(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260         )
	|         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |
APOOL human	MAAIRMGKLTTMPAGLIYASVSVHAAKQEESKkQLVKPEQ-LPIytAPPLQSKYVEEQPGHLQMGFASIRTATGCYIGWCKGVYVFVKNGIMDTVQFGKDAyVYLKNPPRDFLPKMGVITVSGLAGLVSARKGSKFKKITYPLGLATLGATVCYPVQSVIIAKVTAKKVYATSQQIFGAVKSLWTKSSKEESLPKPKEKTKLGsssEIEVPAKTTHVLKHsVPLPTELSSEAKtKSEStSGATQFMPDPKLMDHGQsHPEDIDMYSTRS
APOOL mouse	MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLVRPDQ-LPIYTAPPLHsKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVIIAKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRsDEIHAs---LPDLKHsVsLPKELASATVIKSEsTsGTTQFIPDPKLMDHGQsHPDDKDMYSTRS
APOOL iso2 mouse	MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLsETRISsLLYTAPPLHSKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVIIAKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRSDEIHAS---LPDLKHSVSLPKELASATVIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS
	***:*******:********::*::**:**:****:.:.:.:::******:*********:**:*******:*::******::*:*:***:******************:**********:******:******:****:***************:*******:*:**:********:*:*****::*::****:***::*:*:*:**:::...:::*****:**:**:*::::*******:***:*************:*:*******
Consensus	MAAFRMGKLTTIPAGLIYASINVRLAKEEEPKKQLVRPRQ-LPIYTAPPLHSKYVEEQPGNLQRGFASIRTTTVYYIGWCKSIYLFMKNGVMDTVQFGKDAYVYLKNPPQDFLPKMGVITASGLAGLLSARKGSRFKKIAYPLGLATLGATVCYPAQSVIIAKITGKKAYATSQQIFQAIKSLWTQKSENESLPEPKEESKEGRSDEIHAS---LPDLKHSVSLPKELASATVIKSESTSGTTQFIPDPKLMDHGQSHPDDKDMYSTRS