Multiple Sequence Alignment:
Cezanne Download MSA
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Cezanne human MTLDMDAVLSDFVRSTGAEPGLARDLLEGkNWDVNAALSDFEQLRQVHAGNLPPsFSEGSGGSRtPEKGFSDREPtRPPRPILQRQDDIVQEkRLSRGIsHAsssIVSLARSHVSSNGGGGGSNEHPLEMPICAFQLPDLTVYNEDFRsFIERDLIEQsMLVALEQAGRLNWWVSVDPTSQRLLPLATTGDGNCLLHAASLGMWGFHDRDLMLRKALyALMEkGVEKEALKRRWRWQQTQQNKESGLVYTEDEWQkEWNELIkLASSEPRMHLGTNGANCGGVESSEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKENtkEQAVIPLTDSEYkLLPLHFAVDPGkGWEWGKDDSDNVRLASVILSLEVKLHLLHSYMNVKWIPLSSDAQAPLAQPEsPtAsAGDEPRstPEsGDsDKEsVGSSSTSNEGGRRKEKSKRDREKDKKRADsVANk
LGsFGkTLGSKLKKNMGGLMHSKGSkPGGVGTGLGGSSGTEtLEKKKK-NsLKSWKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGKFIFVGTLKMGHRHQYQEEMIQRYLsDAEERFLAEQkQKEAERKIMNGGIGGGPPPAKKPEPDAREEQPTGPPAESRAMAFSTGYPGDFTIPrPSGGGVHCQEPRRQLAGGPCVGGLPPYATFPRQCPPGRPYPHQDsIPSLEPGSHSKDGLHRGALLPPPYRVADSYSNGyREPPEPDGWAGGLRGLPPTQTKCKQPNCSFYGHPETNNFCSCCYREELRRREREPDGELLVHRF
Cezanne iso2 human MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDVNAALSDFEQLRQVHAGNLPPSFSEGSGGSRTPEKGFSDREPTRPPRPILQRQDDIVQEKRLSRGISHASSSIVSLARSHVSSNGGGGGSNEHPLEMPICAFQLPDLTVYNEDFRSFIERDLIEQSMLVALEQAGRLNWWVSVDPTSQRLLPLATTGDGNCLLHAASLGMWGFHDRDLMLRKALYALMEKGVEKEALKRRWRWQQTQQNKESGLVYTEDEWQKEWNELIKLASSEPRMHLGTNGANCGGVESSEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKENTKEQAVIPLTDSEYKLLPLHFAVDPGKGWEWGKDDSDNVRLASVILSLEVKLHLLHSYMNVKWIPLSSDAQAPLAQPESPTASAGDEPRSTPESGDSDKESVGSSSTSNEGGRRKEKSKRDREKDKKRADSVANKLGSFGKTLGSKLKKNMGGLMHSKGSKPGGVGTGLGGSSGTETLEKKKK-NSLKSWKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGKFIFVGTLKMGHRHQYQEEMIQRYLSDAEERFLAEQKQKEAERKIMNGGIGGGPPPAKKPEPDAREEQPTGPPAESRAMAFSTGYPGDFTIPRPSGGGVHCQEPRRQLAGGPCVGGLPPYATFPRQCPPGRPYPHQDSIPSLEPGSHSKDGLHRGALLPPPYRVADSYSNGYREPPEPDGWAGGLRGLPPTQTKCKQPDGELL-----------------------------VHRF
Cezanne mouse MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDVSAALSDFEQLRQVHAGNLsPPFSGGSTCPKTPEKGGSDREPTRPSRPILQRQDDVIQEkRLSRGIsHAssSIVsLARSHVSSNGGGGGSSEHPLEMPICAFQLPDLTVYKEDFRSFIERDLIEQSMLVALEQAGRLNWWVSMDSTCQRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYALMEKGVEKEALRRRWRWQQTQQNKESGLVYTEDEWQKEWNELIkLASSEPRMHLGSNGASGGGVESSEEPVYESLEEFHVFVLAHVLKRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKESAKEQAVIPLTDSEHKLLPLHFAVDPGKGWEWGKDDNDNVRLASIILSLEVKLHLLHSYMNVKWIPLSSDSQAPLAQPEsPtASAGDEPRSTPEsGEsDKEsVGsSSLGNEGSRRKEKSKRDREKDKKRADsVANKLGsFGkTLGSKLKKNMGGLMHSKGPKPGGLGSGSGISSGTETLEKKKKNNTLKSWKGGKEEAAGDGPVSEKPPSESVGNGGSKYSQEVMQSLSTMRIAMQGEGKYIFVGTLKMGHRHQYQEEMIQRYLADAEERFLAEQKQKEVERKIMNGGLVSGPPPAKKPEPDGGEDQPSDsPAEPKAMAFSTAyPGGFtIPRPSGGGVHCQEPRRQLAGGPCVGGLPSYAtFPRQYP-GRPYPHQDNIPALEPG---KDGVHRGALLPPQFRVADSySNGyREPPEPDGWAGAPRGLPPTQTKCKQPNCSFYGHPETNNLCSCCYREELRRREREPGGELLAHRF
