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JMJD2B human	MGSEDHGAQNPSCKIMTFRPTMEEFkDFNkyVAyIEsQGAHRAGLAKIIPPkEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKkAMTVGEYRRLANSEkYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLysINyLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHkMTLISPIILkkYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGkVAtQCTCRKDMVKISMDVFVRILQPERYELWkQGkDLTVLDHtRPTALTsPELSSWSASRAsLKAKLLRR----------------------------------SHRKRSQPkKPkPEDPkFPGEGTAGAALLEEAGGSVk K409-ac K409-sm EEAGPEVDPEEEEEEPQPLPHGREAEGAEEDGRGKLRPTKAKSERKKKSFGLLPPQLPPPPAHFPSEEALWLPSPLEPPVLGPGPAAMEESPLPAPLNVVPPEVPSEELEAKPRPIIPMLYVVPRPGkAAFNQEHVSCQQAFEHFAQkGPTWkEPVsPMELTGPEDGAAsSGAGRMETKARAGEGQAPSTFSk K602-ac K602-ub LKMEIKKSRRHPLGRPPTRsPLsVVKQEAssDEEASPFSGEEDVSDPDALRPLLSLQWKNRAAsFQAERkFNAAAARTEPYCAICTLFYPYCQALQTEKEAPIAsLGKGCPATLPSKSRQkTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPLIACGKCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLkCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHkSGGHAVQLLRAVsLGQVVITkNRNGLYYRCRVIGAASQTCYEVNFDDGSYSDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQLTVKRGDIFTLEEELPkRVRSRLSLSTGAPQEPAFSGEEAkAAKRPRVGtPLA--TEDSGRSQDyVAFVESLLQVQGRPGAPF
JMJD2B mouse	MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVAtQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSIKAKLLRRQIsVKESRPWRKAEE------ERRREPtRRPGPAsHRRRSQPKKsKPEESRsPGEATAGVSTLDEARGCSRGEAMPE---DEEEEELLP-SQGHEAEGVEEDGRGKPRPTKARNKKKTPSP-SsPPLLsAPPALFPtEEVLRPPPQPKSPGPAMGPMAAEGGPPPTPLNVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQ---------------LAPMEL-GPEE----------ENQAQAGDSQGTTPFSKLKVEIKKSRRHPLGRPPtRsPLSVVKQEAssDEEAFLFSGEDDVTDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFYPYSQSVQTER--------DSA-VQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLsLSTGTPQEPSFSGDDVKAAKRPRVAsVLATTTEDTGRSPEYLSFMESLLQAQGRPGAPF
JMJD2B iso4 mouse	------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------XVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQ---------------LAPMEL-GPEE----------ENQAQAGDSQ-------LKVEIKKSRRHPLGRPPTRSPLSVVKQEAssDE------GEDDVTDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFYPYSQSVQTER--------DSA-VQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDDVKAAKRPRVASVLATTTEDTGRSPEYLSFMESLLQAQGRPGAPF
JMJD2B rat	MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRSILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEEERRPSLERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRRETMPE---EEEEEELSP-SQGHEAEGVEEDGRGKPRPTKARSKKKTPSL-LSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTALNVVPPGVPGEETEVRPRPIIPMLYVLPRANSSDGDREHAAHPQ---------------LAPMEL-GPEE----------EDQAQAGDSQGTTSFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDGSDPEALRSLLSLQWKSKAASFQAERKLNAAAALSEPYCAVCTLFYPYSQSVQTEREV-LATPGDSA-VQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCVYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRADIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDGVKAAKRPRVATVLATTTEDTGRSPEYLAFMESLLQAQGQPGAPF
	::::::.:::::::::::::::.::.:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::.:::::::::::::.:::::::::::::.:::::::...............      .............:::.::::::.:::....:::.::::..:.::.:....:..::   .:::::..: ..:.::::::::::::.:::::....:..:. ..::.:..:::.::.::::..:.....:....::::.:..:.::::*****::*.**:*::**********:**:.::::::**::::*               ::**** ***:          *.:*:**::*:...:::**:******************************::..::**:*::**:***:*******::*********:*****::*****:*******:*::***:.. .....::: :::****:*:************:************:*:*******:*::***********:****::****************************:**::*************:********:***:************:*******:*********************************************:::*:::****:*****:*****************:::**:************************::****:***************:*:***::**:****************:**********************:****:***:.:********:::**::***:***::*::*:*****:**:*****
Consensus	MGSEDHSAQNPSCKIMTFRPTMDEFRDFNRYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWNIGNLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPIILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTCRKDMVKISMDVFVRILQPERYEQWKQGRDLTVLDHTRPTALSSPELSSWSASRTSLKAKLLRRQISVKESRPWRKAEE------ERRREPTRRPGPASHRRRSQPKKSKPEDSRSPGEATAGVAGLDEARGCSRREAMPE---EEEEEELQP-SQGHEAEGVEEDGRGKPRPTKARSKKKTPSL-LSPPLLSAPPALFPAEEVLRLPPQPKSPGPAMGPMAAEGGPPPTPLNVVPPGAPVEEAEVRPRPIIPMLYVLPRTSSTDGDREHSAHAQ---------------LAPMEL-GPEE----------ENQAQAGDSQGTTPFSKLKVEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEAFPFSGEDDVSDPEALRSLLSLQWKNKAASFQAERKFNAAAALSEPYCAICTLFYPYSQSVQTERE---A--GDSA-VQPPSKSGQRTRPLIPEMCFTSSGENTEPLPANSYVGEDGTSPLISCAHCCLQVHASCYGVRPELAKEGWTCSRCAAHAWTAECCLCNLRGGALQRTTEHRWIHVICAIAVPEVRFLNVIERNPVDVSAIPEQRWKLKCIYCRKRMKRVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYVVSITCLKHRASGAGGQLLRTVSLGQIVITKNRNGLYYRCRVIGTTAQTFYEVNFDDGSYSDNLYPESITSRDCLRLGPPPEGELVELRWTDGNLYRARFISMATSLIYQVEFEDGSQLTVKRGDIFTLEEELPKRVRSRLSLSTGTPQEPSFSGDDVKAAKRPRVASVLATTTEDTGRSPEYLAFMESLLQAQGRPGAPF