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TMPO human	MpEFLEDPsVLtk K13-ub K13-sm K13-sc DKLk K17-ub K17-sm sELVANNVtLPAGEQRKDVYVQLYLQHLTARNrPPLPAGtNsk K60-ac K60-ub GPPDFssDEEREPtPVLGsGAAAAGrsRAAVGRKAtKKtDKPRQEDkDDLDVt--ELtNEDLLDQLVkyGVNPG-PIVGtTRKLYEKKLLKLREQGtEsRsstPLPtIsssAENtRQNGsNDsDRysDNEEDsKIELKLEkREPLKGRAk K207-ac K207-m1 K207-ub tPVtLkQRRVEHNQsysQAGITETEWTsGSSkGGPLQALtREst-----R-------------GsRRtPRKRVEt--------------SEHFRI------DGPVIsESt----PIA--EtIMAssNEsLVVNRVtGNFk K303-m1 K303-ub HAsPILPItEFsDIPRRAPkkPLTRAEVGEk K334-ac K334-ub tE-ERRVERDILkEMFPyEAstPt---GIsAsC-RRPIkGAAG---------RPL---------ELsDFRMEEsFsskyVPk K393-ac K393-ub yVPLADVk K401-ub K401-sm sEkTKKGR------------------------------------------------SIPVWIKILLFVVVAVFLFLVYQAMETNQV-----------------------NPFSNFLHVDPRKSN----------------------------------------------------------------------------------------------------------------------------------------------
TMPO iso2 human	MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSKGPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVT--ELTNEDLLDQLVKYGVNPG-PIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDSDRYSDNEEDSKIELKLEKREPLKGRAKtPVTLKQRRVEHNQ---------------------------------------------------------------------------------------------------------------------------------------------------------VGEktE-ERRVERDILKEMFPYEASTPT---GISASC-RRPIKGAAG---------RPL---------ELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGR------------------------------------------------SIPVWIKILLFVVVAVFLFLVYQAMETNQV-----------------------NPFSNFLHVDPRKSN----------------------------------------------------------------------------------------------------------------------------------------------
TMPO iso6 human	MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSKGPPDFssDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVT--ELTNEDLLDQLVKYGVNPG-PIVGTTRKLYEKKLLKLREQGTEsRSstPLPTISSSAENTRQNGSNDsDrysDNEEGKKKEHKKVKST----RDIVP-------------FS-------ELGttPSGGGFFQGISFPEISTRPPLGSTELQAAKKVHTskGDLPREPLVAtNLPGrGQLQk K269-ub K269-sm LAsERNLFIsCk K281-m1 K281-ub K281-sm SSHDRCLEkSSSSSsQPEHSAMLVstAAsPsLIkETtTGYYkDIVENICGREksG------IQPLCPERSHIsDQsPLssk K356-ac K356-ub K356-sm RkALEESEssQLIsPPLAQAIRDYVNSLLVQGGVGSLPGTSNSMPPLDVENIQkRIDQSkFQETEFLs---PPRkVPRLsEk K435-ac K435-ub sVEERdsGsFVAFQNIPGSELMSsFAKTVVSHSLTtLGLEVAkQ-SQHDkIDASELSFPFHEsILkV-IEEE-----WQQVDrQLPSLACkYPVSSREATQILSVPKVDDEILGFISEATPLGGIQAASTESCNQQLDLALCRAYEAAASALQIATHTAFVAKAMQADISQAAQILSSDPSRTHQALGILSkTYDAASYICEAAFDEVKMAAHtMGNAtVGRRYLWLk K656-ac K656-ub DCkINLASkNk K667-ub K667-sm LAstPFk K674-m1 K674-ub K674-sm GGtLFGGEVCkVIKKRGNKH
TMPO mouse	MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANsKGPPDFssDEErEPtPVLGsGAs-VGr R85-m1 R85-m2 Gr R87-m1 R87-m2 GAVGrKATKKTDKPRLEDkDDLDVT--ELSNEELLDQLVRYGVNPG-PIVGTTRKLYEKKLLKLREQGtEsRsstPLPtVsssAENtRQNGsNDsDRysDNDEDsKIELKLEKREPLKGRAKtPVtLkQRRTEHNQSYSQAGVtETEWTSGSSTGGPLQALTREST-----R-------------GSRRTPRKRVEt--------------SQHFRI------DGAVIsEst----PIA--ETIkASsnEsLVANRLtGNFkHAssILPITEFsDItRRtPKKPLTRAEVGEktE-ERRVDRDILkEMFPYEAstPt---GISAsC-RRPIKGAAG---------RPL---------ELsDFRMEEsFsSkYVPkYAPLADVkSEkTKKRR------------------------------------------------SVPMWIKMLLFALVAVFLFLVYQAMETNQG-----------------------NPFTNFLQDTKISN-----------------------------------------------------------------------------------------------------------------------------------------------
TMPO iso2 mouse	MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFSSDEEREPTPVLGSGAS-VGRGRGAVGRKATKKTDKPRLEDKDDLDVT--ELSNEELLDQLVRYGVNPG-PIVGTTRKLYEKKLLKLREQGTESRSSTPLPTVSSSAENTRQNGSNDSDRYSDNDEDSKIELKLEKREPLKGRAKTPVTLKQRRTEHNQ--------------------------------------------------------------------------------------------------------------------VANRLTGNFKHASSILPITEFSDITRRTPKKPLTRAEVGEKTE-ERRVDRDILKEMFPYEASTPT---GISASC-RRPIKGAAG---------RPL---------ELSDFRMEESFSSKYVPKYAPLADVKSEKTKKRR------------------------------------------------SVPMWIKMLLFALVAVFLFLVYQAMETNQG-----------------------NPFTNFLQDTKISN-----------------------------------------------------------------------------------------------------------------------------------------------
