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PTP-PEST human	MEQVEILRKFIQRVQAMKsPDHNGEDNFARDFMRLRRLstKYRTEKIYPTATGEKEENVKKNRyKDILPFDHSRVKLTLKTPsQDSDyINANFIkGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTkEQYELVHRAIAQLFEKQLQLyEIHGAQKIADGVNEINtENMVssIEPEKQDsPPPKPPRTRsCLVEGDAKEEILQPPEPHPVPPILTPsPPSAFPTVTTVWQDNDRYHPKPVLHMVssEQHsADLNRNYSKsTELPGKNESTIEQIDKKLERNLsFEIKKVPLQEGPKsFDGNtLLNRGHAIKIKs--AsPCIADKISKPQELS-SDLNVGDtsQNsCVDCSVTQSNKVsVtPPEE-SQNsDtPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKtVsLtPsPtTQVEtPDLVDHDNTsPLFRtPLsFTNPLHsDDsDsDERNsDGAVTQNKtNISTASATVSAATsTESISTRKVLPMsIARHNIAGTTHsGAEKDVDVsEDsPPPLPERtPESFVLAsEHNtPVRSEWSELQSQERsEQKKsEGLITsENEKCDHPAGGIHyEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWt
PTP-PEST iso2 human	----------------------------------------------------------------------------------------------------------------------------------MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKS--ASPCIADKISKPQELS-SDLNVGDTSQNSCVDCSVTQSNKVSVTPPEE-SQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
PTP-PEST iso3 human	-----------------------------------------------------------------------------------------------------------------------MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKS--ASPCIADKISKPQELS-SDLNVGDTSQNSCVDCSVTQSNKVSVTPPEE-SQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
PTP-PEST mouse	MEQVEILRRFIQRVQAMKsPDHNGEDNFARDFMRLRRLsTKYRTEKIYPTATGEKEENVKKNRyKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCENEQARTDYFIRTLLLEFQNEsRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEkQLQLYEIHGAQKIADG-NEITTGtMVssIDsEKQDsPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPsPPSAFPTVTTVWQDSDRYHPKPVLHMAsPEQHPADLNRsYDKSADPMGKSESAIEHIDKKLERNLsFEIKKVPLQEGPKsFDGNTLLNRGHAIKIKSAS--SSVVDRTSKPQELSAGALKVDDVSQNSCADCSAAHSHRAAE-SSEESQSNSHtPPRPDCLPLDKKGHVTWSLHGPENAtPVPDsPDGKsPDNHsQTLKTVSSTPNSTAEEEAHDLTEHHNSsPLLKAPLsFtNPLHsDDsDsDGGssDGAVTRNKTSIstASAtVsPASSAESACtRRVLPMSIARQEVAGTPHSGAEKDADVsEEsPPPLPERTPESFVLAD---MPVRPEWHELPNQEWSEQRESEGLTTSGNEK--HDAGGIHTEAsADsPPAFSDKKDQItKsPAEVtDIGFGNRCGKPKGPREPPSEWT
PTP-PEST rat	MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPRAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCENEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKITDG-NEISTGNMVSSIDSEKQDsPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDSDRYHPKPVLHMAsPEQPPTDLNRNYDKSADLMGRSESAVEHTDKKLEQNLsFEIKKVPLQEGPKsFDGNTLLNRGHAIKIKSAS--SSVVDKSSKPQELSSGDLKVHDVSQNSCADCSASHLDNAPE-SSEES-QNSHTPPRPDCLPLDKKGHVTWSLHGPENATPVSDS-----PDNHSQTLKTVSSTPNSTAEEESHDLTEHHNSSPLPRAPLSFTNPLHsDDsDsDEGNSDGAVTKNKTSISTASATVSPASSTESACTRRVLPMSIARQEMAGRRHsGAEKDADVSEEsPPPLPERTPESFVLAD---MPIRSDWHELPSQECSEHRESEGLITSGNDK--HDAGVSHTA---ACSPTFSDKKEEITESLTEVTDIGFGNRCGKPKGPRDPPSEWT
PTP-PEST cow	MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLFGEDPITFAPFKISCEAEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGTQKITDGVNEVNTENMISSTDHDKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQPSTDLNRNYSKSMELTGKNESTIDQIDKKLERNLsFEIKKVPLQEGPRSFDGNTLLNRGHAIKIKSASASPCTVDKISKSQELSSRDLKVDDISQNSCVDCNATQSNKDPIILPEASQKNSDTPPRPDHLPLDGKGHLTWSFHGPENTLPMPDSSEGKSSDIHCQTMKTVSSTPSPTIQVETHDLADHHDSSPLFRAPLSFTNPLHSDDSDSDERNSDGSVTKNKTSISTASATVSAAT--SSISTRKVLPMSIARHDIAGTIHSGAEKDVDVSEDSPPPLPERTPESFVLANEHNTSVRAEWSELQNQEQSEQKNPEGLITSGSETCDHPAQGIHTETCTECPPTVSNKKDQLSEGPTEATEIGFGNRCGKPKGPRDPPSEWT
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Consensus	MEQVEILRRFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIDPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASASPCIADKISKPQELS-SDLNVGDTSQNSCVDCSATQSNKVSVTPPEESSQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETHDLVDHDNSSPLFRAPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHTEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT