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POM121 human	MsPAAAAAGAGERRRPIASVRDGRG--RGCGGPARAVLLGLSLVGLLLYLVPAAAALAWLTVGATAAWWGLSREPRGSRPLssFVRKARHRRPLssFVRKARHRRTLF-AsPLAkSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAAAPEGQDLRDRPGRRPPARPAPRsPPPRsPPPrsPPPsPPTHRAHHVYPSLPTPLLRPSRRPSPrDCGTLPNr R223-m1 R223-m2 FVITPr R229-m1 R229-m2 RRYPIHQAQYSCLGVLPTVCWNGyHKKAVLsPRNSrMVCsPVtVRIAPPDRRFsRsAIPEQIISSTLSsPSSNAPDPCAkEtVLsALk K317-ac K317-ub EkEKKRTVEEEDQIFLDGQENkRRRHDssGsGHsAFEPLVANGVPASFVPKPGsLKRGLNsQssDDHLNkRsRsssMssLtGAyASGIPSSsRNAITSsySSTRGIsQLWk K428-m1 K428-ub RNGPSssPFssPAssRsQtPERPAKKIREEELCHHssSSTPLAADREsQGEKAADttPRKKQN-SNsQstPGssGQRKRKVQLLPsRRGEQLTLPPPPQLGYSITAEDLDLEkkAsLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALsPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATkPQAtsAPsPAPKQSFLFGTQNts--PssPAAPAASSAPPMFKPIFTAPPksEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFF-KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLF-GAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLAT--SAPATSSQPTLTFSNTStPTFNIPFGSSAKsPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMIKVVPAYVPtPIHPIFGGATHSAF-GLKATASAFGAPASSQPAFGGSTAVF-FGAATSSGFGA------TTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSKTPGARQRLQARRQHtRKK
POM121 iso2 human	----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVCSPVTVRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPASFVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQN-SNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTS--PSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFF-KQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLF-GAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLAT--SAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSSFTFGNSAAPAAAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAF-GLKATASAFGAPASSQPAFGGSTAVF-FGAATSSGFGA------TTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSKTPGARQRLQARRQHTRKK
POM121 mouse	MSPAAAAADGGERRRPPLGGREGRSRARGYGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALssFVRDARRHPR-----------PALTAsPPPAKSPVNGSLCEPRsPLGGPDPAELLLMGSYLGKPGPPEPALR---QDPRERPGRRPP--------------ARsPPPASAVQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVItPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCsPVTVRIAPPDskLFRssMsEQILDtTLSsPssNAPDPCAKETVLNALKEKK-KRTVAEEDQLHLDGQENKRRRHDsGGsGHsAFEPLVANGVPAAFVPKPGSLKRsLAsQssDDHLNKRsRTssVssLAsACTGGIPSSSRNAITSSYSSTRGIsQLWKRSGPtssPFssPAssRsQtPERPAKKTREEEPCQQSsSsPPLVtDKEsPGEKVTDTTTGKQQSSWTSPPtPGSSGQRKRKIQLLPsRRGDQLTLPPPPELGYSITAEDLDMERKAsLQWFNKVLEDKPDDASASATDGPPSTSPPFTFTLPAVGPAASPASLPAPSSNPLLESLKKMQESPAP-SSSEPAEAATVAAPsPPKTPSLLAPLVSPLAG---PLASTSSDSKPAATFLGLASASSITPLTDSKSSGVSQAEQSVSTPASTASSPTPKPSMLFGMLSPPASSSSLATPAPACASPMFKPIFPAtPKSESDSPLPSSSSAATTASSSTA-PPTAASTTPTFKPIFDKMEPFTAMPLSTPFSLKQTTATATTTATSAPLFTGLGTATSTVASG-----TAASASKPVFGFGVTTAASTASST----MTSTSQSVLFGGAPPVTTSSSAPALASIFQFGKPLAPAASAAGTSFSQPLASSTQTAAS--NSGFSGFGSTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSSSAKPALPTYPGANSQPTFGATD----GATKPALAPSFGSSFTFGNSVASAPSAAPAP----------------ATFGSAAQPAFGGLKAAASTFGAPASTQPAFGSTTSVFSFGSATTSGFGAAATAATTTQTTNSGSSSSLFGSSAPSPFTFGGSAAPAGSGGFGLS-ATPGTSSTSGTFSFGSGQSGTPGTTTSFG-SLSQNTLGAPSQGSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK
