Multiple Sequence Alignment:
GRB7 Download MSA
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GRB7 human -----------------------MELDLSPPHLSSSPEDLCPAPGtPPGtPRPPDtPLPEEVKRsQPLLIPttGRKLREEERRAtSLPsIPNPFPELCsPPsQsPILGGPSSARGLLPRDASRPHVVKVysEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKyELFKssPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGS----GRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVyVVTQGRkLYGMPTDFGFCVKPNkLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKyGVQLyKNYQQAQSRHLHPSCLGsPPLRsAsDNTLVAMDFsGHAGRVIENPREALsVALEEAQAWRKKTNHRLsLPMPAsGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
GRB7 iso2 human -----------------------MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGS----GRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAACSW-----SGRVSGTP--------RALS-----------------SLCATCRK-------------------------------------------------------
GRB7 iso3 human MGKWRPGQGHTTGSVKPLSCSDAMELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGS----GRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
GRB7 mouse -----------------------MELDLSPTHLSSsPEDVCPTPAtPPEtPPPPDNPPPGDVKRSQPLPIPS-SRKLREEEFQATSLPSIPNPFPELCSPPSQKPILGGssGARGLLPRDSSRLCVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDESWGLVESHPYLALERGLEDHEFVVEVQEAWPVGGDSRFIFRKNFAKYELFKSPPHTLFPEKMVSSCLDAQTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPtDFGFCVKPNKLRNGHKGLHIFCSEDEQSRTCWLAAFRLFKYGVQLYkNYQQAQSRHLRLsYLGsPPLRSVsDNTLVAMDFSGHAGRVIDNPREALSAAMEEAQAWRKKTNHRLsLPtTCsGSSLSAAIHRTQPWFHGRISREESQRLIGQQGLVDGVFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEDEGCLYFSMDEGQTRFTDLLQLVEFHQLNRGILPCLLRHCCARVAL
GRB7 rat -----------------------MELDLSPSHLSSSPEDVCPTPGTPPETPPPPDNPPPGDVKRSQPLPIPS-SRKLREEEFQATSLPSIPNPFPELCSPPSQKPILGGSSGARGLLPRDSSRLCVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDENWGLVECHPYLALERGLEDHESVVEVQEAWPVGGDSRFIFRKNFAKYELFKSPPHTLFPEKMVSSCLDTPTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADINESNVYVVTQGRKLYGIPTDFGFCVKPNKLRNGHKGLHIFCSEDEQSRTCWLSAFRLFKYGVQLYKNYQQAQSRHLRLSYLGsPPLRSVSDNTLVAMDFSGHAGRVIENPQEALSAATEEAQAWRKKTNHRLSLPTPCSGLSLSAAIHRTQPWFHGRISREESQRLIGQQGLVDGVFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEDEGCLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCARVAL
                         *******:********:**:*:***:**:***:*:*::*******:**:.:*******::********************:*****:*:********:**::***************************************:*****:**:***********:*****:**********:*************:**:************::******************************....************************************:****************:********************:**************:***********************::*:********:******************:**:****:*:*****************:::**:*****:::::.:::**:*::::::::::::::::.:::::::::::::::***::::::::::::::.::.::::::.:::::::::::::::::::::::::::::::::::
Consensus -----------------------MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGS----GRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEDEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCARVAL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.