Multiple Sequence Alignment:
IGFBP3 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290         )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         
IGFBP3 human MQRARPtLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPA--VCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPA------PGNAsEsEEDRsAGsVEsPsVsstHRVsDPKFHPLHsKIIIIKKGHAKDsQRYKVDyEsQstDtQNFsSESKRETEyGPCRREMEDTLNHLKFLNVLsPRGVHIPNCDKKGFyKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTtKGKEDVHCYSMQSK
IGFBP3 iso2 human MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPA--VCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
IGFBP3 mouse MHPARPALWAAALTALTLLRGPPVARAGAGAVGAGPVVRCEPCDARALSQCAPPPTAPACTELVREPGCGCCLTCALREGDACGVYTERCGTGLRCQPRPAEQYPLRALLNGRGFCANASAAGSLSTYLPS-------QPAPGNISESEEEHNAGSVESQVVPSTHRVTDSkFHPLHAKMDVIKKGHARDSQRYKVDYESQSTDTQnFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYDTKGKDDVHCLSVQsQ
IGFBP3 rat MHPARPALWAAALTALTLLRGPPVARAGAGAVGAGPVVRCEPCDARALAQCAPPPTAPACTELVREPGCGCCLTCALREGDACGVYTERCGTGLRCQPRPAEQYPLKALLNGRGFCANASAASNLSAYLPS-------QPSPGNTTESEEDHNAGSVESQVVPSTHRVTDSKFHPLHSKMEVIIKGQARDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYDTKGKDDVHCLSVQSQ
  *::***:*******:*:************:::*:**************:******:..:*:****************:**::**:******:******:*:*::**.***:***:*:****::.*::**::....   .:.***::****:::******::*:*****:*:******:*:.:*:**:*:**********************************************************************************************:****:****:*:**:
Consensus MQRARPALWAAALTALTLLRGPPVARAGAGAAGAGPVVRCEPCDARALAQCAPPPAAPACAELVREPGCGCCLTCALREGDACGIYTERCGSGLRCQPRPAEARPLQALLNGRGLCANASAASRLRAYLLPAPPA---QPAPGNASESEEDRNAGSVESQSVPSTHRVSDPKFHPLHSKIIIIKKGHARDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYDTKGKDDVHCLSMQSQ
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.