Multiple Sequence Alignment:
PAICS	Download MSA

	( 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 )
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PAICS human	MAtAEVLNIGk K11-ub K11-sc kLyEGKt kEVyELLDsPGk K30-ac K30-ub VLLQsk K36-ub K36-sc DQItAGNAARkNHLEGk K53-ac K53-ub AAISNKITSCIFQLLQEA-------GIkTAFTRkCGETAFIAPQCEMIPIEWVCRRIAtGsFLk K110-ac K110-ub K110-sc RNPGVk K116-ub K116-sc EGYkFyPPkVELFFkDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKsWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDsWRLWPSGDr sQQKDkQs yRDLkEVtPEGLQMVk K246-ac K246-ub k K247-ac K247-ub NFEWVAERVELLLk K261-ac K261-ub SESQCRVVVLMGsTsDLGHCEk K283-ac K283-ub IKkACGNFGIPCELRVTSAHk K304-ac K304-ub GPDEtLrIk K313-ub K313-sm AEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAyPVISCPPLtPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLsNHLVWsKLRAsILNTWIsLkQADKKIRECNL
PAICS iso2 human	MATAEVLNIGKKLYEGKTKEVYELLDSPGKVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEAVTSYKSNRIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASILNTWISLKQADKKIRECNL
PAICS mouse	MATAVVVNIGKKLYEGKTKEVyELLDtPGRVLLQSkDQITAGNAARKNHLEGkAAISNKITSCIFQLLQEA-------GIKTAFTKKCGETAFIAPQCEMIPIEWVCRRIATGsFLkRNPGVQEGYk K120-ac K120-ub FYPPKVEMFFKDDANNDPQWSEEQLIAAKFCFAGLVIGQTEVDIMSHATQAIFEILEKSWLPQDCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQsYRDLkEVtPEGLQMVKKNFEWVADRVELLLKSDSQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVSVAGRSNGLGPVLSGNTAYPVISCPPITPDWGAQDVWSSLRLPSGIGCSTILSPEGSAQFAAQIFGLNNHLVWAKLRASILNTWISLKQADKKVRQCNL
PAICS rat	MATAEVLNIGRKLYEGKTKEVYELLDsPGRVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEA-------GIKTAFTKKCGETAFIAPQCEMIPIEWVCRRIATGsFLkRNPGVKEGYRFYPPKVEMFFKDDANNDPQWSEEQLIAAKFCFAGLVIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVADRVELLLKSNSQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPITADWGAQDVWSSLRLPSGIGCSTILSPEGSAQFAAQIFGLNNHLVWAKLRASKLNTWISLKQADKKIRECNL
	***::*:***********::*************************************** :**:********************************::****:***********************:***********************:*****************************************************************:****.***********************************************************:*******:**********::*:********::************:*:*:**********::***
Consensus	MATAEVLNIGKKLYEGKTKEVYELLDSPGRVLLQSKDQITAGNAARKNHLEGKAAISNKITSCIFQLLQEA-------GIKTAFTRKCGETAFIAPQCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLLIGQTEVDIMSHATQAIFEILEKSWLPQNCTLVDMKIEFGVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVADRVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPITPDWGAQDVWSSLRLPSGIGCSTILSPEGSAQFAAQIFGLNNHLVWAKLRASILNTWISLKQADKKIRECNL

Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.

Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.