Multiple Sequence Alignment:
ACO2 Download MSA
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ACO2 human MAPYSLLVtRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEyIHYDLLEkNINIVRKRLNRPLTLSEKIVYGHLDDPAsQEIERGKsYLRLRPDRVAMQDATAQMAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAkDINQEVyNFLATAGAKYGVGFWKPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVkLTGsLSGWssPkDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSktGREDIANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGKVAEkEGWPLDIRVGLIGSCTNSSyEDMGRSAAVAkQALAHGLkCkSQFTITPGSEQIRATIERDGyAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNtIVtsYNrNFtGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDyLtGTDGkkFrLEAPDADELPkGEFDPGQDtyQHPPkDSSGQHVDVsPTSQRLQLLEPFDkWDGkDLEDLQILIKVKGKCTTDHISAAGPWLkFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDtARYYKKHGIRWVVIGDENyGEGssREHAALEPrHLGGRAIITkSFARIHETNLkkQGLLPLTFADPADYNKIHPVDkLTIQGLkDFTPGkPLKCIIkHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-
ACO2 mouse MAPYSLLVTRLQKALGVRQYHVASVLCQRAkVAMSHFEPSEYIRYDLLEkNINIVRKRLNRPLtLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFIssGLPKVAVPSTIHCDHLIEAQVGGEkDLRRAkDINQEVYNFLATAGAkYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELkCPkVIGVkLTGsLSGWTSPkDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMkkYLSKTGRTDIANLAEEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADVGTVAEkEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAkQALAHGLkCkSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRkDIkkGEkNTIVTSYNRNFtGRNDANPETHAFVTSPEIVtALAIAGTLKFNPETDFLTGkDGkkFkLEAPDADELPRsDFDPGQDTYQHPPkDSsGQRVDVsPtSQRLQLLEPFDkWDGkDLEDLQILIKVKGkCttDHISAAGPWLkFRGHLDNISNNLLIGAINIENGkANSVRNAVTQEFGPVPDTArYYkkHGIRWVVIGDENYGEGsSREHAALEPRHLGGRAIITkSFARIHETNLkkQGLLPLTFADPsDYNKIHPVDkLTIQGLkDFAPGkPLkCVIkHPnGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-
ACO2 rat MAPYSLLVTRLQKALGVRQYHVASALCQRAKVAMSHFEPSEYIRYDLLEkNINIVRKRLNRPLTLSEkIVyGHLDDPANQEIERGkTyLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEkDLRRAkDINQEVyNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPkVIGVkLTGTLSGWTSPkDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMkkYLSkTGRADIANLAEEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAkQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKkGEKNTIVtSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGkDGkkFkLEAPDADELPRSDFDPGQDTyQHPPkDSSGQRVDVsPtSQRLQLLEPFDkWDGkDLEDLQILIKVKGKCTTDHISAAGPWLkFRGHLDNISNNLLIGAINIENGkANSVRNAVTQEFGPVPDTARYYKkHGIRWVVIGDENyGEGsSREHAALEPRHLGGRAIITkSFARIHETNLkKQGLLPLTFADPSDYNkIHPVDkLTIQGLkDFAPGKPLNCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-
ACO2 pig MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPHEYIRYDLLEKNIDIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQVLRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIGDENYGEGSSREHRALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQK
ACO2 cow MAPYSLLVSRLQKALGARQYHVASVLCQRAKVAMSHFEPNEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDSGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLQCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQQVDVSPTSQRLQLLEPFDKWDGRDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINVENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIKGLKDFAPGKPLTCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQK-
  ********:*******:*******:**************.***:********:*************************:*******:****************************:*****************:********************************:*********************************************************************:****:**********************************************************************:******:*********:**:***:*****:*******************:**.******************************************:*************************:***:*************************************************************************:***:*****:**********:::******************:*********************:**********************************************:**:************************:*********************:**************************************:*************:*****:*****:*:**************************************: 
Consensus MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLADEFKDHLVPDPGCHYDQVIEINLSELKPHINGPFTPDLAHPVAEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ-
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.