVSEAVCRTsMCsIQsAPPEPATLKGTVPDDAVEALADsLGk K443-ac K443-ub KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDyRLEEVKDKDGkPLLPKEsk K500-ac K500-ub EQLPPMsEDFLLDALsEDFSGPQNAssLkFEDAkLAAAISEVVSQtPAsTTQAGAPPRDtsQsDKDLDDALDk K573-ac K573-ub LsDsLGQRQPDPDENKPMEDKVKEKAKAEHRDk K606-ac K606-ub LGERDDtIPPEyRHLLDDNGQDk K629-ac K629-ub PVkPPTkKSEDSKKPADDQDPIDALsGDLDsCPStTETsQNtAKDKCKkAASSSkAPkNGGkAKDSAKTTEETSKPKDD------
calpastatin iso2 human	---------------------------------------------------MN---------PTETKAIPVSQQM-E----------------------GPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS---GKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLA-------------KPIGPDDAIDALSSDFTCGsPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD------
calpastatin iso5 human	MsQPGQKPAAsPRPRRAAAARRTHEHVSEKTsEsPSKPGEKKGSDEKk K48-m1 K48-ub AAsLGssQssRtyAGGTAsATkVSAsSGA----------------------TSksSsMNPtEtKAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS---GKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLA-------------KPIGPDDAIDALSSDFTCGsPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD------
calpastatin iso6 human	MsQPGQKPAAsPRPRRAAAARRTHEHVSEKTsEsPSKPGEKKGSDEKkAAsLGsSQSSRTYAGGTAsATkVSAsSGATSksSsMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS---GKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD------
calpastatin iso7 human	-----------------------------------------------------------------------------------MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS---GKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVSRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD------
calpastatin mouse	MSQPGPKPAAsPRPsRGAAARHTQEHVNEKNIGSSSKPGEKKGSDEKkAAsLGssQPsRPHVGEAATATKVTASSAATSKsPsMstTETKAIPVNKQLEGPDQKR---PREQAVKTESK-KPQSsEQPVVHEKK-SKGGPKEGSEPKNLPKHTSSTGSKHAHKEKALsRsNEQMVSEKPSEsKTKFQDVPSAGGESVAGGGTVATALDKVVGKKKEQKPFtPAsPVQStPsKPsDKSGMDAALDDLIDTLGGHEDTNRDDPPYTGPVVLDPMYSTYLEALGIKEGTIPPEYRKLLEKNEGItQPLPDsPKPMGtDQAIDALsSDFtCssPtGKQSEKE-KSTGEIFkAQSAGVTRSSVPPKEKKRKVEEEVINDQALQALSDSLGTRQPDPPSHVSQAEQVKEAKAKEERQEKCGEDEDTVPAEYRLKPAKDKDGKPLLPEPEETSKsLsEsELIGELSADFDRSTYQDkPStPAEkksND--TSQtPPGETVPRASMCsIRSAPPKLAsLkGVVPEDAVEtLAGsLGTREADPEHEKTVEDKVKEKAKEEEHEKLGEKEETVPPDYRLEEVKDKDGKPLLPKESQEQLAPLSDDFLLDALSQDFSSPANIsSLEFEDAKLSAAISEVVSQtPAPSTHAAAPLPGTEQKDKELDDALDELsDsLGQRPPDPDENKPLDDKVKEkIKPEHSEkLGERDDTIPPEYRHLLDNDGKDKPEKPPTKKTE---KPDQDRDPIDALsEDLDSCPSTTETSKNTAKGKSKKT-SSSKASKDGEKTKDSSKKTEEVSKPKAKEDARHS