POM121 rat	MSPAAAAADGGERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRGLSSFVRESRRHPR-----------PALTASPLPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALP---QDPRDRPGRRPP--------------SRSPPSSSTAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLFRSPMPEQILSTTLSSPSSNAPDPCAKETVLNALKEKK-KRTVAEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSsDDHLNKRSRtsSVsSLTSTCTGGIPSSSRNAITSSYSSTRGVSQLWKRSGPTSsPFSsPASSRSQTPERPAKKTREEEPCHQSSSSAPLVTDKESPGEKVTDPATGKQQSLWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERRAsLQWFNKVLEDKTDDASTPATDTSPATSPPFTLTLPTVGPAASPASLPAPSSNPLLESLKKMQESPAP-SSSEPPEAATVAAPSPPKTPSLLAPLVSPLTG---PLASTSSDSKPTTTFLGLASASSATPLTDTKAPGVSQAQLCVSTPAATAPSPTPA-STLFGMLSPPASSSSLATPGPACASPMFKPIFPATPKSESDNPLPTSSSAATTTPASTALPTTATATAHTFKPIFESVEPFAAMPLSPPFSLKQTTAPATTAATSAPLLTGLGTATSTVATG-----TTASASKPVFGFGVTTAASTA-ST----IASTSQSILFGGAPPVTASSSAPALASIFQFGKPLAPAASVAGTSFSQSLASSAQTAASNSSGGFSGFGGTLTTSTSAPATTSQPTLTFSNTVTPTFNIPFSASAKPALPTYPGANSQPTFGATD----GATKPALAPSFGSSFTFGNSVASAPSAAPAP----------------AAFGGAAQPAFGGLKASASTFGTPASTQPAFGSTTSVFSFGSATTSGFGAAAA---TTQTTHSGSSSSLFGSSTPSPFTFGGSAAPAGGGGFGLS-ATPGTGSTSGTFSFGSGQSGTTGTTTSFGGSLSQNTLGAPSQSSPFAFSVGSTPESKPVFGGTSTPTFGQSAPAPGVGTTGSSLSFGAPSTPAQGFVGVGPFGSGAPSFSIGAGSKTPGARQRLQARRQHTRKK
	::::::::.:::::::.:..:.::...::.::::.:..:::.:.::.:::::::::::::.:::.::::::::::::.:.::::::..:....           ..:..:...:::.:::.:.:::..:.::::::::::::::::::::.:::.   ::.:.:::::::              .::::.:....:::::::.::::::::::::..::::.:..::::::::::::.:::::.::.::::::::.::::::::::::**************::::**:::***:::*******************:*****:.****:****::*************:*****************:**********:*:*************:**:***::::::*******************:******:**:*********************:****:*::****:**::*:**:***::*::::*:*:.::*::***********:********:********:***********:*::*******::****.*:**:::*:::*:*:*:**:***:::**::*:**:***:***********::*::.:::*:::***::*:*********:**:::::*...:*:*:*:****::*:***::*:*::*:**:*:::::**:.:::::*::*:**:*:.*.***:::::..:**:*:*::::*:*******:*:****::.*:*.::*:::*:::*:::*:*:::*::**:*:*.:::*::::**::**:.****::**:::*:***:***::***:**.:.....:::*****:****:::::*::.**....::::**:.**.***:::::*::**::********:*:::::::*:***:*:::::**:*.::::*****:**:*..*****:**********:********::***::**:*****:**:***::....**:*****************:*:*::::***................::**:*:::**.****:**:**:***:*****::*:**.**:**:*****...   ****:.******:***::**************:*:**::.****:::*:*:****:****:::*:*:*:::*:**:**:::*::****:*:**:*********:*****:::*******:********:*:********:****:*:***************************
Consensus	MSPAAAAADGGERRRPPLGVREGRGR-RGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRGPRALSSFVRDARRHPR-----------PALTASPPPAKSPVNGSLCEPRSPLGGPDPAELLLMGSYLGKPGPPEPALA---QDPRDRPGRRPP--------------ARSPPPSSAAQRVHHVYPALPTPLLRPSRRPPHRDCGPLSSRFVITPRRRYPIQQAQYSLLGALPTVCWNGGHKKAVLSPRNSRMVCSPVTVRIAPPDRRLFRSAIPEQIISSTLSSPSSNAPDPCAKETVLNALKEKEKKRTVAEEDQIHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRGLASQSSDDHLNKRSRSSSMSSLTGACAGGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHQSSSSTPLAADRESQGEKAADTTPRKQQN-SNSQPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPQLGYSITAEDLDLERKASLQWFNQALEDKSDAASNSATDTPPITQPPFTFTLPAAAPAAPPASLLAPSSNPLLESLKKMQEPPALPPCPEPAEAATTAALSPPKTPSLLAPLGLPQSGPPGLLASPSFDSKPPTTLLGLAPAPSMTPATDTKAPGTLQAETATKPQATSAPSPAPKQSFLFGMQNPPASPSSLAAPAAACAPPMFKPIFPAPPKSEKDGPLPPGPSAAATAPSSSALPTTASTTAPTFQPIFSSMEPFAAMPLPAPFFLKQTTAPATAPATSAPLFTGLASATSAVAPGTSASPSTASASKPAFGFGINSAASSAVSTTTSTATAASQPFLFGGAPQASAASFAPALASIFQFGKPLALAASTAGTSFSQSLASAVQTAASSSAADFSGFGSTLATSTSAPATSSQPTLTFSNTSTPTFNIPFGSSAKPALPSYPGANPQPAFGAADGQPPGAAKPALAPSFGSSFTFGNSAAPAAAAAPAPPSMIKVVPAYVPTPIHAIFGGAAQPAFGGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGAAA----TTQTASSGSSSSLFGSSTPSPFTFGGSAAPAGSGGFGINVATPGSSSTSGAFSFGAGQSGSTATSTPFAGGLGQNALGAPGQSSPFAFNVGSTPESKPVFGGTATPTFGQNAPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGSAALSFSIGAGSKTPGARQRLQARRQHTRKK