Multiple Sequence Alignment:
TFPI Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320      )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |      
TFPI human MIYTMKKVHALWASVCLLLNLAPAPLNADsEEDEEHTIITDTELPPLKLMHsFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKttLQQEkPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNG------FQVDNYGT------QLNAVNNSLTPQSTKVPSLFEFHGP---SWCLtPAD-----RGLCRANENRFYY--NSVIGKCRPFKYSGCGGNENNFTSkQECLRACkk
GFIQRISKGGLIKTKRKRKKQRVkIAYEEIFVKNM
TFPI iso2 human MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNG------FQVDNYGT------QLNAVNNSLTPQSTKVPSLFVTKEGTNDGWKNAAHIYQVFLNAFCIHA-SMFFLGLDSISCLC--------------------------------------------------------------
TFPI mouse MTYKMKKEYAFWATVCLLLSLVPEFLNALSEEADD----TDSELGSMKPLHTFCAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCIPGYEKTAVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNnQTKQCERFVYGGCLGNRNNFETLDECKKICENPVHSPSPVNEVQMSDYVTDGNTVTDRSTVNNIVVPQsPKVPRRRDYRG---RPWCLQPAD-----SGLCKASERRFYY--NSATGKCHRFNYTGCGGNNNNFTTRRRCLRSCKTGLIKNKSKGVVKIQR--RKAPFVKVVYESIN----
TFPI rat
  *:*:***::*:**:*****:*:*::***:***:::::::**:**:::*::*:***:*********:::::***::*:*************:***::******:*:::::::::*:::::*:***********:****::**:***********:*******:******:***:***:::::......:*:::*:*......::::***:::***:***:::...:.....*::::::......::*.:::.:*::..:*:.::*..:.:.:::::.::::....:::.::.:.:...:::........::...::..::.:.....
Consensus MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNG------FQVDNYGT------QLNAVNNSLTPQSTKVPSLFDFRGG--RGWCLAPAD-----RGLCRAAERRFYY--NSAIGKCRRFNYSGCGGNNNNFTSRRRCLRACKKGLIQRISKGGLIIQR--RKAQRVKIAYEEIN----
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.