Multiple Sequence Alignment:
HMGCL Download MSA
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HMGCL human MAAMRKALPRRLVGLAsLRAVstSSMGTLPKRVKIVEVGPRDGLQNEkNIVSTPVKIKLIDMLSEAGLSVIETTSFVsPkWVPQMGDHTEVLkGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFGAASELFTKkNINCSIEESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCyEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQATCkL
HMGCL iso2 human MAAMRKALPRRLVGLASLRAVSTSSMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGFEAA-----------------------------------------------------------------------VTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQATCKL
HMGCL mouse MASVRKAFPRRLVGLTSLRAVSTSSMGTLPKQVKIVEVGPRDGLQNEkSIVPTPVKIRLIDMLSEAGLPVIEATSFVSPkWVPQMADHSDVLkGIQkFPGINYPVLTPNMkGFEEAVAAGAKEVSVFGAVSELFTRkNANCSIEESFQRFAGVMQAAQAASISVRGYVSCALGCPYEGkVSPAKVAEVAkkLYSMGCYEISLGDTIGVGTPGLMKDMLTAVMHEVPVTALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDLVYMLNGLGIHTGVNLQKLLEAGDFICQALNRKTSSKVAQATCkL
HMGCL rat MATVRKAFPQRLVGLASLRAAStSSMGTLPKRVKIVEVGPRDGLQNEkSIVPTPVKIkLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNMkGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAVLHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDLVYMLTGLGIHTGVNLQKLLEAGDFICQALNRKTSSKVAQATCKL
  **::***:*:*****:****:**********:****************:**:*****:**********:***:************:**::*******************:****:*::::::::..:::.:::::.::.:::::::::::::...::..:.::::::::::::::::::.:::::::*:**:********************:*****:**::***::******************:**********************:***************.*****************:*********************
Consensus MAAMRKALPRRLVGLASLRAVSTSSMGTLPKRVKIVEVGPRDGLQNEKNIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADHSDVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVSIFGAASELFTRKNANCSIEESFQRFDGVMQAAQAASISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQATCKL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.