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HIF2A human	MTADKEKKRsssERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLkNGSGFGKKSKDMSTERDFFMRMKCTVTNRGRtVNLk K186-ac K186-ub SATWk K191-ac K191-ub VLHCTGQVKVYNNCPPHNSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTkSHQNLCTkGQVVSGQYRMLAKHGGYVWLETQGtVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSGKGAVsEk K385-ac K385-ub SNFLFTkLkEEPEELAQLAPtPGDAIISLDFGNQNFEESSAYGKAILPPsQPWATELRSHSTQSEAGSLPAFTVPQAAAPGSTTPSATSSSSSCSTPNsPEDYYTSLDNDLkIEVIEkLFAMDTEAkDQCSTQTDFNELDLEtLAPYIPMDGEDFQLSPICPEERLLAENPQSTPQHCFSAMTNIFQPLAPVAPHsPFLLDKFQQQLESkKTEPEHRPMSSIFFDAGSKASLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLG-----PPVsPPHVSTFKTRSAk K685-ac K685-ub GFGARGPDVLsPAMVALSNKLKLKRQLEYEEQAFQDLSGGDPPGGSTSHLMWKRMkNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAIsPGENsKSRFPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELTRYDCEVNVPVLGSSTLLQGGDLLRALDQAT
HIF2A mouse	MTADKEKKRsSsELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAIsFLRTHKLLSSVCSENEsEAEADQQMDNLyLKALEGFIAVVtQDGDMIFLsENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKNGSGFGKKSKDVSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNNCPPHSSLCGSKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSrHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSDDVAVTEKSNYLFTKLKEEPEELAQLAPTPGDAIISLDFGSQNFDEPSAYGKAILPPGQPWVSGLRSHSAQSESGSLPAFTVPQADTPGNTTPSAS-SSSSCSTPSSPEDYYSSLENPLKIEVIEKLFAMDTEPRDPGSTQTDFSELDLETLAPYIPMDGEDFQLSPICPEEPLMPESPQPTPQHCFSTMTSIFQPLTPGATHGPFFLDKYPQQLESRKTESEHWPMSSIFFDAGSKGSLSPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWPVGDQSAESLGALPVGSSQLEPPSAPPHVSMFKMRSAKDFGARGPYMMSPAMIALSNKLKLKRQLEYEEQAFQDTSGGDPPGTSSSHLMWKRMKSLMGGTCPLMPDKTISANMAPDEFTQKSMRGLGQPLRHLPPPQPPSTRSSGENAKTGFPPQCYASQFQDYGPPGAQKVSGVASRLLGPsFEPYLLPELtRyDCEVNVPVPGsSTLLQGRDLLRALDQAT
HIF2A rat	MTADKEKKRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKTGSGFGKKNKDRSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNNCPPHSSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELVGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVVYNPRNLQPQCIMCVNYVLSEIEKNDVVVSMDQTESCSSHTLMAMNSIFDTSDDVALSEKSNYLFTNLKEEPEDLAQLAPTPGDAIISLDFGSQNFDESSTYGKAILPPGQPWATELRSHSAQSESRSLPAFTVPQAGSPGNATPSAT-SSSSCSTPSSPEDYYSSLENHLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEEPLVPESPQPNPQHCFSTMSSIFQPLTPGASQGTFFLDKYPQQLESRKTESEHWPMSTIFFDAGSKGSLPPCCGQASTPLSSMGGRSNTPWPPDPPLHLGPTKWSVGNQSAEPLGPLPLGTSQLEPPSTPPHVSMFKMRSAKDFGARGPYMMSPAMIALSNKLKLKRQLDYEEPAFQDTSGGDPPGTSSSHLMWKRMKSLMGGTCPLMPDKTVSASMAPDEFTQKSMRGLGQPLRHLPPSQPPSTRSPGENAKSGFPPQCYASPFQDYSPPGAQKGSGVASRLLGPSFEPYLLPELTRYDCEVNVPEPGSSTLLQGRDLLRALDQAT
	*************:*************************************************************************************************************************************:**:*******:**.*************************************:********:****:***********************************************:**:************************************************************:***************************:*******:::::*********:*:::*::****:***:******:******************:***:*:*:********:***:::*****:***::**********::**::****:.********:******:**:*.***************::*::******:***************************:*.:*:**::******:*::*****:*:*.:::*:***::*****:***:**:***:********:**:*******************:********:*****:**:*::*.**::*:*.::::**::*****:**:****:******:::****:************:***:****:*******:*:*********:*:**:*******:.**::::*:***::*****:******::****::*:***:*::*******:::***::::*:*:**:**********:****************::********:**********
Consensus	MTADKEKKRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKNGSGFGKKSKDRSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVYNNCPPHSSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSDDVAVSEKSNYLFTKLKEEPEELAQLAPTPGDAIISLDFGSQNFDESSAYGKAILPPGQPWATELRSHSAQSESGSLPAFTVPQAAAPGNTTPSAT-SSSSCSTPSSPEDYYSSLENDLKIEVIEKLFAMDTEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEEPLLPESPQPTPQHCFSTMTSIFQPLTPGAPHGPFFLDKYPQQLESRKTESEHWPMSSIFFDAGSKGSLPPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQSAEFLGALPLGSSQLEPPSAPPHVSMFKMRSAKDFGARGPYMMSPAMIALSNKLKLKRQLEYEEQAFQDTSGGDPPGTSSSHLMWKRMKSLMGGTCPLMPDKTISANMAPDEFTQKSMRGLGQPLRHLPPPQPPSTRSPGENAKSGFPPQCYASQFQDYSPPGAQKVSGVASRLLGPSFEPYLLPELTRYDCEVNVPVPGSSTLLQGRDLLRALDQAT