Multiple Sequence Alignment:
FEN1 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410 )
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FEN1 human MGIQGLAkLIADVAPsAIrENDIkSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIkPVYVFDGkPPQLkSGELAkrsERrAEAEkQLQQAQAAGAEQEVEkFTkRLVkVTkQHNDECkHLLSLMGIPYLDAPSEAEASCAALVkAGkVYAAATEDMDCLTFGsPVLMrHLtAsEAkkLPIQEFHLSRILQELGLNQEQFVDLCILLGSDyCESIRGIGPKRAVDLIQkHksIEEIVRRLDPNkyPVPENWLHkEAHQLFLEPEVLDPEsVELkWSEPNEEELIkFMCGEkQFsEERIRSGVKRLsKsRQGstQGRLDDFFkVTGsLssAkRKEPEPKGstKKKAkTGAAGkFkRGk-------------------------------
FEN1 mouse MGIHGLAKLIADVAPSAIRENDIKsYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETT-SLMGMFYRTIRM-ENGIkPVYVFDGkPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAkKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGAKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLHKEAQQLFLEPEVVDPESVELKWSEPNEEELVKFMCGEKQFsEERIRSGVKRLSKSRQGsTQGRLDDFFKVTGSLSSAKRKEPEPKGPAKKKAKTGGAGKFRRGK-------------------------------
FEN1 iso2 mouse MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLHKEAQQLFLEPEVLDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGPAKKKAKTGGAGKFRRGKINLsFPSTVLDPRLSICFVPSAAAHPSCPSS
FEN1 rat MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYIFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGAEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAkKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESVRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLHKEARQLFLEPEVLDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLNKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGPAKKKAKTGGAGKFRRGK-------------------------------
  ***:*********************************************************::***********:********:*******************************:**:*:*********************************************:********************************************:*************************:****:**********************:*************.********:*****************:*********************:*********************************::*******:****:***                               
Consensus MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGAEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLHKEAQQLFLEPEVLDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGPAKKKAKTGGAGKFRRGK-------------------------------
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.