Multiple Sequence Alignment:
MAEA	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 )
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MAEA human	MAVQESAAQLSMTLKVQEyPTLkVPYEtLNkRFRAAQk K38-ac K38-ub NIDRETsHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLkRkAVESIQAEDESAkLCKRRIEHLk K107-m1 K107-ub EHSSDQPAAASVWkRKRMDRMMVEHLLRCGYYNTAVkLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNkSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARkHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRM-----LIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYkEDGSSk sPDCPVCSRSLNk K323-ub K323-sm LAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDkVVCPRTkEVFHFSQAEKVYIM
MAEA iso2 human	MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVkLARQSGIE-----------------------------------------SCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRTCTVADLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM
MAEA mouse	MAVQESAAQLSMTLKVQEyPTLKVPYETLNkRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASMWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEEsLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFSQAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPARWRM-----LIQQFRYDNYRLHQLGNSSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM
MAEA rat
	*********************************************************:******************************************************:*****************************:::::::::::::::::::::::::::::::::::::::::***********:*************************:*********************:.....*************:***************************************************************************************************************
Consensus	MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRM-----LIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.