Multiple Sequence Alignment:
HRC1 Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370         )
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HRC1 human MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSsDSCPPPERCLIRASLPVkPRAALGCEPrKTLt-----PEPAPSLSRPGPAAPVtPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPsPMASAtERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPR-PDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPAPEWCPLAAQPQAL
HRC1 iso2 human MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLT-----PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPR-PDRGPPGTQVGVVLGGGWEVRTWP-------SPTPS-----------------------------
HRC1 iso3 human MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLT-----PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPR-PDRGPPGTQWPP-----------------------------------------------------
HRC1 mouse MVLELVAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFANDVQFVLRRTGPSLSGRPSSDNCPPPERCPVRASLPPKPSAIPGREPRKALTFNLRCPKLVPSPSIPEPAALVGPIPDGFADLQDLELRIQRNTEELGHEAFWEQELQREQAREREGQARLQALSAATAEHAARLEALDAQACALEAELRLAAEAPGPPSATASAAERLRQDLATQERHSLEMQGTLALVSQALEAAEHALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPPQLDRTIPSTQDLLSPNRGE-LQGVPQSHILVSSLSPE----------VPPMRQSSWR---------
  *:*:*:***********************************************************************:*************:******:*******::*****:**:*::*:****:**     *:::**:*:*:***:*:*:*::::**::****:***:*************:***************************:******:******:**********::***:***:****:***:*:*:**:*****:******:************************************: :**::*:**..............:..........:.          ..........         
Consensus MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQFASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLT-----PEPAPSLSRPGPAAPVTPTPGCCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAAEAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTGAALPPPPR-PDRGPPGTQDPLPPARGE-LRGAP-------SPRPR----------V-------W----------
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.