Multiple Sequence Alignment:
EEA1 Download MSA
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EEA1 human MLRRILQRtPGRVGsQGsDLDssAtPINTVDVNNESSSEGFICPQCMKsLGsADELFkHYEAVHDAGNDsGHGGESNLALkRDDVTLLRQEVQDLQAsLkEEKWYSEELKKELEKYQGLQQQEAKPdGLVTDSSAELQsLEQQLEEAQTENFNIKQMkDLFEQk
AAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNkEATVIQDLKTELLQRPGIEDVAVLKkELVQVQtLMDNMtLEREREsEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVyVQELQKLKssVNELtQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLsAsETSLHRIHVELSEKGEATQKLKEELsEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSkLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEkEREDLYAkIQAGEGEtAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHkQAQENLHDQVQEQKAHLRAAQDRVLsLEtSVNELNsQLNESkEKVsQLDIQIkAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNtDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKKILKQDFETLSQETkIQHEELNNRIQTTVTELQKVKMEkEALMtELstVKDKLsKVSDSLKNSKSEFEKENQKGkAAILDLEKTCkELKHQLQVQMENtLKEQKELKKSLEKEKEAsHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENkLQQQLTQAAQELAAEKEKIsVLQNNyEKsQEtFkQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSkLAEIEEIkCRQEkEITkLNEELKSHKLESIKEItNLKDAKQLLIQQKLELQGkADSLkAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGtVKKEWQSSQRRVsELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTkVLELQRkLDNTTAAVQELGRENQSLQIkHTQALNRKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALtPSSKKPVRVCDACFNDLQG
EEA1 mouse MFRRILQRtPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPQCMKSLGsADELFKHYQAVHDAGNDsGHGGEAGLALTRDDITLLRQEVQDLQASLkEEKWYSEELKKELEkYQGLQQQEAKSDGLVTDSSAELQALEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKsKyDEEKSLRAAAEQKVTHLTEDLNKQTTVIQDLkTELLQRPGIEDVAVLKkELVQVQtLMDNMtLEREREsEKLKDECKKLQSEHAHLEATINQLRSELAKGPQEVAVYVQEIQKLKGSINELTQKNQNLTEKLQKKDLDYTHLEEKHNEESASRKTLQASLHQRDLDCQQLQARLTASESSLQRAQGELSEKAEAAQKLREELREVESTRQHLKVEVKQLQQQREEKEQHGLQLQGEVSQLHCKLLETERQLGEAHGRLKEQRQLSSEKLMEKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSATAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKGKESVSLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLTEkLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKAAQRADLQNHLDTAQHALQDKQQELNKVSVQLDQLTAKFQEKQEHCIQLESHLKDHKEKHLsLEQKVEDLEGHIKKLEADALEVKASKEQALQSLQQQRQLSTDLELRNAELSRELQEQEEVVSCTKLDLQNKSEILENIKQTLTKKEEENVVLKQEFEKLSQDSKTQHKELGDRMQAAVTELTAVKAQKDALLAELSTTKEKLSKVSDSLKNSKSEFEKENQkGKAAVLDLEKACkELKHQLQVQAESALKEQEDLKKSLEKEKETSQQLKIELNSVKGEVSQAQNTLKQKEkDEQQLQGTINQLKQSAEQKKkQIEALQGEVKNAVSQKTVLENkLQQQSSQAAQELAAEKGKLSALQSNYEKCQADLKQLQSDLYGKESELLAtRQDLKSVEEKLTLAQEDLISNRNQIGNQNKSIQELQAAKASLEQDSAKKEALLKEQSKALEDAQREKSVKEKELVAEKSKLAEMEEIKCRQEKEITKLNEELKSHKQESIKEITNLKDAkQLLIQQKLELQGRVDSLKAALEQEKESQQLMREQVKKEEEKRKEEFSEKEAKLHSEIKEKEAGMKKHEENEAKLTMQVTTLNENLGTVkKEWQSSQRRVsELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTkALELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSTKNALTPSSKKPVRVCDACFNDLQG
EEA1 rat MFRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPQCMKSLGsADELFKHYQAVHDAGNDSGHGGEASLALTRDDIALLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKSDGLVTDSSAELQSLEQQLEEAQTENFNIKQMkDLFEQkAAQLATEIADIKSkYDEEKGLRAAAEQKATHLTEELSKQTTVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSEHANSEATINQLRSELAKGPQEVAVYVQEIQKLKGSVNELTQKSQTLMEkLQKKDLDYTHLEEkHNEEALSRKNTQAALHQRDLDCQQLQARLTASEGSLQRIQGELREKGEAAQKLkEELREVETKHQHLkVEFKQLQQQREEKEQHGLQLQGEVSQLHSkLLETERQLGEAHGRLKEQRQLSSEKLMDkEQQVADLQLkLSRLEEQLKEKVTNSTELQHQLEkSKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQkIQNLEALLQkSkENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLMEKLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKVSAQLDQVTAKFQEKQEHCTQLESHLKDYKEKHLSLEQkAEDLEGQIKKLEANNLEVkASREQAVQSLQQQRQLSTDLELRNAELRKQLQEQKEVVSHTkLDLQNkSEALENIKQTLTKKEEEKVVLkQEFEKLSQDSEAQHKELSDRMQAAITELMVMTAQKDALLAELSTTKGKLSKVSDSLQTSRSEFEKESQKGKAAVLDLEKACKELkHQLQQQTESALKEQSELKKSLEKERETSQQLMIELNSVKGEVTQAQNTLKQKEkEEQQLQGNINQLKQATEQKKKQMEALQGELkNVTSQKAQLESkLQQQAAQAAQELAVEKGKLSALQSTYDKCQADLQQLQSDLYGKESELLATRQDLKCVEEKLALAQEDLISNRNQIGNQNKSIQELQAAKAALEQDLAkKEEVLKEQSKALQDAQREKSVKEKELVTEKSKLAEMEEIkCRQEkEIAkLKEELkSHkQESIKEVTNLkDAkQLLIQQkLELQGkVDSLkAALEQEkERQQLMREQMRKEEEKRKEEFSEKEAKLHSEIKEKEAGVKKHEENEAKLTMQVTTLNENLGTVKKEWQSSQRRVsELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLkGEGEIEkLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG
  *:**********************************************************:**************:.***:***::***************************************:************:*******************************************::**:*****:*:***:*:*::********************************************************::*.:****:*******************:****:*:******:*:*:*:*:**::***:********::*:*:.**:***:********:**:***.**:*:::**:**:**:***:***:***::.****:*:******************:*::***:****************************:*********************************:*:*************:**********************************:**::********************************:**:*:***:*************:****************************:**:*******************************:**************:***********:::****:***:*:*****.*******::***:******:*:***:******::******:***:*:*******:******::**:::*::::*:**.*:****:***:**:***:***:***:::***:**:***::::**:**.:*:*:::***.:::::*:**::****:*.*********::*:******:******:*****:*********:*:*::****.:********:*:*:**::****:::::.********:**:******:**:***::******:******:*::::**:.**:*****::*******:**:*:*:**::*:*:*::::*****:**:************:*****:******************:****::***:****:****:.*:*::***:*:*:***:******:*******:***********:**:*******:*****:*******************::******:****:.**::::*::****::*:**:**************:*:*************:*:*******************************************************************:**********************************************:***:**********************:************************
Consensus MFRRILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPQCMKSLGSADELFKHYQAVHDAGNDSGHGGEANLALTRDDITLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKSDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEEKSLRAAAEQKVTHLTEELNKQTTVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSEHANSEATINQLRSELAKGPQEVAVYVQEIQKLKGSVNELTQKNQTLTEKLQKKDLDYTHLEEKHNEESASRKNIQAALHQRDLDCQQLQARLTASEGSLQRIQGELSEKGEAAQKLKEELREVETKRQHLKVEFKQLQQQREEKEQHGLQLQGEVSQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHALQQQLTQLTEKLKNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKVSAQLDQVTAKFQEKQEHCIQLESHLKDYKEKHLSLEQKAEDLEGQIKKLEADALEVKASKEQALQSLQQQRQLSTDLELRNAELSKQLQEQKEVVSCTKLDLQNKSEALENIKQTLTKKEEEKVVLKQEFEKLSQDSKAQHKELNDRMQAAVTELQAVKAQKDALLAELSTTKDKLSKVSDSLKNSKSEFEKENQKGKAAVLDLEKACKELKHQLQVQAESALKEQEELKKSLEKEKETSQQLKIELNSVKGEVIQAQNTLKQKEKEEQQLQGNINQLKQSAEQKKKQIEALQGELKNAVSQKTQLENKLQQQAAQAAQELAAEKGKLSALQSNYEKCQADLKQLQSDLYGKESELLATRQDLKSVEEKLALAQEDLISNRNQIGNQNKSIQELQAAKAALEQDSAKKEAQLKEQSKALQDAQREKSVKEKELVAEKSKLAEMEEIKCRQEKEITKLNEELKSHKQESIKEITNLKDAKQLLIQQKLELQGKVDSLKAALEQEKERQQLMREQVKKEEEKRKEEFSEKEAKLHSEIKEKEAGMKKHEENEAKLTMQVTTLNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQNCMSCGKCFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFNDLQG
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.