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USP16 human	MGKKRTKGktVPIDDSSETLEPVCRHIRk K29-ac K29-ub GLEQGNLk K37-ac K37-ub KALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNsPCQITVKGLsNLGNTCFFNAVMQNLSQTPVLRELLKEVKMsGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFkGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNsTEkLDEELKNKVKDYEKKKSMPsFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLsLPVLDDQSGKKSVNDKNLKKTVEDEDQDsEEEKDNDsYIkERSDIPSGTSkHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEYEAEMsLQGEVN--IKSNHISQEGVMHkEyCVNQkDLNGQAkMIEsVTDNQKsTEEVDMKNINMDNDLEVLtssP--TRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDsHtPGTKVyEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVLysLYGVVEHSGTMRSGHYTAYAkARTANSHLSNLVLHGDIPQDFEMES-KGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL
USP16 mouse	MGKKRTKGRSAPDTVAsESAEPVCRHLRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKPEEE-AEDPSVWLCLKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEVKYCSSNRLGQVVDYVRKQAGVRTSKPAEKNNGHIELENKKLEKESKNEQEREKSENLAKETIPMDSASQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEVNLEPPGPLTLAMSQFLSEMQENKKRVVTPkELFSQVCKKATRFkGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEEVKNKVKDYEKKKAIPSFVDRIFGGELTSTIMCDECRTVSLVHESFLDLSLPVLDDQSGKKSINDKNVKMTMEEEDKDsEEEK-DDSYMKSRSDLPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQERFLHFNELCATDYTEDNEREADTALAGEVEVDTDSTHGSQEEATQIELSVNQKDLDGQEsMIERTPDVQEsPEDLGVKSANTESDLGIVTPAPECPRDFNGAFLEERTsGELDIINGLKNLNLNAAVDPDEINIEIPNDSHS-APKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEKLQDANKLLCEVCSRRQCNGPKANIKGDRRHVYTNAKkQMLVSLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEESTRVLysLYGVVEHSGTMRSGHYTAYAKERTASCHLSNLVLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYERIL
USP16 rat	MGKKRTKGKSVPEKASSESTEPMCRHLRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKSEEE-AEDPSVWLCLKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEIKYCSSNRLGQVVDYVRKQAGRITSKPAEKNNGHIELENKKLEKESKNEQEREKSESMAKENIPLDSASQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEVNLEPPGPLTLAMSQFLNEMQENKKRIVTPKELFSQVCKKATRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEEVKNKVKDYEKKKAIPSFVDRIFGGELTSTIMCDDCRTVSLVHESFLDLSLPVLDDQSGKKNINDKNVKKTMEEEDKDsEEEK-DDSYMKTRSDVPSGTSKHTQKKAKKQAKKQAKNQRRQQKIQERFLHFNEICTTNYTEDNDHEAETALPGEGEVDTEFNRGSQEELTQTELCANQKDVNGQEEMIESAADERKCPEHPEVKSVSTESDLGSLTSAPECPRDLNGAFLEERTSGELDITNGLKNLTLNAAVDPDEISIEILNDSHSPALKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEKLQDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLVSLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEESTRVLYSLYGVVEHSGTMRSGHYTAYAKERTASCHLSNLVLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYERIL
	********:::*..::**::**:***:*********************************:***.:*:****************:**********:*******:*************:**:*::*****:************:..*:*****:**:********************:*::***::*::*::*********************************************************:****************:****:**::**************:***********************************************:***********::**************:****.**************************::****:*:*:*:**:******.:***:*.***.*******:**********************:::**:*::*:::::**::.**:::*:**:::::.::::***::::.*:::****::**:.***:::*.::::*...:*::::::**:.:*::*:::*::***:*:*:::**:**.**:***:****::****:***:****:::.*****:***************:*:*******************:**********:*************:*:***********:**************************************************:***************************:***::**************:****:****************:*****************
Consensus	MGKKRTKGKSVPDDASSESAEPVCRHLRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEE-AEDPSVWLCLKCGHQGCGRDSQEQHALKHYTTPRSEPHYLVLSLDNWSVWCYKCDEEVKYCSSNRLGQVVDYVRKQAGRRTSKPAEKNNGHIELENKKLEKESKNEQEREKSENMAKENIPMDSASQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEVNLEPPGPLTLAMSQFLNEMQENKKRVVTPKELFSQVCKKATRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEEVKNKVKDYEKKKAIPSFVDRIFGGELTSTIMCDDCRTVSLVHESFLDLSLPVLDDQSGKKSINDKNVKKTMEEEDKDSEEEK-DDSYMKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQERFLHFNEICTTDYTEDNEREAETALAGEVEVDTDSNHGSQEEATQIELCVNQKDLNGQEEMIESAADNQKSPEDLDVKSANTESDLGILTSAPECPRDLNGAFLEERTSGELDIINGLKNLNLNAAVDPDEINIEILNDSHSPALKVYEVMNEDPETAFCTLANREAFSTDECSIQHCLYQFTRNEKLQDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLVSLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEESTRVLYSLYGVVEHSGTMRSGHYTAYAKERTASCHLSNLVLHGDIPQDCEMESTKGQWFHISDTHVQAVPITKVLNSQAYLLFYERIL