(        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440       450       460       470       480       490       500       510       520       530       540       550       560       570       580       590       600       610       620       630       640)
	|         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |         |
SAE2 human	MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQkKHVGRSKAQVAk K77-ac K77-ub ESVLQFYPkANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIk K152-ub K152-sm kGVtECyECHPk K164-ub K164-sm PTQRTFPGCtIRNTPSEPIHCIVWAkYLFNQLFGEEDADQEVsPDrADPEAAWEPTEAEARARAsNEDGDIk K236-ac K236-ub K236-sm RISTk K241-ac K241-ub EWAkSTGyDPVk K253-ac K253-ub K253-sm LFTk K257-ub K257-sm LFkDDIRYLLTMDk K271-ac K271-m1 K271-ub K271-sm LWRkRk K277-ub K277-sm PPVPLDWAEVQsQGEEtNASDQQNEPQLGLk K308-ub K308-sm DQQVLDVk K316-ub K316-sm K316-sc SYARLFSk K324-ac K324-ub SIEtLRVHLAEk K336-ac K336-ub GDGAELIWDkDDPSAMDFVTSAANLRMHIFSMNMkSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGkIDQCRTIFLNk K420-ub K420-sm QPNPRKkLLVPCALDPPNPNCYVCASKPEVTVRLNVHKVTVLTLQDkIVKEkFAMVAPDVQIEDGKGTILIssEEGETEANNHkkLsEFGIRNGSRLQADDFLQDYTLLINILHSEDLGkDVEFEVVGDAPEk K553-ub K553-sm VGPkQAEDAAKSITNGSDDGAQPStSTAQEQDDVLIVDsDEEDSsNNADVSEEERSRkRkLDEk K617-ac K617-ub K617-sm ENLsAk K623-ac K623-ub K623-sm RsRIEQkEELDDVIALD
SAE2 mouse	MALSrGLPrELAEAVsGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQkKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAkYLFNQLFGEEDADQEVsPDRADPEAAWEPTEAEARARAsNEDGDIKRISTKEWAkSTGYDPVkLFTkLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGE-ANAD-QQNEPQLGLKDQQVLDVKSYASLFSkSIETLRVHLAEkGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNkQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDkIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKkLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDsPEKVGPKQAEDAAKSIANGSDDGAQPsTStAQEQDDVLIVDsDEEGPSNSTDCSGDDKARKRKLEENEAAsTkKCRLEQMEDPDDVIALD
SAE2 rat	MSLSRGLPRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVsPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVkLFTKLFkDDIRYLLTMDkLWRKRKPPVPLDWAEVQSQGEEANAD-QQSEPQLGLKDQQVLDVKSYASLFSKsIETLRVRLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDtPEKVGPKQAEDAAKSIANGsDDGAQPSTSTAQEQDDVLIVDsDEEGPSNSADGSRDDRTRKRKLEENEGASTKKSRLEQVEDQDDVIALD
	*:*************:*******************************************************************:*:***:*:********************************************************************************************************************************************************************************************************::**:.**:******************:***********:*****************:****************************************************************************************:***************************************************************:****:*****************************************:****************:****************************::**::*.*.::::*****:*:*::*:*::*:**.*:.*******
Consensus	MALSRGLPRELAEAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFHPQANIEAHHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDADQEVSPDRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKPPVPLDWAEVQSQGEEANAD-QQNEPQLGLKDQQVLDVKSYASLFSKSIETLRVHLAEKGDGAELIWDKDDPPAMDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIDQCRTIFLNKQPNPRKKLLVPCALDPPNTNCYVCASKPEVTVRLNVHKVTVLTLQDKIVKEKFAMVAPDVQIEDGKGTILISSEEGETEANNPKKLSDFGIRNGSRLQADDFLQDYTLLINILHSEDLGKDVEFEVVGDAPEKVGPKQAEDAAKSIANGSDDGAQPSTSTAQEQDDVLIVDSDEEGPSNSADCSRDDRARKRKLEENEAASTKKSRLEQKEDQDDVIALD