Multiple Sequence Alignment:
dUTPase Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250   )
           |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |   
dUTPase human MTPLCPRPALCYHFLTSLLRsAMQNARGARQRAEAAVLSGPGPPLGrAAQHGIPRPLssAGRLsQGCrGASTVGAAGWKGELPkAGGsPAPG-PEtPAIsPSKRARPAEVGGMQLrFARLSEHAtAPtrGSARAAGYDLYSAYDYTIPPMEkAVVkTDIQIALPsGCyGRVAPRSGLAAkHFIDVGAGVIDEDyRGNVGVVLFNFGkEkFEVKKGDrIAQLICErIFYPEIEEVQALDDtErGsGGFGstGkN
dUTPase iso2 human ----------------------------------------------------------------------------------------MpCs-EEtPAIsPskRARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGkN
dUTPase mouse ------MPL-----LSVLLRARLQA--------------------------ALLRGRALGSARSRSCRGSR--GAPAGSAR------------ADAAAVSASkRARA--EDGASLRFVRLSEHATAPTRGSARAAGYDLFSAYDYTIsPMEKAIVkTDIQIAVPSGCYGRVAPRSGLAVkHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERISYPDLEEVQTLDDTERGsGGFGSTGkN
dUTPase rat ------MPL-----LCALLRSRLQP--------------------------SLLRSLTLTSAQSLSCGGSR--GVRTWSART-------GPGACADPAVSVSKRARA--EDDASLRFVRLSEHATAPTRGSARAAGYDLYSAYDYTIPSMEKALVkTDIQIAVPSGCYGRVAPRSGLAVkHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERILYPDLEEVQTLDNTERGSGGFGSTGKN
dUTPase iso2 rat ------------------------------------------------------------------------------------------MPCSEDPAVSVSKRARA--EDDASLRFVRLSEHATAPTRGSARAAGYDLYSAYDYTIPSMEKALVKTDIQIAVPSGCYGRVAPRSGLAVKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERILYPDLEEVQTLDNTERGSGGFGSTGKN
        ...     ...........                          ....................  ........        .....:::*:*:*****:..:::::***:*********************:*******::****:********:***************:***********************************************.**::****:**:**************
Consensus ------MPL-----L--LLRSRLQ----------------------------LLR-L-L-SA-S-SCRGSR--GA--WSAR---------PG-AEDPAVSPSKRARA--EDGASLRFVRLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKALVKTDIQIAVPSGCYGRVAPRSGLAVKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERILYPDLEEVQTLDDTERGSGGFGSTGKN
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.