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TPM1 human	MDAIKKKMQMLk K12-ac K12-ub LDk K15-ac K15-ub ENALDRAEQAEADk K29-ac K29-ub kAAEDRSkQLEDELVsLQk K48-ac K48-ub KLKGtEDELDkysEALKDAQEKLELAEKkAtDAEADVAsLNRRIQLVEEELDRAQERLAtALQk K112-ac K112-ub LEEAEk K118-ac K118-ub AADEsERGMKVIEsRAQKDEEKMEIQEIQLkEAKHIAEDADrk K161-ac K161-m1 yEEVARk K168-ac K168-ub LVIIEsDLERAEERAELSEGKCAELEEELKtVtNNLKsLEAQAEkysQKEDRyEEEIkVLsDkLkEAEtRAEFAERSVtk K248-ac K248-ub LEKsIDDLEDELyAQkLKykAIsEELDHALNDMtsI
TPM1 iso2 human	--------------------------------------------------------MCRLRIFLRTASSEHLHERKLRETAEADVAsLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDSDLEsINAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEk K195-ac K195-ub sIDDLEEkVAHAKEENLsMHQMLDQtLLELNNM
TPM1 iso3 human	MDAIKKKMQMLKLDKENALDRAEQAEADkKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKyEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDk K213-ac K213-ub YsQKEDRYEEEIKVLsDKLKEAETRAEFAERSVTKLEk K251-ac K251-ub sIDDLEEkVAHAKEENLsMHQMLDQtLLELNNM
TPM1 iso4 human
TPM1 iso5 human	-----------------------------MA-------GSSsLEAVRRKIRsLQEQADAAEERAGTLQRELDHERKLRETAEADVAsLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDQLYQQLEQNRRLTNELKLALNED---
TPM1 iso6 human	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDsLLAAEEAAAKAEADVAsLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
TPM1 iso7 human
TPM1 iso10 human	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDk K213-ac K213-ub YsQKEDRYEEEIKVLsDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTsM
TPM1 mouse	MDAIKKkMQMLkLDk K15-ac K15-ub ENALDRAEQAEADkkAAEDRSkQLEDELVsLQk K48-ac K48-ub k K49-ac K49-ub LkGTEDELDk K59-ac K59-ub ysEALkDAQEkLELAEkk K77-ac K77-ub ATDAEADVAsLNRRIQLVEEELDRAQERLATALQk K112-ac K112-ub LEEAEk K118-ac K118-ub AADESERGMkVIESRAQk K136-ac K136-ub DEEk K140-ac K140-ub MEIQEIQLk K149-ac K149-ub EAk K152-ac K152-ub HIAEDADRk K161-ac K161-ub yEEVARkLVIIEsDLERAEERAELsEGkCAELEEELktVTNNLk K205-ac K205-ub sLEAQAEk K213-ac K213-ub YsQk K217-ac K217-ub EDk K220-ac K220-ub yEEEIkVLSDkLk K233-ac K233-ub EAETRAEFAERSVTk K248-ac K248-ub LEk K251-ac K251-ub sIDDLEDELyAQk K264-ac K264-ub Lk K266-ac K266-ub YkAIsEELDHALNDMtsI
TPM1 iso2 mouse	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKsIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
TPM1 iso3 mouse	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSkQLEEDIAAKEKLLRASEDERDRVLEELHKAEDsLLAADETAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKsIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
TPM1 iso4 mouse	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDkYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKsIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
TPM1 iso10 mouse	-----------------------------MA-------GSSsLEAVRRKIRsLQEQADAAEERAGSLQRELDQERkLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKsIDDLEDQLYHQLEQNRRLTNELKLALNED---
TPM1 rat	MDAIKKKMQMLkLDKENALDRAEQAEADKKAAEDRSKQLEDELVsLQKKLKGTEDELDKysEALKDAQEKLELAEKkAtDAEADVAsLNRRIQLVEEELDRAQERLAtALQkLEEAEkAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRkyEEVARKLVIIEsDLERAEERAELSEGKCAELEEELKtVtNNLKsLEAQAEkYsQkEDkYEEEIKVLSDKLkEAEtRAEFAERSVTKLEKsIDDLEDELyAQkLKyKAISEELDHALNDMTsI
TPM1 rabbit	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTsI
TPM1 pig	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKYSEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTsI
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Consensus	MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKEKNKAISEELDHALNDMTSI