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JADE3 human	-MKRHRPVSSSDSSDESPSTSFTSGSMYRIkSkIPNEHkkPAEVFRkDLISAMKLPDSHHINPDSYYLFADTWKEEWEkGVQVPAsPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSPDTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAEMGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTkTGTKWAHVSCALWIPEVSIACPERMEPITkISHIPPSRWALVCNLCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKtILDEGDEVkFKSYCLkHSQNRQk K371-ac K371-ub LGEAEYPHHRAkEQSQAkSEKTSLRAQKLRELEEEFYSLVRVEDVAAELGMPTLAVDFIYNyWKLKRKsNFNKPLFPPKEDEENGLVQPkEEsIHtRMRMFMHLRQDLERVRNLCYMISRREKLkLSHNKIQEQIFGLQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPKStPEDHRNsstEtDQQPHsPDSSSSVHSIRNMQVPQEsLEMRTKsYPRYPLESKNNRLLAsLsHSrSEAKESSPAWRtPssECYHGQsLGkPLVLQAALHGQSSIGNGkSQPNSKFAKSNGLEGsWSGNVTQKDSSSEMFCDQEPVFsPHLVsQGsFRkSTVEHFSRsFKETTNRWVkNTEDLQCyVk K735-ac K735-ub PTKNMsPKEQFWGRQVLRRSAGRAPYQENDGYCPDLELsDsEAEsDGNKEKVRVRKDssDRENPPHDSRRDCHGKSkTHPLSHSSMQR
JADE3 mouse	-MKRHRPVSSSESSDECPSTSFTSSsMyRKKSkNPkEQkKSAEVFRKDLISAMKIPDSHHVNPDSYYLFTDTWKEEWEKGVQVPANPDSVPTPSLRIISEKVKEMLFVRPRKYIRCSSPEsAEPGYINTLEQAASTCRYDLDDMDIFWLQELNEDLGEMGYGPIDETLMEKTIEVLERHCHENMNHAIETVEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKIPEGSWLCRSCVLGIYPQCVLCPKKGGAMKTTRTGTKWAHVSCALWIPEVSIACPERMEPVTKISHIPPSRWALVCNLCKLKTGACIQCSVKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSFCLKHSQNKPKLGDAEYHHHRVAEQSQAKSEKTSLRAQKLRELEEEFYTLVQVEDVAKEMELSAFTVDFIYNYWKLKRKSNFNKPLIPPKEEEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISrREKLKLSHTKVQEQIFGLQVQLINEEITEGLSLTNALENSLFYPPPRITLKLKMPKSTSEDCKDSSTETEHQLSsPGSSsPGHSKRsPQMPEEPLDMNVKIYPRYPLESKSNCLQTSRSHSRCETKSSsPTPRAPSAEFYHGQSLGKPLALQAALHGQVSIGNGKNQPNSRVSSSNGLEGNWSGNITQKVNSSEVCYDQESMLSSHLPSPGNIRKSSMEHFSRSFKEATNTWVKPTEDLQYCVKPTKNVSSKEQLWGRQLLRRPTGRASYQETDGYCPDLEPsDsEAEGEGSKETPRVKRESSDRENPSHDSARECHGKTKTHPHSHSSMQR
JADE3 rat	MMKRHRPVSSSESSDECPSTSFTSGSMYRKKSKNPKEHKKSAEVFRKDLISAMKIPDSHHINPDSYYLFTDTWKEEWEKGVQVPANPDSVPTPSLRIISEKVKEILFVRPRKYIRCSSPESAEPGYINTLELAASTCRYDLDDMDIFWLQELNEDLGEMGYGPIDETLMEKTIEVLERHCHENMNHAIETVEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKIPEGSWLCRSCVLGIYPQCVLCPKKGGAMKTTRTGTKWAHVSCALWIPEVSIACPERMEPVTKISHIPPSRWALVCNLCKLKTGACIQCSVKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSFCLKHSQNKPKLGDAEYHHHRAAEQSQAKSEKTSLRAQKLRELEEEFYTLVQVEDVAKEMGLSAFTVDFIYNYWKLKRKSNFNKPLIPPKEDEQNGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHTKVQEQIFGLQVQLINEEITDGLSLTNALENSLFYPPPRITLKLKMPKSTSEDCRDSSTETEHQPSSPGSSSPSHSKRSPEMPEEPLDMNVKIYPRYPLESKSNCVLASRSHSQSETRSSSPTQRAPSAEFYHGQTLGKPLALQAALHGQASIGNGKNQPNSRLASSNGLEGNWSGNITQKVNSGEMCYDQESMLSSHLPSSGNIRKSGMEHFSRSFKEATNTWVKPNEDLQYCVKPTKNVSSKEQLWGRPLLRRSTGRASYQETDGYCPDLEPSDSEAEGEGNKETVRVKRESSDRENPSHDSARECHGKTKTHPHSHSSMQR
	.**********:****:*******:****:***:*:*:**:*************:*****:********:***************:**:**:******:****:.**:******:****:::******::*:***:********************:***:**:**:*****:*****************:**********************************************:***************************:***:***************************:*****************************:*********************************:*******::***:***:***::*************************:**:*****:*:::::::********************:****:*:*********************************************:*:***********:*:**::**:**************************:**:::*****::*::**:***:.**:*::::*:*:*:*::*:*********:*::::*:***::*:::***:.*:**:*:****:*****:********:******:****:.::******:****:***::*:*:::***:::*:**:*.*::***.:*********:**:***::****::******:*:***:***::***::***:***:********:******::*:**::**:::*******:***:*:****:****:*******
Consensus	-MKRHRPVSSSESSDECPSTSFTSGSMYRKKSKNPKEHKKSAEVFRKDLISAMKIPDSHHINPDSYYLFTDTWKEEWEKGVQVPANPDSVPTPSLRIISEKVKEILFVRPRKYIRCSSPESAEPGYINTLELAASTCRYDLDDMDIFWLQELNEDLGEMGYGPIDETLMEKTIEVLERHCHENMNHAIETVEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGILKIPEGSWLCRSCVLGIYPQCVLCPKKGGAMKTTRTGTKWAHVSCALWIPEVSIACPERMEPVTKISHIPPSRWALVCNLCKLKTGACIQCSVKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSFCLKHSQNKPKLGDAEYHHHRAAEQSQAKSEKTSLRAQKLRELEEEFYTLVQVEDVAKEMGLSAFTVDFIYNYWKLKRKSNFNKPLIPPKEDEENGLVQPKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHTKVQEQIFGLQVQLINEEITAGLSLTNALENSLFYPPPRITLKLKMPKSTSEDCRDSSTETEHQPSSPGSSSPGHSKRSPQMPEEPLDMNVKIYPRYPLESKSNCLLASRSHSRSETKSSSPTQRAPSAEFYHGQSLGKPLALQAALHGQASIGNGKNQPNSRLASSNGLEGNWSGNITQKVNSSEMCYDQESMLSSHLPSQGNIRKSGMEHFSRSFKEATNTWVKPTEDLQYCVKPTKNVSSKEQLWGRQLLRRSTGRASYQETDGYCPDLEPSDSEAEGEGNKETVRVKRESSDRENPSHDSARECHGKTKTHPHSHSSMQR