Multiple Sequence Alignment:
UBLE1A Download MSA
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UBLE1A human MVEKEEA----GGGIsEEEAAQYDRQIrLWGLEAQkRLRAsRVLLVGLkGLGAEIAkNLILAGVkGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVk
VDTEDIEKKPESFFTQFDAVCLTCCSRDVIVkVDQICHkNsIKFFTGDVFGYHGYTFANLGEHEFVEEkTKVAkVsQGVEDGPdtk
RAk
LDsSETTMVkKkVVFCPVkEALEVDWSSEk
AKAALKRTTSDYFLLQVLLKFRTDKGRDPSSDTyEED---SELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMkGNGIVECLGPK
UBLE1A iso2 human MVEKEEA----GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQGTASPR----WPQ-CVRWLEGFWHRKL------------------------------------------------------------------------------
UBLE1A iso3 human MVEKEEA----GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQGPVSAGPSSQQLL-LLRWHEGEWDCGVPWPQVNSR---FGSPRD-------ANCsMPtCIPCPLPs---------------------------------------
UBLE1A mouse MVEKEEAGGGGGGGIsEEEAAQYDRQIRLWGLEAQkRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDPGAQFLIQTGSVGRNRAEASLERAQNLNPMVDVKVDTEDVEKKPESFFTKFDAVCLTCCSRDVIIKVDQICHRNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAkVsQGVEDGPEAk
RAkLDSSETTMVkKKVLFCPVKEALEVDWSGEkAKAALKRTAPDYFLLQVLLKFRTDKGRDPTSESYKED---AELLLQIRNDVFDSLGIsPDLLPDDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ
UBLE1A rat MVEkEEV-SGGGGGISEEEAAQYDRQIRLWGLEAQkRLRASRVLIVGMKGLGAEIAKNLILAGVKGLTMLDHEQVSPEDLGAQFLIRTGSVGQNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTEFDAVCLTCCSKDVIIKVDQICHRNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVTKVSQGVEDGPDAkRAkLDSSETTMVKKKVLFCPVKEALAVDWSGEKAQAALKRTAPDYFLLQVLLKFRTDKGRDPTSDSYSED---AELLLQIRNDVFDSLGVSPDLLPDDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ
  ******:  ..*********************************:**:***************************:***:******:*****:*************************:*********:**********:***:*******:*********************************:**********::*****************:********:****:***:******::******::::::....:::.:..:.*: . :::.....:......:...:.......:.:....:..::..........................................
Consensus MVEKEEA----GGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRTDKGRDPTSDRYEED---AELLLQIRNDVFDSLGISPDLLPDDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGSGIVECLGPQ
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.