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FAM83H human	MARRsQsssQGDNPLAPGyLPPHyKEYYRLAVDALAEGGsEAYSRFLATEGAPDFLCPEELEHVSRHLRPPQYVTREPPEGSLLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYILLDEMNAQHFLDMADKCRVNLQHVDFLRVRTVAGPTYYCRTGKSFKGHVKEKFLLVDCAVVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAAALARMDAyALAPYAGAGPLVGVPGVGAPTPFSFPkRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREEPPrMPGGALEPHAGLRPLsRRLEAEAGPAGELAGArGFFQARHLEMDAFk K408-m1 K408-ub RHsFAt-EGAGAVENFAAARQVSRQTFLsHGDDFrFQTSHFHRDQLyQQQyQWDPQLtPARPQGLFEkLrGGrAGFADPDDFTLGAGPrFPELGPDGHQRLDyVPssAsREVRHGsDPAFAPGPrGLEPSGAPrPNLtQrFPCQAAARPGPDPAPEAEPERRGGPEGRAGLRRWRLAsYLsGCHGEDGGDDGLPAPMEAEAYEDDVLAPGGRAPAGDLLPsAFRVPAAFPTkVPVPGPGsGG-NGPEREGPEEPGLAkQDsFRSRLNPLVQRSSRLRsSLIFSTsQAEGAAGAAAAtEKVQLLHKEQtVsEtLGPGGEAVRSAASTkVAELLEKYKGPARDPGGGAGAItVAsHsKAVVSQAWREEVAAPGAVGGERRsLESCLLDLRDSFAQQLHQEAERQPGAAsLTAAQLLDtLGRSGsDRLPSRFLSAQSHsTsPQGLDsPLPLEGSGAHQVLHN--------------------------------------------ESKGsPtsAyPERKGsPtPGFstRRGsPttGFIEQKGsPtsAyPERRGsPVPPVPERRssPVPPVPERRGsLtLTISGEsPKAGPAEEGPsGPMEVLRKGSLRLRQLLsPKGERRMEDEGGFPVPQENGQPEsPRRLsLGQGDstEAAtEERGPRARLssAtANALySSNLRDDtkAILEQIsAHGQkHRAVPAPsPGPtHNsPELGRPPAAGVLAPDMSDKDKCSAIFRSDsLGtQGRLSRtLPAsAEERDRLLRRMEsMRKEKRVySRFEVFCKKEEAssPGAGEGPAEEGtRDSKVGKFVPKILGTFkSkK
FAM83H mouse	MARRsQsssQGDNPLAPGYLPPHYKEYYRLAVDALTEGGPEAYNRFLASEGAPDFLCPEELEHVSRHLQPPQYVAREPPEGTPSDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHLKEKFLLVDCAVVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAGALARMDAYALAPYSGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREELQRMPGGALEPHTGLRPLARP--TEAGPFGELAGPRGFFQSRHLEMDAFKRHSYATPDGAGAVENFAAARQVSRQTFLsHGDDFRFQTsHFQRDQLYQQHYQWDPQFAPARPQGLFEKLRAGRPGFADPDDFALGAGHRFPELGADVHQRLEYVPssAsREVRHGsDPAFGPSPRGLEPsGASRPNLGQRFPCQATLRQGLDTASEAEPERRGGPEGRAGLRHWRLASYLSGCHGDGG-EEGL--PMEAEACEDEVLAPGGR----DLLPSAFRTPAAFPAKGPKPGsGsGGGDsSEREGPEETSLAKQDSFRSRLNPLIQRSSRLRSSLIFASQAEGAVGTAAATTEKVQLMHKEQTVSETLGPSGEAVRSSASAKVAELLEKYKGPARDPGGAGGAVTSSSHSKAVVSQAWREEVVAPGGAGTERRsLEsCLLDLRDSFAQQLHQEAERHPGAASLTAAQLLDTLG--GTDRLPSRFLSAQGRsLsPQGRDsPPP-EGLGtHQLPYSEPKGNPTPAYPERKGsPtPAyPERKGsPtPAYPERKGsPtPAyPERKGsPtQAYPERKGsPtSGFPNRRGsPttGLMEQKGsPtSTYPDRRGsPVPPVPERRGsPVPPVPERRGsLt--FAGESSKTGPTEEVSSGPMEVLRKGSLRLRQLLsPKNERRGEDEGSFPTPQENGQPESPRRPsLSRGDstEAAAEERGSRVRLASAtANALYSSNLRDDtKAILEQIsAHGQKHRGVPA--PGPAHSSPDVGRPTTAGDLAPDMSDKDKCSAIFRSDsLGTQGRLSRtLPGSAEERDRLLRRMEsMRKEKRVYSRFEVFCKKDEAGSSGAGDNLADEDtRDSKMGKFVPKILGTFKSKK
FAM83H rat	MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALTEGGQEAYNRFLASEGAPDFLCPEELEHVSRHLQPPQYVSREPPEGAPPDVDMDGSSGTYWPVDSDQAVPELDLGWPLTFGFQGTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHLKEKFLLVDCAVVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAGALARMDAYALTPYSGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRRDELQRMPGGALEPHTGLRPLARP--GEAGPLGELPGPRGFFQSRHLEMDAFKRHSYTAADGAGAVENFAAARQVSRQTFLSHGDDFRFQTSHFQRDQLYQQHYQWDPQFAPARPQGLFEKLRAGRPGFADPDDFALGAGHRFPELGADVHQRLEYVPsSASREVRHGsDPAFGPSPRGLEPSGASRPNLGQRFPCQATLRQGLDTATEAEPERRGGPEGRAGLRHWRLASYLSGCHGDGG-EEGL--PMEAEACEDEVLAPGGR----DLLPSTFRTPAPFPAKGPKPGSGSGGGDSSEREGPEETGLIKQDsFRSRLNPLIQRSSRLRSSLIFASQAEGTAGTTAATTEKVQLMHKEQTISETLGPSGEAVRSSASAKVAELLEKYKGPARDPGGAGGAITASSHSKAVVSQAWREEVVAPGGAGAERRSLESCLLDLRDSFAQQLHQEAERHPGAASLTAAQLLDTLG--GTDRLPSRFLSAQGRSLsPQGRDsPPP-EGLGTHQLPYSEPKGsPTPAYPERKGsPTPAYPERKGsPTPAYPERKGsPTPAYPERKGsPTPAYPERKGsPTSGFPNRRGsPTTGLMEQKGSPTSTYPDRRSSPVPPVPERRGsPVPPVPERRGsLT--FAGESSKTGPTEEVSGGPMEVLRKGSLRLRQLLsPKSERRGEDEVSFPAPQENGQPESPRRPsLSRGDsTEAAAEERGSRVRLASATANALYSSNLRDDTKAILEQISAHGQKHRAVPA--PGPAHNSSDVGRPTTAGDLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMRKEKRVYSRFEVFCKKEDAGSSAAGDNLADEDTRDSKMGKFVPKILGTFKSKK
	***********************************:***.***:****:*******************:*****:******::.**************:*****************************************************************************************************:**************************:************************************************************:**********:**:*****************************************************:*::**********:*****:*:..:****:***:*:*****:************:::.:*********************************:*******:******::************:**:********:****:******:*:****:******************:*:*********:****:*******::*:*:*:*.*****************:************::*.::**..******:**:*******....*****:**:**:**:*:*:**:****::::*******::*:************:************:::::::::::**:******:*****:******:******:**:******************::**:*::***************:***::*:**************************:****************..*:***********::*:****:***:*.**:*:**::::::::.:::::::::::::::::::::::::::::::::::::::*:*****.**********:**::********::********:**:**:**********:**************..::***:*:**:**:::********************.***:***::**:************:**::*******:****:*:**:*******************************:***..***:*:*:::***::**:*******************************:*******************************::*:*::**:::*:*:*****:***************
Consensus	MARRSQSSSQGDNPLAPGYLPPHYKEYYRLAVDALTEGGQEAYNRFLASEGAPDFLCPEELEHVSRHLQPPQYVAREPPEGAPLDVDMDGSSGTYWPVNSDQAVPELDLGWPLTFGFQGTEVTTLVQPPPPDSPSIKDEARRMIRSAQQVVAVVMDMFTDVDLLSEVLEAAARRVPVYILLDEMNAQHFLDMADKCRVNLHHVDFLRVRTVAGPTYYCRTGKSFKGHLKEKFLLVDCAVVMSGSYSFMWSFEKIHRSLAHVFQGELVSSFDEEFRILFAQSEPLVPSAGALARMDAYALAPYSGAGPLVGVPGVGAPTPFSFPKRAHLLFPPPREEGLGFPSFLDPDRHFLSAFRREELQRMPGGALEPHTGLRPLARP--AEAGPAGELAGPRGFFQSRHLEMDAFKRHSYATADGAGAVENFAAARQVSRQTFLSHGDDFRFQTSHFQRDQLYQQHYQWDPQFAPARPQGLFEKLRAGRPGFADPDDFALGAGHRFPELGADVHQRLEYVPSSASREVRHGSDPAFGPSPRGLEPSGASRPNLGQRFPCQATLRQGLDTAPEAEPERRGGPEGRAGLRHWRLASYLSGCHGDGG-EEGL--PMEAEACEDEVLAPGGR----DLLPSAFRTPAAFPAKGPKPGSGSGGGDSSEREGPEETGLAKQDSFRSRLNPLIQRSSRLRSSLIFASQAEGAAGTAAATTEKVQLMHKEQTVSETLGPSGEAVRSSASAKVAELLEKYKGPARDPGGAGGAITASSHSKAVVSQAWREEVVAPGGAGAERRSLESCLLDLRDSFAQQLHQEAERHPGAASLTAAQLLDTLG--GTDRLPSRFLSAQGRSLSPQGRDSPPP-EGLGTHQLPYSEPKGNPTPAYPERKGSPTPAYPERKGSPTPAYPERKGSPTPAYPERKGSPTQAYPERKGSPTSGFPNRRGSPTTGLMEQKGSPTSTYPDRRGSPVPPVPERRGSPVPPVPERRGSLT--FAGESSKTGPTEEVSSGPMEVLRKGSLRLRQLLSPKNERRGEDEGSFPAPQENGQPESPRRPSLSRGDSTEAAAEERGSRVRLASATANALYSSNLRDDTKAILEQISAHGQKHRAVPA--PGPAHNSPDVGRPTTAGDLAPDMSDKDKCSAIFRSDSLGTQGRLSRTLPASAEERDRLLRRMESMRKEKRVYSRFEVFCKKEEAGSSGAGDNLADEDTRDSKMGKFVPKILGTFKSKK