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USP11 human	MAVAPRLFGGLCFRFRDQNPEVAVEGRLPIsHsCVGCRRERTAMATVAANPAAAAAAVAAAAAVTEDREPQHEELPGLDSQWRQIENGESGRERPLRAGESWFLVEkHWYKQWEAYVQGGDQDSSTFPGCINNATLFQDEINWRLKEGLVEGEDYVLLPAAAWHYLVSWYGLEHGQPPIERkVIELPNIQkVEVyPVELLLVRHNDLGKSHTVQFSHTDSIGLVLRTARERFLVEPQEDTrLWAk K245-ac K245-ub NSEGSLDRLYDTHITVLDAALEtGQLIIMEtRKKDGTWPSAQLHVMNNNMSEEDEDFkGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMkGEIAEAYADLVkQAWSGHHRSIVPHVFk K383-m1 K383-ub NKVGHFASQFLGyQQHDSQELLSFLLDGLHEDLNRVKKkEYVELCDAAGRPDQEVAQEAWQNHkRRNDsVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPISHkRVLEVFFIPMDPRRKPEQHRLVVPKKGKISDLCVALSkHTGISPERMMVADVFSHRFYKLYQLEEPLSSILDRDDIFVYEVSGRIEAIEGsREDIVVPVyLRERTPARDYNNsyyGLMLFGHPLLVSVPRDRFTWEGLYNVLMYRLSRYVTKPNsDDEDDGDEKEDD------------EEDkDDVPGPstGGsLrDPEPEQAGPSSGVTNRCPFLLDNCLGTSQWPPRRRRkQLFTLQTVNSNGTSDRtTsPEEVHAQPyIAIDWEPEMkKRYYDEVEAEGYVkHDCVGYVMkKAPVRLQECIELFTTVETLEKENPWYCPSCkQHQLATkKLDLWMLPEILIIHLKRFSYTkFSREkLDTLVEFPIRDLDFSEFVIQPQNESNPELYkYDLIAVSNHYGGMRDGHYTTFACNkDSGQWHYFDDNSVSPVNENQIESkAAyVLFYQRQDVARRLLsPAGssGAPAsPACssPPssEFMDVN
USP11 mouse	-------------------------------------------MAAVAADPAAA-----AVPASAEDRDTQPEAMPDLDEQWRQIGN---GRERPLRAGESWFLVEkHWYKQWEVYVKGGDQDASTFPGCINNAGLFEDQISWHLRERLLEGDDYVLLPAPAWNYMVSWYGLMDGQPPIERKVIELPGIRKVEVYPLELLLVQHSDMETALTIQFSYTDSVELVLQTAREQFLVEPQEDTRLWTkNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMN-NIPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDsVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFsHRFyKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTsDEDD-GDEKVDEDEDEDVEDDsSSEEEKEEMSAPTVNDGTREAEQEQAGTSSGVTERCPSLLDNSLRASQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEMQTQPYIAMDWEPDMKRRYYDEVEAEGYVKHDCVGYMLKKsPVQLKECIKLFtTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSkISREkLDTLVQFPIRDLDFSEFVIKPKNESSPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQS-QTSSSDTPAsPVSSSTPNSDIMDIN
USP11 rat	-------------------------------------------MAAVAADPAAA-----AVPASAEDRETQPEAMPDLDQQWRQIGN---GRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGSINNSGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLKDDQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYSDSVDLVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMN-NMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDD-GDEKGDENEDEDVEDDSSSEEEKEEMSGPTDNDGTQESEQEQAGTSSGVTGRCPSLLDNSLHTSQWPPRRRRKQLFTLQTVNSNGTSDRTTsPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKkNPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQS-QtASSETPTsPASSSTPNsDIMDVN
	...........................................**:***:****.....*::*::***::*:*::*:**.*****:*...************************:**:*****:*****:***::**:*:*:*:*:*:*:**:*******:**:*:******.::************:*:******.*****:*:*:::::*:***::**:.***:****:************:**********::*:**:***:******:*****:**********::**.*:::*****:*************************************:****************:**********:***:******:************************************************::*****:*****************************************************::::*******:************:******:*********:**:::*::*:****************:***:************:****::****:*************:**********:***************:******:************:**::*.****.*:.:::::::::::**:*:::::*:.:::::::*:****:*****.***:****:*.:********************************:::*****:****:**:*******************::**:**:*:***:****************:*******************:*********::*:*********:*************:*:***:*:****************************************************************:**::.:::**.:*:**::**:*:*::**:*
Consensus	-------------------------------------------MAAVAADPAAA-----AVPASAEDRETQPEAMPDLDQQWRQIGN---GRERPLRAGESWFLVEKHWYKQWEAYVKGGDQDASTFPGCINNAGLFEDQISWHLRERLVEGDDYVLLPAPAWNYLVSWYGLEDGQPPIERKVIELPGIRKVEVYPIELLLVQHSDMETALTIQFSYTDSVDLVLQTAREQFLVEPQEDTRLWTKNSEGSLDRLCNTQITLLDACLETGQLVIMETRNKDGTWPSAQLCGMN-NMPDEDEDFQGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNRYLEELNFRNPLGMKGELAEAYADLVKQTWSGYHRSIVPNVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCNGAGRPDLEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPVCSRRVLEVFFVPMDPRRKPEQHRVVVPKKGNISDLCVALSTHTSVAPDKMIVADVFSHRFYKLYQLEDPLSGILDRDDIFVYEVTGRIEPVEGSRDDIVVPVYLRERTPSRDYNNSYYGLILFGHPLLVSVPRDRFSWEGLYNILMYRLSRYVTKPTSDDDD-GDEKEDENEDEDVEDDSSSEEEKEEMSGPTDNDGTREAEQEQAGTSSGVTNRCPSLLDNSLRTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEAQTQPYIAMDWEPEMKRRYYDEVEAEGYVKHDCVGYMLKKAPVQLKECIKLFTTVETLEKENPWYCSSCKQHQLATKKLDLWMLPEVLIIHLKRFSFSKFSREKLDTLVQFPIRDLDFSEFVIKPKNESAPDLYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVGRRQS-QTASSDTPASPASSSTPNSDIMDVN