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Artemis human	MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVkDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILHHLTTDRNTQIHACRHPkAEEyFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVRTGESSYRACFsFHSSySEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEILKPLCRSSQSTEPKYKPLGKLKRARtVHRDsEEEDDYLFDDPLPIPLRHKVPYPETFHPEVFSMTAVSEKQPEKLRQTPGCCRAECMQSSRFTNFVDCEESNSESEEEVGIP-ASLQGDLGSVLHLQ---KADGDVPQWEVFFkRNDEITDEsLENFPSSTVAGGsQ----------------SPKLFSDSDGESTHISsQNSsQSTHITEQGsQGWDsQSDTV----LLSSQERNS----GDITSLDKADYRPTIKENIPASLMEQNVICPKDtYSDLKsRDKDVtIVPSTGEPTTLssETHIPEEKSLLNLSTNADsQsssDFEVPstPEAELPKREHLQYLYEKLAtGESIAVkKRKCsLLDt-
Artemis mouse	MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRIITIEIETPTQISLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWVTRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMPDILHHLTTDRNTQIHACRHPKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVRTGESSYRACFSFHSSFSEIKDFLSYICPVNVYPNVIPVGLTVDKVMDVLKPLCRSPQSVEPKYKPLGKLKRARtIHLDsEED-DDLFDDPLPTPLRHKVPYQLTLQPELFSMKALPLDQPE-LRQSPGGCKAESVWSPSLANFIDCEESNSDSGEELETPPPSLQGGLGPSTLVQQNADPDVDIPQWEVFFKRRDEITGECLEHLPSSIETGGsQ--SPKLCSDSPKLCSDSPKLCSDSDGDSTHISSQNSSQSTHITDQGSQGWDSQCDTV----LLSSQEKSG----GDSTSLNKGAYKPKLKESISASQIEQDALCPQDTHCDLKSRAE-VNGAPCLVELDTLSGRKSPPEKTL--LSSTRADSQSSSDFEIPSTPEAELPTPEHLQCLYRKLATGQSIVVEKRKCsLLDS-
Artemis iso2 mouse	MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRIITIEIETPTQISLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWVTRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMPDILHHLTTDRNTQIHACRHPKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVRTGESSYRACFSFHSSFSEIKDFLSYICPVNVYPNVIPVGLTVDKVMDVLKPLCRSPQSVEPKYKPLGKLKRARTIHLDSEED-DDLFDDPLPTPLRHKVPYQLTLQPELFSMKALPLDQPE-LRQSPGGCKAESVWSPSLANFIDCEESNSDSGEELETPPPSLQGGLGPSTLVQQNADPDVDIPQWEVFFKRRDEITVDTMIRtPRPRKMKGCGQWSLKMLLQNLEI-----------------------QEEKHI--FENRGWKMAGQVKGSCGLLEGQSSLPTFKLATSLASNSSFWPPWHLHSHAHTQIFT-----------FKKK-----------------------TKTL--L-------------------------------------------------------
Artemis rat	MSsFQGQMEEYPtIsIDRFDRENLKARAYFLSHCHKDHMKGLRAPsMKRRLECSLKVFLYCSPVTKELLLTSPKYKFWENRIIAIEIETPTQVSLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEVSRMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREECLRGVLELVRSWITRSPKHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMPDILHHLTTDRNTQIHACRHPKAEEYFQWNKLPCGMASKTKTVLHTISIKPSTMWFGERTRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYICPVNAYPNVIPIGLTVDKVMDFLKPLCRSSQCAEPKYKPLGkLKRARTVHLDsEED-DDLFDDPLLTHSRRKVPYQVTLHPEVFSMKALPLDQPE-LGQSPGCCKAESMPSPSLANFVDCDESNSDSEGELETP-PSLQGGLGPTTLPQQNADPDVDVPRWEVFFKRKDEITDECLENLPSSIETGGSQ--SPKRFSD-------SPKLGSDSDGESTHISSQNSSQSTHITDQGSQGWDSQCDTV----LLSSQEKSG----GDSTSLNKDTYKPKPKDSISASQIEQNALCPQDTHCDLKSGAE-VNGVPCIEEPDTVSGRKSSPEKTS--LTSTQADSQSSSDFEIPSTPEAELPKPEHLQFLYGKLATGESIVLKKENVHSQIFK
	****:***:***************:********************::**********:*****************:**::***:********:************:********************:*************:**::***********************************:**:*:*******:****.******************************:*****:***:***********************:***:*****::*.::::**:*************:***********************:*********:****:******:*:*:***:::*******:*::***************:*:****: *:******::::*:****:.*::**:***:*::::*** *:*:**:*:**::.*::::**:**:****:*::*:::*.:****:**:.::.*:::::*:*:*:*******.****.:.::..*::..::*::  :.:........   ::::.:::::.:::::::::::::**:.::::**:::.:::    **::*:...    ::::::::..:.*..:.:::::::::...::.::..::*:... :..::...:..:.:.....:::::  :.::.::::::::::.:::::::::..::::.::.:::::.:::..:........
Consensus	MSSFQGQMAEYPTISIDRFDRENLKARAYFLSHCHKDHMKGLRAPSLKRRLECSLKVFLYCSPVTKELLLTSPKYRFWENRIITIEIETPTQISLVDEASGEKEEVVVTLLPAGHCPGSVMFLFQGSNGTVLYTGDFRLAKGEASRMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREQCLRGILELVRSWITRSPHHVVWLNCKAAYGYEYLFTNLSEELGVQVHVDKLDMFKNMPDILHHLTTDRNTQIHACRHPKAEECFQWNKLPCGITSQNKTALHTISIKPSTMWFGERTRKTNVIVRTGESSYRACFSFHSSFSEIKDFLSYICPVNAYPNVIPVGLTVDKVMDVLKPLCRSPQSVEPKYKPLGKLKRARTIHLDSEED-DDLFDDPLPTPLRHKVPYQLTLQPELFSMKALPLDQPE-LRQSPGCCKAESMWSPSLANFIDCEESNSDSEEELETPPPSLQGGLGPSTLVQQNADPDVDIPQWEVFFKRRDEITDECLENLPSSIETGGSQ--SPKRCSD-------SPKLCSDSDGESTHISSQNSSQSTHITDQGSQGWDSQCDTV----LLSSQEKSG----GDSTSLNKAAYKPKHKESISASQIEQNALCPQDTHCDLKSRAE-VNGVPCIEEPDTLSGRKSIPEKTL--LLSTRADSQSSSDFEIPSTPEAELPKPEHLQCLYRKLATGESIVVKKRKCSLLDF-