Multiple Sequence Alignment:
ASCC3 Download MSA
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ASCC3 human MALPRLTGALRsFSNVTkQDNYNEEVADLkIKRSKLHEQVLDLGLTWKKIIkFLNEkLEKSkMQSINEDLKDILHAAkQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIkQMFGPFPSSSATAACNATNRIISHFSQDDLTALVQMTEkEHGDrVFFGKNLAFsFDMHDLDHFDELPINGETQkTIsLDYkkFLNEHLQEACtPELkPVEKTNGsFLWCEVEKYLNStLkEMTEVPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSsNDHRFQALQDNCkkILGENAkPNYGCQVTIQSEQEkQLMkQYRREEKRIARREKkAGEDLEVS-EGLMCFDPkELRIQREQALLNARsVPILSRQRDADVEkIHYPHVYDSQAEAMkTSAFIAGAkMILPEGIQRENNkLYEEVRIPYSEPMPLsFEEkPVYIQDLDEIGQLAFkGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIkKNEFKIVYVAPMkALAAEMTDYFSRRLEPLGIIVKELtGDMQLSk
SEILRtQMLVTtPEkWDVVtRksVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVEsTQsMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANkMQQLNNMDEVCYENVLkQVKAGHQVMVFVHARNATVRTAMSLIERAkNCGHIPFFFPTQGHDYVLAEkQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAkRGSFVDLGILDVMQIFGRAGRPQFDkFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHkAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERtGyFSSTDLGRTASHYYIKYNTIETFNELFDAHkTEGDIFAIVSkAEEFDQIkVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPtMtyRLLNLSKVIDKRLWGWASPLRQFsILPPHILTRLEEKKLTVDkLKDMRkDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNkYPTSkAVYIAPLk
ALVRERMDDWKVRIEEk
LGKk
VIELTGDVTPDMkSIAkADLIVTTPEkWDGVSRSWQNRNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHtEkPVRIVGLstALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMAsMNkPAFQAIRsHsPAKPVLIFVsSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDsNLkLtLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGkTRRYVDFPITDVLQMMGRAGRPQFDDQGkAVILVHDIk
KDFYKkFLYEPFPVESSLLGVLSDHLNAEIAGGTItsKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYYLkHQTVkMFKDRLkPECSTEELLSILSDAEEYTDLPVRHNEDHMNSELAkCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDyDTDTKtVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFkKWKPIMkGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAkTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTADkRDDNkWIKLHADQEYVLQVSLQRVHFGFHKGkPESCAVTPRFPKSkDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDsLTDLALK
ASCC3 mouse MALPRLTGALRSFSNVTkQDNYNEEVADLkLKRSKLHEQVLDFGLTWKKIVKFLNEkLEkNkMQNINEDLKDILQAAKQIVGTDNGREAIESGAAFLFMTFHMTDSVGYMETKAIRQTFGPFPSSSATSACNATNRIISHFSQDDLTAFVQMAENPCNDRVVFGKNLAFSFDMYDLDHFDELPINGESQKTISLDYKKFLNEQFQEPYtPELkPVEkTNGSLLWCEVEKYLNATLkEMTEAARVEDLCCTLYDMLASAKSGDELQDELFELLGPEGLDLIEKLLQNRITIVDRFLNSSSDHKFQVLQDSCKKILGENSKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDGEVSGEGVLPFDPKELRIQREHALLNARNAPILGRQRDVEFEkIRYPHVYDSQAQARETSAFIAGAkMILPEGIQRENTKLYEEVRIPYGEPMPVGFEEkPVyIkDLDEVGQLAFkGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTILHEIRQHFHQGVIKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSkSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFYFDGRFRPVPLGQTFLGIKSTNKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQISCFLPTEGPEYGHALkQVQkSRNkQVRELFSDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVVIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEAVRWMSYTYLYVRMRANPLAYGISHkAYQIDPTLRKHREQLLIEVGQKLDKAKMIRFEERTGYFSSTDLGRTASHFYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEKNLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIHPDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLkALVRERMDDWKIRIEEKLGKkVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNkPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEQEMDNIIGTVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDAMDYITWTYFFRRLIMNPSYYSLGDVSQDSINKFLSHLIGQSLVELELSHCIEVGEDNRTIEPLTCGRIASYYYLKHKTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTVLNITHLIQMVIQGRWLKDSSLLTIPNIEQHHLHLFRKWKPPVKSSHAKCRTSIECLPELIHACEGKDHVFSSMVEKELQPAKTkQAWNFLSRLPVINVGISVKGSWDDLVEGHNELSISTLTADKRDENKWIKLHADQEYVLQVSLQRVHFGLPKGKHENHAVTPRFPKLKDEGWFLILGEVDKRELMAVKRVGFVRTHHDASISFFTPETPGRYIFTLYLMSDCYLGLDQQYDIYLNVIKANISTKDSDVFTDLsV-----
ASCC3 rat MALPRLTGALRSFSNVTKQDNYNEEVADLKLKRSKLHEQALDFGLSWKKIVKFLNEKLEKNKMQTINEDLKDILQAAKQIVGTDNGNEAIESGAAFLFMTFHMTDSVGYTETKAIRQMFGPFPSSSATSACNATSRIISHFSQDDLTALVQATENQCNDRVVFGRNLAFSFDMHDLDHFDELPVNGEAQKTISLDYKKFLNEQFQEPYTPELKPVEKSNGSLLWCEVEKYLNATLKEMTEAPRVEDLCCTLYDMLASAKSGDELQDELFELLGPGGLDLIEKLLQNRITIVDRFLNSSSDHKFQVLQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDGEVSGEGLLPFDPKELRLQREHALLNARSAPILGRQRDTEVEKIRYPHVYDSQAAARETSAFIAGAKMILPEGIQRENTKLYEEVRIPYSEPMPVGFEEKPVYIQDLDEVGQLAFKGMKRLNRIQSIVFDTAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFHQGVLKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSkSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLsAtLPNYLDVATFLHVNPYIGLFyFDGRFRPVPLGQTFLGIKSANKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQISCFLPTQGPEYGHALKQVQKSRNKQVRELFSDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEAVKWMSYTYLYVRMRANPLAYGISHKAYQMDPTLRKHREQLLIEVGQKLDKARMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEkNLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIYPDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPVTALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKIRIEEkLGkKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQESHTHCPDRPCLLLP-ERMLSSMTKLELIAFLATEEDPKQWLNMDEQEMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSQDAINKFLSHLIGQSLVELELSHCIEVGEDNRSIEPLTCGRIASYYYLKHKTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTTLNITHLIQMVIQGRWLKDSSLLTIPNIEQHHLHLFRKWKPPVKGPHAKCRTSIECLPELIHACEGKEHVFSSMVEKELQPAKTKQAWNFLSHLPVINVGISVKGSWDDSVEGHNELSISTLTADKRDENTWIKLHADQQYVLQVSLQRVHFEFHKVKHESHAVTPRFPKLKDEGWFLILGEVDKRELVAVKRVGFVRTHHEASISFFTPEAPGRYIFTLYLMSDCYLGLDQQYDIFLNVTKADISTQINTEVPDVST-----
  ******************************:********:**:**:****:*********:***.*********:***********:***************::****:.*****:*:**********:*****:*************:**::*:.::***:**:********:*********:***:**************::**::*********:***:**********:*******::***************:****************:**:********************:**:**:***:********:***************************************:***:**:::*******:***:******::***:****:::***:*********:*::********************:**********:****::********:****:*******************:**************************:********:***:*********************:***:*******:*********************************************:****************************************************************:******************::***************:**********************************:*:*::*:**:*::*::*:****:**********:***********************************************:*****************************************************:****:*******************************:*:************************:***********:****:*****.**********************:***********************************************:**:******:*************************************************************************************:************:*************************************:***************:*:*::**:***************************************:**************************************************************:***********************************************************************************:***********************************************:*****:***************************************************************************************************::::*:*::*:*:::::*:::::*:*********************:**:***:*****************************************************************************************************************************************************:*******************:*****:*::********::**:*****:***:*****:*****:***********:***************************************:*:*********:*****************************************************:******:****:******************:****:******:****::*::**::*****:********:**:********:**::***********:****************:********:*********:*:********:************:::*:*:*::********:*****************.*:****::*:**.**:**:***:*****:***:**************:***::*.:*::.::.:.*.::.....
Consensus MALPRLTGALRSFSNVTKQDNYNEEVADLKLKRSKLHEQVLDFGLTWKKIVKFLNEKLEKNKMQNINEDLKDILQAAKQIVGTDNGREAIESGAAFLFMTFHMTDSVGYKETKAIRQMFGPFPSSSATSACNATNRIISHFSQDDLTALVQMTENQCNDRVVFGKNLAFSFDMHDLDHFDELPINGEAQKTISLDYKKFLNEQFQEPYTPELKPVEKTNGSLLWCEVEKYLNATLKEMTEAPRVEDLCCTLYDMLASAKSGDELQDELFELLGPEGLDLIEKLLQNRITIVDRFLNSSSDHKFQVLQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDGEVSGEGLLPFDPKELRIQREHALLNARSAPILGRQRDAEVEKIRYPHVYDSQAAARETSAFIAGAKMILPEGIQRENTKLYEEVRIPYSEPMPVGFEEKPVYIQDLDEVGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFHQGVIKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFYFDGRFRPVPLGQTFLGIKSANKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQISCFLPTQGPEYGHALKQVQKSRNKQVRELFSDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEAVKWMSYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLLIEVGQKLDKARMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEKNLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIYPDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKIRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEQEMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSQDSINKFLSHLIGQSLVELELSHCIEVGEDNRSIEPLTCGRIASYYYLKHKTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTVLNITHLIQMVIQGRWLKDSSLLTIPNIEQHHLHLFRKWKPPVKGPHAKCRTSIECLPELIHACEGKDHVFSSMVEKELQPAKTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSISTLTADKRDENKWIKLHADQEYVLQVSLQRVHFGFHKGKHESHAVTPRFPKLKDEGWFLILGEVDKRELIAVKRVGFVRTHHDASISFFTPEAPGRYIFTLYLMSDCYLGLDQQYDIYLNVTKANISTQDNTEVPDLST-----
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.