Multiple Sequence Alignment:
TPM4 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290)
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TPM4 human MAGLNsLEAVkRkIQA-----------------------------------LQQQA-------DEAEDrAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLAtALQkLEEAEkAADEsERGMkVIENRAMKDEEKMEIQEMQLKEAkHIAEEADrkyEEVARkLVILEGELERAEERAEVSELKCGDLEEELkNVtNNLksLEAASEkYsEKEDkyEEEIkLLSDKLKEAEtRAEFAERTVAkLEktIDDLEEKLAQAkEENVGLHQtLDQtLNELNCI
TPM4 iso2 human ------MEAIKKKMQMLKLDKENAIDRAEQAEADKkAAEDKCkQVEEELTHLQKKLKGTEDELDKYsEDLKDAQEKLELTEKKAsDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAkEENVGLHQTLDQTLNELNCI
TPM4 mouse MAGLNsLEAVkRKIQA-----------------------------------LQQQA-------DDAEDRAQGLQRELDGERERREKAEGDAAALNRRIQLLEEELDRAQEQLATALQNLEEAEkAADESERGMkVIENRAMKDEEKMEILEMQLkEAkHITDEADRkyEEVARkLVILEGELKRAEERAEVSELKCGDLEEELKNVTNNLksLEAASEkYSEKEDkYEEEIKLLSDKLkEAETRAEFAERTVsKLEKTIDDLEEKLAQAkEENVGLHQTLDQTLNELNCI
TPM4 rat MAGLNsLEAVkRKIQA-----------------------------------LQQQA-------DDAEDRAQGLQRELDGERERREkAEGDAAALNRRIQLVEEELDRAQERLAtALQkLEEAEkAADESERGMkVIENRAMkDEEKMEIQEMQLKEAkHIAEEADRkYEEVARkLVILEGELERAEERAEVSELkSSDLEEELkNVTNNLkSLEAASEkYSEkEDkYEEEIKLLSDkLkEAEtRAEFAERTVSkLEkTIDDLEEkLAQAKEENVGLHQTLDQTLNELNCI
  :::::::**:*:*:*:                                   **:::       *.::::::::*::*:::::::::****:*********:*********:******:*******************************:**********::********************:************::*******************************************************:*************************************
Consensus MAGLNSLEAVKRKIQA-----------------------------------LQQQA-------DDAEDRAQGLQRELDGERERREKAEGDAAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQTLNELNCI
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.