Cezanne rat MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDVSAALSDFEQLRQVHAGNLSPPFSGGSTCPKTPEKGGSDREPTRPSRPILQRQDDIIQEKRLSRGIsHASSsIVSLARSHVSSNGGGGGSSEHPLEMPICAFQLPDLTVYKEDFRSFIERDLIEQSMLVALEQAGRLNWWVSVDSTCQRLLPLATTGDGNCLLHAASLGMWGFHDRDLVLRKALYALMEKGVEKEALKRRWRWQQTQQNKESGLVYTEDEWQKEWNELIKLASSEPRMHLGTNGASGGGVESSEEPVYESLEEFHVFVLAHVLKRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKDSAKEQAVIPLTDSEHKLLPLHFAVDPGKGWEWGKDDNDNVRLASVILSLEVKLHLLHSYMNVKWIPLSSESQAPLAQPESPTASAGDEPRSTPESGESDKESVGSSSISNEGSRRKEKSKRDREKDKKRADSVANkLGSFGKTLGSKLKKNMGGLMHSKGPKPGGLGSGSGISSGTETLEKKKKNNALKSWKGGkEEAAGDGPVSEKPTSEPVGNGGSKYSQEVMQSLSILRIAMQGEGKYIFVGTLKMGHRHQYQEEMIQRYLADAEERFLAEQKQKEAERKIMNGGLVSGPPPAKKPEPDGGEDQPSDSPAESKATGFSPGYPGGFTIPRPSGGGVHCQEPRRQLAGGPCVGGLPSYATFPRQYPPGRPYSHQDSIPSLEPG---KDGVHRGALLPPQFRVADSYSNGYREPPEPDGWAGAPRGLPPTQTKCKQPNCSFYGHPETNNFCSCCYREELRRREREPGGELLAHRF
  **********************************:*****************:*:**:**::::*****:********:*********::*********************************:*******************:*******************************:*:*:*******************************:******************:*******************************************:***::**************************:*************************************************************:::************:*********************:*******:************************::*************************:**********.:***:***********************************************:****:*:*:*:************.*:*********************::*:*****************::*:*******:***********************:**************:********:::***********::*:**:::***::*::**::***:******************************:*******:*:****:***:**:****...***:********::*********************::*************::::::::::::.::::::::::::::::.:::::***
Consensus MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDVNAALSDFEQLRQVHAGNLPPPFSEGSGCPRTPEKGGSDREPTRPPRPILQRQDDIIQEKRLSRGISHASSSIVSLARSHVSSNGGGGGSNEHPLEMPICAFQLPDLTVYNEDFRSFIERDLIEQSMLVALEQAGRLNWWVSVDPTCQRLLPLATTGDGNCLLHAASLGMWGFHDRDLMLRKALYALMEKGVEKEALKRRWRWQQTQQNKESGLVYTEDEWQKEWNELIKLASSEPRMHLGTNGANCGGVESSEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKENAKEQAVIPLTDSEHKLLPLHFAVDPGKGWEWGKDDNDNVRLASVILSLEVKLHLLHSYMNVKWIPLSSDAQAPLAQPESPTASAGDEPRSTPESGDSDKESVGSSSTSNEGGRRKEKSKRDREKDKKRADSVANKLGSFGKTLGSKLKKNMGGLMHSKGPKPGGLGSGLGGSSGTETLEKKKKNNSLKSWKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRIAMQGEGKFIFVGTLKMGHRHQYQEEMIQRYLADAEERFLAEQKQKEAERKIMNGGIGGGPPPAKKPEPDAREDQPSDPPAESRAMAFSTGYPGDFTIPRPSGGGVHCQEPRRQLAGGPCVGGLPPYATFPRQCPPGRPYPHQDSIPSLEPGSHSKDGLHRGALLPPQFRVADSYSNGYREPPEPDGWAGALRGLPPTQTKCKQPNCSFYGHPETNNFCSCCYREELRRREREPGGELLAHRF
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.