Multiple Sequence Alignment:
FECH Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420   )
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FECH human MRSLGANMAAALRAAGVLLRDPLASSSWRVCQPWRWkSGAAAAAVTTEtAQHAQGAkPQVQPQKRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNkLAPFIAKRRTPKIQEQYRRIGGGSPIKIWTSKQGEGMVKLLDELsPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYyNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSkVGPMPWLGPQtDEsIkGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETkSFFTsQQL
FECH iso2 human
FECH mouse MLSASANMAAALRAAGALLREPLVHGSSRACQPWRCQSGAAVAA-TTEKVHHAKTTKPQAQPERRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLPIQNkLAPFIAKRRTPKIQE--RRIGGGSPiKMWTSKQg
EGMVKLlDELSPATAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGQKPt
MKWsTIDRWPTHPLLIQCFADHILKELNHFPEEKRsEVVILFSAHSLPMSVVNRGDPYPQEVGATVHKVm
EKLg
YPNPYRLVWQSKvgPVPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQKCGAENIRRAESLNGNPLFSKAlADLVHSHIQSNKLCSTQLSLNCPLCVNPVCRKTKSfFTSQQL
FECH rat
FECH cow -------MAAALRSAGVLLRDRLLYGGSRACQPRRCQSGAATAAAATETAQRARsPKPQAQPGNRKPRTGILMLNMGGPETVEEVQDFLQRLFLDQDLMTLPVQDKLGPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPHTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAVAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPPEKRREVVILFSAHSLPMSVVNRGDPYPQEVGATVQRVMDKLGYSNPYRLVWQSKVGPMPWLGPQTDEAIKGLCKRGRKNILLVPIAFTSDHIETLYELDIEYSQVLASECGLENIRRAESLNGNPLFSKALADLVHSHLQSKERCSTQLTLSCPLCVNPTCRETKSFFTSQQL
  :.:..::******:**:***::*:.:::*:***:*::****:**.:**::::*..:***:**..***:*************:::*:***:*****:******:*:**:*************::**********:******************:********************************:*************************:**:***************:**************:***.***:**************************:***::**::*:*.*************:*********:*****:*********************************.:**:**************************:**:::**:**:*:*******:**:**********
Consensus MRSAGANMAAALRAAGVLLRDPLAHGSSRACQPWRCQSGAAAAAATTETAQHARGAKPQAQPQRRKPKTGILMLNMGGPETLGEVQDFLQRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIGGGSPIKMWTSKQGEGMVKLLDELSPATAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIAFTQYPQYSCSTTGSSLNAIYRYYNEVGRKPTMKWSTIDRWPTHPLLIQCFADHILKELDHFPEEKRSEVVILFSAHSLPMSVVNRGDPYPQEVGATVQKVMEKLGYCNPYRLVWQSKVGPMPWLGPQTDEAIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAQECGAENIRRAESLNGNPLFSKALADLVHSHIQSNELCSTQLTLSCPLCVNPVCRETKSFFTSQQL
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.