Multiple Sequence Alignment:
MBD1 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580       590       600       610       620       630       640       650       660       670        )
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MBD1 human MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQsPTGDRIRSkVELTRyLGPACDLTLFDFKQGILCYPAPkAHPVAVASkKRKKPSRPAKTRKRQVGPQSGEVRkEAPRDEtKADtDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSkMAARRRPGAQPLPPPPPsQsPEPtEPHPRALAPsPPAEFIYYCVDE--DELQPYTNRRQNRkCGACAACLRRMDCGRCDFCCDKPKFGGsNQKRQKCRWRQCLQFAMkRLLPsVWsEsEDGAGsPPP---YRRRKRPSSARRHHLGPTLkPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGAsSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVkQEkADtQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVkQEPPDPEEDKEENKDDSAskLAPEEEAGGAGtPVItEIFSLGGTRFRDtAVWLPrSkDLKKPGARKQ--------------------------------------------------
MBD1 iso2 human MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEP-------------------------QPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPP---YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ----------------------------------------------AVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPSLQGRHSGREDGCKVWETEDTVEPTSTSWNPRGWPGTHVSLsPPPASMMWVSCRRSWCPSSQS
MBD1 iso4 human MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPsPPAEFIYYCVDE--DEL--------------------------------------------------------KRLLPSVWSESEDGAGSPPP---YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ----------------------------------------------AVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKPGARKQ--------------------------------------------------
MBD1 iso5 human MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFkS-------------------------------------------------RGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDE--DELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPP---YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKPGARKQ--------------------------------------------------
MBD1 iso9 human
MBD1 iso10 human MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKS-------------------------------------------------RGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPsPPAEFIYYCVDE--DEL-PYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPP---YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRYYHLALDWKCNCGY---------HLCCRSVL----------VP-------------------
MBD1 iso11 human MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPsPPAEFIYYCVDE--DEL--------------------------------------------------------KRLLPSVWSESEDGAGSPPP---YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQ----------------------------------------------AVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRAGTREGKMDVKCGR---------PRTQWsPRARAGTHEDGLEPMSVSHHLQLR---------
MBD1 mouse MAESWQDCPALGPGWKRRESFRKSGASFGRSDIyYQsPTGEKIRSKVELTRYLGPACDLTLFDFRQGTLCHPIPKTHPLAVPSKKKKKPSKPAKTKKQQVGLQRSEVRIETPQGEYKAPTATALASLSVSASASSSASASASASSHAPVCCENCGIHFSWDGVKRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGDCAACLVKEDCGVCSTCRLQLPSDVASGLYCKCERRRCLRIMEKSRGCGVCRGCQTQEDCGHCCICLRSPRPGLKRQWRCLQRRCFWGKRDSSKRG--SKVASQRHSQAPPLPPHPASQYTEPTELHISDIAPTSPAEFIYYCVDEDEDELQPYTNQRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGGNQKRQKCRWRQCLQFAMKRLLPSAGSGSGEGAGLRPYQTHQTHQKRPASARQLQLSsPLKAPWAVVTAPPGPVRDSRKQQAGRGSVLPQPDTDFVFLQEGTSSAMQMPGTAAASTEVPVQAAQCSAPSWVVALPQVkQETADAPEEWTAVTTFLTSSTLQSGFPSKAADPDLsPVKQEPPGPEEDGEEK-KDDVSETTPAEEIGGVGTPVITEIFSLGGTRLRDAEAWLPRLHKLLAVNEKEY---FTELQLKEEVL------------------------------------
MBD1 rat MAEAWQDCPALGPGWKRREAFRKSGASCGRSDIYYrSPTGEKIRSKIELTRYLGPACDLTLFDFRQGILCHPVPKTHPLAVPSKKKKKTSKPAKAKKQQVGPQRSEVRKETPREGNKVAPATALLPVTASAPAPVPVPVSAPAPAPAPLCCENCGIHLSWDGIKRERRRTLCKDCRAQRIAFNREQRMFKRVGCGECTACLVKEDCGVCSICCLQLPNDVASGLFCKCEQRRCLRIVEKG-------------------------------------------KYDHSKRG--PRVASRRHSRAPPLPPHAASQHPEPTELHISDQTPTAPAEFVYDCVEEDE----------------------------------------------------------LKRLLPSIGPGSEEEARLLP---HHTHQKRSASTRQLQLSsPLKAPLAVVTTPPGPVQDSGKRQAGSGFVLPQPDTDLVYLQEGTSSLMQVPGPAAASTENPAQETQGSAPGWVVALPQVKQEKADAPEEWTAVTTFLTSSTVQPGFLSKASGLDPPPVKREPPGPEEDGEENKEDDVSESAPAEEIGGIGTPVITEIFSLGGTRLRDAEAWLPRLHKLLAVNENEY---FTELQLKEEIL------------------------------------
  ***:*:*************:******::****:**:****::****:*****************:**:**:*:**:**:**:***:**:*:***::*:***:*::***:*:*::::*::::*                  *:*:::**:*******::*:**::*:*::*********************:::::.::::.:.::::.::.:.::::.::::::.::::.::::::.:..:::::::::::::::::::::::::::::::::::::::::::*::::*:*:::::*::*:::*:****:::**::****:::::.:::::::::::::::  :::........................................................******::::*:::*:::*:   ::::**::*:*:::*:::**:::*::*::*:::::::*::**:*:***:*:**:*:*:**:**::*:**::*****:::*..............................................*:::::::**:***:****:**:::*::*:::*:**:**:***************:**:::***::..:....:...    ..     . .                .                   
Consensus MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGILCYPAPKAHPVAVASKKRKKPSRPAKTRKRQVGPQSGEVRKEAPRDETKADTDT------------------APASFPAPGCCENCGISFSGDGTQRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWKCVQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFIYYCVDE--DELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKRLLPSVWSESEDGAGSPPP---YRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQEAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQEAQCSGLSWVVALPQVKQEKADTQDEWTPGTAVLTSPVLVPGCPSKAVDPGLPSVKQEPPDPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRLKDLKKPGARKC--------------------------------------------------
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.