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HCN2 human	MDARGGGGRPGESPGATPAPG-PPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPEAADEGGPRGRLRSRDSsCGRPGtPGAAstAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSCRGAASGPAPGPGPAEEAGSEEAGPAGEPRGSQASFMQRQFGALLQPGVNkFsLRMFGsQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDyIFLIVEKGIDsEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPRNCWVSINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGtIGKKMyFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLNSGVFNNQENAIIQEIVKyDREMVQQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGsPRLVRRPPPGPAPAAAsPGPPPPAsPPGAPAsPRAPRTSPyGGLPAAPLA--GPALPARRLSRASRPLSASQPSLPHG--APGPAASTRPASSSTPRLGPtPAARAAAPsPDRRDSAsPGAAGGLDPQDSARSRLSSNL
HCN2 mouse	MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPPQPQPPPAPP------PNPTTPSH--------PESADEPGPRARLCsRDsAC----TPGA---AKGGANGECGRGEPQCs---PEGPARGPkVsFSCRGAASGPS----AAEEAGsEEAGPAGEPRGsQAsFLQRQFGALLQPGVNkFSLRMFGSQkAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHkLPADFRQkIHDyYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRkLVAsMPLFANADPNFVtAMLtKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNsILLHKVQHDLSSGVFNNQENAIIQEIVkYDREMVQQAELGQRVGLF-PPPPPPQVTSAIATLQQAVAMSFCPQVARPLVGPLALGsPrLVRRAPPGPLPPAAsPG-PPAAsPPAAPssPRAPRtsPy-GVPGsPATRVGPALPARRLSRASRPLSASQPSLPHGVPAPSPAASARPASSSTPRLGPAPTARTAAPsPDRRDsAsPGAAsGLDPLDSARSRLSsNL
HCN2 rat	MDARGGGGRPGDSPGATPAPGPPPPPPPPAPPQPQPPPAPP------PNPTTPSH--------PESADEPGPRSRLCSRDSSC----TPGA---AKGGANGECGRGEPQCS---PEGPARGPKVSFSCRGAASGPA----AAEEAGsEEAGPAGEPRGsQAsFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLF-PPPPPPQVTSAIATLQQAVAMSFCPQVARPLVGPLALGsPRLVRRAPPGPLPPAASPG-PPAAsPPAAPsSPRAPRTSPY-GVPGsPATRVGPALPARRLSRASRPLSASQPSLPHGAPAPSPAASARPAssSTPRLGPAPTTRTAAPSPDRRDSAsPGAASGLDPLDSARSRLSSNL
	***********:***:*****:***********:****:**......*:*::*:*........**:***:***:**:****:*....****...***::************...*********************:....:**********************:****************************************************************************************************************************************************************************************************************************************::******:**********************************************************************************************************************************************************************************************************************************************************************************:***********************************.******************:**************************:****:*:*****.**:****:**:**********.*:*::*::::**************************.:**:****:************:*::*:****************:****:***********
Consensus	MDARGGGGRPGDSPGATPAPGPPPPPPPPAPPQPQPPPAPP------PNPTTPSH--------PESADEPGPRARLCSRDSSC----TPGA---AKGGANGECGRGEPQCS---PEGPARGPKVSFSCRGAASGPA----AAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLF-PPPPPPQVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVRRAPPGPLPPAASPG-PPAASPPAAPSSPRAPRTSPY-GVPGSPATRVGPALPARRLSRASRPLSASQPSLPHGAPAPSPAASARPASSSTPRLGPAPTARTAAPSPDRRDSASPGAASGLDPLDSARSRLSSNL