TMPO iso6 mouse	MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFSSDEErEPTPVLGSGAS-VGrGrGAVGrKATKKTDKPRLEDKDDLDVT--ELSNEELLDQLVRYGVNPG-PIVGTTRKLYEKKLLKLREQGTESRSSTPLPTVSSSAENTRQNGSNDSDRYsDNDEGKKKEHKKVKSA----RDCVP-------------FS-------ELASTPS-GAFFQGIsFPEIsTRPPLGRTELQAAKKVQTTKRDPPRETCTDTALPGKGQTHKLAPGRSLFIPSESSYDRCVEKSSsPsSQREFAARLVsAAAsPsLIRETTTTYSKDIVENICrGGKSR------AQPLRAEEPGVSDQSVFSSEREVLQESERSQVIsPPLAQAIRDYVNSLLVQGGVGSLPGTSDSVPTLDVENICKRLsQssyQDSEsLs---PPRKVPRLSEKPARGGDSGSCVAFQNTPGSEHRSSFAKSVVSHSLTTLGVEVSKPPPQHDKIEASEPSFPLHESILKV-VEEE-----WQQIDRQLPSVACRYPVSSIEAARILSVPKVDDEILGFISEATPRAATQASSTESCDKHLDLALCRSYEAAASALQIAAHTAFVAKSLQADISQAAQIINSDPSDAQQALRILNRTYDAASYLCDAAFDEVRMSACAMGSSTMGRRYLWLKDCKIsPASKNKLTVAPFKGGTLFGGEVHKVIKKRGNKQ
TMPO rat	MPEFLEDPSVLTkDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFssDEEREPtPVLGSGAS-VGrGrGAVGrKATKKTDKPRPEDKDDLDVT--ELSNEELLEQLVRYGVNPG-PIVGTTRKLYEKKLLKLREQGAEsRsstPLPTVSSsAENTRQNGSNDsDRysDNDEDSKIELKLEKREPLKGRAktPVTLKQRRIEHNQSYSEAGVTETEWTSGSSKGGPLQALTREST-----R-------------GSRRTPRRRVEP--------------SQHFRV------DGAVISEST----PIA--ETIKASSNDSLVANRLTGNFKHASSILPITEFSDITRRTPKKPLTRAEVGEkTE-ERRVERDILKEMFPYEASTPT---GISASC-RRPIKGAAG---------RPL---------ELSDFRMEEsFSSkYVPkYVPLADVkSEKTKKGR------------------------------------------------SVPMWIKMLLFALVAGFLFLVYQAMETNQG-----------------------NPFTNFLQDTKISN-----------------------------------------------------------------------------------------------------------------------------------------------
TMPO cow	MPEFLEDPSVLTKEKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLATSANSKGPPDFSSDEEREPTPVLGSGAAVAGRSRAAVGRKATKKTDKPRPEDKDDLVIPLIEIKERHTLAQILRYSVIGGSSVAGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSVENTRQNGSNDSDRYSDNEEDSKIELKLEKREPLKGRAKtPVTLKQRRVEHNQSYSQAGVTETEWTSGSSKGGLLQALTREST-----R-------------GSRRTPRKRVET--------------SEHFRI------DGAIISEST----PIA--ETIMASSNETLVVNRVTGNFKHAAPILPITEFSDIPRRTPKKPLTRAEVGEKTE-ERRVERDILKEMFPFEAATPT---GISASC-RRPIKGAAG---------RPL---------ELSDFRMEESYSSKYIPKYVPLADVKSEKTKKGR------------------------------------------------SIPMWIKILLFVVVAGFLFLVYQAMETNQG-----------------------NPFYKFLSNDSKKVN----------------------------------------------------------------------------------------------------------------------------------------------
	*************:***************************************::::************************:.:**:*:**************.******:::  *::::::*:*:::*:*::* :::******************:**********:***:*****************:*::*:*:*::*::::::*:::*:::::::.::::..:.......:.....:.::..:.......     .             .....::.....              ......      :......:.    ...  ....:::...::.::.:::.::::.:::..:::.......::::.::::::::: :::::*::*:*::::::::*:   :*:::: :::::*::*         ::*         ::*:::::*::*::::*:::*::::*::::::.:                                                *.*.::::*::::::.::::::*::::::.                       :::.:*:..:.....
Consensus	MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFSSDEEREPTPVLGSGAA-AGRGRAAVGRKATKKTDKPRQEDKDDLDVT--ELSNEELLDQLVRYGVNPG-PIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDSDRYSDNDEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYS-AG-TETEWTSGSSKGGPLQALTREST-----R-------------GSRRTPRKRVET--------------SRHFRI------DGAVISEST----PIA--ETIKASSNESLVANRLTGNFKHASSILPITEFSDITRRTPKKPLTRAEVGEKTE-ERRVERDILKEMFPYEASTPT---GISASC-RRPIKGAAG---------RPL---------ELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGR------------------------------------------------SIPMWIKILLFAVVAVFLFLVYQAMETNQG-----------------------NPFTNFLQDDKIKNN----------------------------------------------------------------------------------------------------------------------------------------------