calpastatin iso3 mouse	MSQPGPKPAASPRPSRGAAARHTQEHVNEKNIGSSSKPGEKKGSDEKKAASLGSSQPSRPHVGEAATATKVTASSAATSKSPSMSTTETKA----------------------VKTESK-KPQSSEQPVVHEKK-SKGGPKEGSEPKNLPKHTSSTGSKHAHKEKALSRSNEQMVSEKPSESKTKFQDVPSAGGESVAGGGTVATALDKVVGKKKEQKPFTPASPVQSTPSKPSDKSGMDAALDDLIDTLGGHEDTNRDDPPYTGPVVLDPMYSTYLEALGIKEGTIPPEYRKLLEKNEGITQPLPDSPK------------------------------STGEIFKAQSAGVTRSSVPPKEKKRKVEEEVINDQALQALSDSLGTRQPDPPSHVSQAEQVKEAKAKEERQEKCGEDEDTVPAEYRLKPAKDKDGKPLLPEPEETSKSLSESELIGELSADFDRSTYQDKPSTPAEKKSND--TSQTPPGETVPRASMCSIRSAPPKLASLKGVVPEDAVETLAGSLGTREADPEHEKTVEDKVKEKAKEEEHEKLGEKEETVPPDYRLEEVKDKDGKPLLPKESQEQLAPLSDDFLLDALSQDFSSPANISSLEFEDAKLSAAISEVVSQTPAPSTHAAAPLPGTEQKDKELDDALDELSDSLGQRPPDPDENKPLDDKVKEKIKPEHSEKLGERDDTIPPEYRHLLDNDGKDKPEKPPTKKTE---KPDQDRDPIDALSEDLDSCPSTTETSKNTAKGKSKKT-SSSKASKDGEKTKDSSKKTEEVSKPKAKEDARHS
calpastatin rat	MSRPGPKPAASSRPRRGAAASHTQEHVNEKNIGSSSkPAEkKGSDEVTASS------------------------AATGTsPRMSTTGA----------------------KAVkIESE-KSQSSEPPVIHEKK-PKGKPKEGSEPQTLPKHASDTGSKHAHKEKALSRsNEQIVSEKSSESKTKFQDAPSADGESVAGGVTVATASDKVVVKKKEKKsLtPTLPMESTLNKLSDKSGVNAALDDLIDTLGECEDTNKDDPPYTGPVVLDPMDSTYLEALGIKEGTIPPEYRKLLEKNEAITGPLPDsPKPMGIDHAIDALsSDFTCSsPTGKQTEKE-KSTGESSKAQSAGVTRSAVPPQEKKRKVEEEVMNDQALQALSDSLGTRQPDPQSHLRQAKQVKEAKAKEERQEKCGEDEDTVPAEYRLKPAKDkDGkPLLPEPEETSKCLSESELIGELSADFVQPTYQEKPSMPAAK--------------------------------IKKGVVPDDAVETLARSLGTRKEDPEDEKSLVDkVKEKAKEEDHEkLGEKEETIPPDyRLEIVKDKDGkPLLPKEAEEQLPPLSDDFLLDALSQDFSSPANILSLGFEDAKLSAAVSETVSQVPAPSNHTAAPPPGTERRDkELDDALDELsDsLGQRQPDPDENkPLDDkVKEKIKAEHSEKLGERDDTIPPEYRHLLDNDGkDKPEkPLTKNTE---KLGQDQDPIDALsEDLDSCPPTTETSQNTTKEKGKkT-SSSKASkNEEkTKDSSKKTEEVPKPKVDEDAT--
	............................................................................:......:..:.:......................::**:*::.*:**::::*:****.::*:***::**::***::*:***::**::**:***:**::***::*:***:**::**:******:::::.. :*:::****:*::**::*::*:::*:*:***::***********::*:*::::::****:*:***:***:*:**::*:****:**:**::.::::.:.:::.*:::.:.::::::::::::::::::.:::.::::*::******::**::**:*******:::::****:***:******::*:::::::::*:*******::******::*:*:*******:*************::*::******:***:**:::::::***:*::*::::..::::::::::.:::::::::::::::::**:**:****:**:***::::***::*:::**********::*********:*******:*************::***:*:*:********:***:*:*::**:******:**:**:***:**::::::**:::*:::**:******:********:********::******:*:**::******************::*:***:**:**::*...*:::*:*******:******:*****:**:*:*:**:.*****:*:::*:***:*:***::***::...
Consensus	MSQPGPKPAASPRPRRGAAARHTQEHVNEKNIGSSSKPGEKKGSDEKKAASLGSSQ-SR---G--A-ATKVSASSAAT--S--MNPTETKAIPV--Q-EGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS---GKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKNEGITGPLADSPKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD------