Multiple Sequence Alignment:
TFPI Download MSA
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TFPI human MIYTMKKVHALWASVCLLLNLAPAPLNADsEEDEEHTIITDTELPPLKLMHsFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKttLQQEkPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNG------FQVDNYGT------QLNAVNNSLTPQSTKVPSLFEFHGP---SWCLtPAD-----RGLCRANENRFYY--NSVIGKCRPFKYSGCGGNENNFTSkQECLRACkkGFIQRISKGGLIKTKRKRKKQRVkIAYEEIFVKNM
TFPI iso2 human MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNG------FQVDNYGT------QLNAVNNSLTPQSTKVPSLFVTKEGTNDGWKNAAHIYQVFLNAFCIHA-SMFFLGLDSISCLC--------------------------------------------------------------
TFPI mouse MTYKMKKEYAFWATVCLLLSLVPEFLNALSEEADD----TDSELGSMKPLHTFCAMKADDGPCKAMIRSYFFNMYTHQCEEFIYGGCEGNENRFDTLEECKKTCIPGYEKTAVKAASGAERPDFCFLEEDPGLCRGYMKRYLYNnQTKQCERFVYGGCLGNRNNFETLDECKKICENPVHSPSPVNEVQMSDYVTDGNTVTDRSTVNNIVVPQsPKVPRRRDYRG---RPWCLQPAD-----SGLCKASERRFYY--NSATGKCHRFNYTGCGGNNNNFTTRRRCLRSCKTGLIKNKSKGVVKIQR--RKAPFVKVVYESIN----
TFPI rat
  *:*:***::*:**:*****:*:*::***:***:::::::**:**:::*::*:***:*********:::::***::*:*************:***::******:*:::::::::*:::::*:***********:****::**:***********:*******:******:***:***:::::......:*:::*:*......::::***:::***:***:::...:.....*::::::......::*.:::.:*::..:*:.::*..:.:.:::::.::::....:::.::.:.:...:::........::...::..::.:.....
Consensus MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPNG------FQVDNYGT------QLNAVNNSLTPQSTKVPSLFDFRGG--RGWCLAPAD-----RGLCRAAERRFYY--NSAIGKCRRFNYSGCGGNNNNFTSRRRCLRACKKGLIQRISKGGLIIQR--RKAQRVKIAYEEIN----
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.