Multiple Sequence Alignment:
ARHGAP12 Download MSA
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ARHGAP12 human MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSKAFyVPAQyVKEVTRKALMPPVKQVAGLPNNSTKIMQsLHLQRsTENVNKLPELSSFGKPSSSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHsPKVSSQNRtRsFGHFPGPEFLDVEKTSFSQEQsCDsAGEGsERIHQDsEsGDELSSsStEQIRAttPPNQGRPDsPVyANLQELKISQSALPPLPGsPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHtLytsDytNEKWLkHVDDQGRQyyySADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHsTIVLDTNDkESPTASKPCFPENESSPSsPKHQDTASSPKDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMAsKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDsPGIEKHDkEkEQKDPKKLRsFkVSsIDSsEQKKTKKNLKKFLTRRPtLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIyRVsGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEkNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIFGR
ARHGAP12 iso2 human MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPSSSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHsTIVLDTNDK------------------------------DQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIFGR
ARHGAP12 iso3 human MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPSSSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTRDAsISkGDFQNPGDQ-----------------------------------------------EWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKESPTASKPCFPENESSPSsPKHQDT-----DQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIFGR
ARHGAP12 iso4 human
ARHGAP12 mouse --MAERSGKITAGQAYIEVEYDYEYDAKDRKIVIRQGERYLLVKKTNDDWWQVRPDENSKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRstENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHsPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQsCDsAGEGsERIQQDsEsGDELSSSSTEQMRAttPPNQGRPDsPVyANLQELKISQSALPPLPGsPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTS-RDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLyTSDyTKEKWLKHVDDQGRQYyYSADGSRSEWELPKYNASSQQQREIIKsRsLDRRLQEPIVLTKWRHstIVLDSNDKDSPTTTKLCLPENEsPPTSSKHQDP-----GQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFtVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEEtPDsPGVEKHDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPtLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQkLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR
ARHGAP12 iso3 mouse --MAERSGKITAGQAYIEVEYDYEYDAKDRKIVIRQGERYLLVKKTNDDWWQVRPDENSKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERIQQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTS-RDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHsTIVLDSND-------------------------K-----GQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEETPDSPGVEKHDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR
ARHGAP12 rat --MAERSGKIASGQVYIEVEYDYEYEAKDRKIVIRQGERYLLVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQTTGLPNNSMKTTQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDsAGEGSERTHQDsEsGDELSSSSTEQMRAttPPNQGRPDsPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTS-RDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDSND-------------------------K-----GQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGAAIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEEAPDsPGVEKQDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR
  ..**:*****::**:**********:********:*****:************::****************************::******:*::**:***********:***************************::**:***:**************:**************:***********:********************::****************:***************************************:*******************:***********:**:*:*.:***:**:*:.:::::::.:...:::::::::::::::::::::::::::::::.::*****************************************************************:**:.........................     :************:***************************************************:********************************:****************::*:**::***:*****:**:****:**::*****:*:**:********************************************************************:***************************************************************************:************************:****************************:************************::***
Consensus MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIRQGERYILVKKTNDDWWQVRPDENSKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSMKIMQSLHLQRSTENVNKLPELSSFGKPSSSVQGTGLIRDANQNFGPNYNQGQTLNLSLDLTHNNGKFNNDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWARDASISKRDFQNPGDQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDSNDK-SPT--K-C-PENES-P-S-KHQDK-----DQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQAAEADEAAEEEIPDSPGIEKHDKEKDQKDLKKLRSMKGSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSSIFGR
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.