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EHHADH human	MAEYTRLHNALALIRLRNPPVNAISttLLRDIKEGLQKAVIDHTIKAIVICGAEGkFSAGADIRGFSAPRTFGLTLGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLItSGRRILADEALkLGILDkVVNSDPVEEAIRFAQRVsDQPLEsRRLCNKPIQSLPNMDSIFSEALLkMRRQHPGCLAQEACVRAVQAAVQyPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANkWsTPSGASWKTASARPVSsVGVVGLGtMGRGIVISFARARIPVIAVDSDkNQLATANKMITsVLEkEASKMQQSGHPWsGPKPRLTsSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSkKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWkSRKGQGLTGPTLLPGtPARKRGNRRYCPIPDVLCELGRFGQKTGkGWyQyDkPLGRIHKPDPWLSkFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFyASTVGLPTVLEKLQKyyRQNPDIPQLEPSDYLKKLAsQGNPPLKEWQsLAGsPSSkL
EHHADH iso2 human	------------------------------------------------------------------------------------------------MAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVVGLGTMGRGIVISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPKPRLTSSVKELGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTDRPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNRMLNPYYNQAYFLLEEGSKPEEVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPTLLPGTPARKRGNRRYCPIPDVLCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRHKGGPMFYASTVGLPTVLEKLQKYYRQNPDIPQLEPSDYLKKLASQGNPPLKEWQSLAGSPSSKL
EHHADH mouse	MAEyLRLPHSLAMIRLCNPPVNAIsPtVITEVRNGLQk K38-ub K38-sc ASLDHTVRAIVICGANDNFCAGADIHGFKS--PtGLTLGsLVDEIQRYQKPVVAAIQGVALGGGLELALGCHYRIANAk K115-ac K115-sc ARVGFPEVMLGILPGARGTQLLPRVVGVPVALDLITSGRHISTDEALk K163-ac K163-ub K163-sc LGILDVVVk K172-ac K172-ub K172-sc SDPVEEAIkFAQTVIGk K189-ac K189-ub K189-sc PIEPRRILNKPVPSLPNMDSVFAEAIAk K217-ac K217-sc VRKQYPGRLAPETCVRSVQASVk K240-ac K240-sc HPYEVAIk K248-ac K248-ub K248-sc EEAk K252-ac K252-sc LFMYLRGSGQARALQYAFFAEk K274-ac K274-ub K274-sc SANk K278-ac K278-ub K278-sc WSTPsGAsWkTAsAQPVssVGVLGLGtMGRGIAISFARVGIPVVAVESDPk K329-ac K329-ub K329-sc QLDTAk K335-ac K335-sc k K336-ac K336-ub K336-sc IITstLEk K344-ac K344-ub K344-sc EASk K348-ac K348-ub ---SGQASAk K355-ac K355-sc PNLRFSSSTKELSSVDLVIEAVFEDMNLKKkVFAELSALCKPGAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHIMRLLEVIPSRYSSPtTIAtVMSLSk K459-ac K459-ub K459-sc RIGkIGVVVGNCYGFVGNRMLAPYYNQGYFLIEEGSKPEDVDGVLEEFGFRMGPFRVSDLAGLDVGWk K527-ac K527-ub K527-sc VRkGQGLtGPsLPPGtPTRKRGNTRYSPIADMLCEAGRFGQkTGk K572-ac K572-ub K572-sc GWYQYDk K579-ac K579-ub K579-sc PLGRIHk K586-ac K586-sc PDPWLSEFLSQYRETHHIkQRsIskEEILERCLYSLINEAFRILEEGMAASPEHIDVIYLHGYGWPRHVGGPMYYAASVGLPTVLEkLQKYYRQNPDIPQLEPSDYLRRLVAQGsPPLkEWQsLAGPHssk K717-ac K717-sc L
EHHADH rat	MAEYLRLPHSLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAF-TPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGkYLSADEALRLGILDAVVkSDPVEEAIkFAQkIIDkPIEPRRIFNKPVPSLPNMDSVFAEAIAkVRKQYPGVLAPETCVRSIQASVkHPYEVGIkEEEKLFMYLRASGQAkALQYAFFAEkSANkWSTPSGASWKTASAQPVSSVGVLGLGtMGRGIAISFARVGISVVAVESDPkQLDAAKkIITFTLEkEASRAHQNGQASAKPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWkIRKGQGLTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQyDkPLGRIHkPDPWLSTFLSQYREVHHIEQRTISkEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQkYYRQNPDIPQLEPSDYLRRLVAQGSPPLkEWQSLAGPHGSkL
	::::.::..:::.:::.::::::.:.:.......:::::..:::..:::::::...:.:::::.::... ..:::::..::::::..:::.::::::*:***************:*:*:**:***:**:************::***:********:.:::****:*****:**:********:***.::::*:*:**:.***::*******:*:**::*:*:*:**.**:*:***::**:*::****:**:*::**:**::****:*********::*****************:*******:*********:*****::*:*:**:**::**::*:*:**::******::.::*:::::*::*::**:***:.****:*****:*:***:*******:***:**********:**:********:************:*:*******:***********:***:*:*********:********:*****::**:*******:**:*******:*****************.*********:*:****:*****.**:*::*:***:*****************************.***:**::***::*:**::******************:**:**:******:**********:****:**::*****************************::*::**:***********:::***
Consensus	MAEYLRLPHSLAMIRLCNPPVNAISPTVIREVRNGLQKAGIDHTVKAIVICGANGNFCAGADIHGFSA--TFGLTLGSLVDEIQRYQKPVVAAIQGMALGGGLELALGCHYRIANAEARVGLPEVTLGILPGARGTQLLPRLTGVPAALDLITSGRRILADEALKLGILDKVVNSDPVEEAIRFAQRVIDQPIEPRRICNKPIQSLPNMDSIFAEAIAKMRRQHPGCLAQEACVRAVQAAVQHPYEVGIKEEEELFLYLRQSGQARALQYAFFAERKANKWSTPSGASWKTASARPVSSVGVLGLGTMGRGIAISFARARIPVIAVDSDKNQLATANKIITSTLEKEASKMQQSGQASAGPKLRLSSSTKELGGVDLVIEAVFEDMNLKKQVFAELSALCKPEAFLCTNTSALDVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMNLSKKIGKIGVVVGNCFGFVGNRMLAPYYNQAYFLLEEGSKPEDVDQVLEEFGFKMGPFRVSDLAGLDVGWKSRKGQGLTGPSLLPGTPARKRGNRRYCPIPDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKFLSRYRETHHIEQRTISQDEILERCLYSLINEAFRILEEGIAASPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDIPQLEPSDYLRRLAAQGNPPLKEWQSLAGPHSSKL