Multiple Sequence Alignment:
Mena Download MSA
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Mena human --------------------MSEQSICQARAAVMVyDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLkYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------TGPtLPRQNsQLPAQVQNGPsQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERER----QERERQEQLEREQLEWERERRIssA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP-PPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVsRMEDtSFPsGGNAIGVNsAssKTDTGRGNGPLPLGGsGLMEEMSALLARRRRIAEk
GstIETEQKEDKGEDsEPVtSkAsststPEPtRKPWERtNtMNGsKsPVIsRRDsPRKNQIVFDNrsyDsLHRPksTPLSQPsANGVQTEGLDYDRLkQDILDEMRKELTKLkEELIDAIRQELSKSNTA
Mena iso2 human --------------------MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------TGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERER----QERERQEQLEREQLEWERERRIssA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP-PPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTStPEPTRKPWERtNtMNGsKsPVIs---------------------RPKSTPLSQPSANGVQTEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQELSKSNTA
Mena iso3 human --------------------MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------TGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERER----QERERQEQLEREQLEWERERRISS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP-PPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTRKPWERtNTMNGsKsPVIs---------------------RPKSTPLSQPSANGVQTEGLDYDRLKQDILDEMRKELTKLKEELIDAIRQELSKSNTA
Mena mouse --------------------MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLkYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQEAAQSKVTATQDSTNLRCIFCGPTLPRQNsQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMERERLERER-----LERERLERERLEQEQLERQRQEREHVERLER--------------------------ERLERLERERQER--ERERLEQLEREQVEWERERRMsNAAPSSDSSLSSAPLPEYSSCQPPSAPPPSYAKVISAPVSDATPDYAVVTALPPTSTPPtPPLRHAATRFAtsLGSAFHPVLPHYATVPRPLNKNsRPssPVNTPSsQPPAAKSCAWPTSNFSPLPPsPPIMISsPPGKATGPRPVLPVCVSSPVPQMPPSPTAPNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPPLPPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAGAPASAETPLNPELGDSSASEPGLQAASQPAESPTPQGLVLGPPAPPPPPPLPSGPAYAS-ALPPPPGPPPPPPLPSTGPPPPPPPPPPLPNQAPPPPPPPPAPPLPASGIFSGSTSEDNRPLTGLAAAIAGAKLRKVsRVEDGSFPGGGNTGSVSLASSKADAGrGNGPLPLGGSGLMEEMSALLARRRRIAEKGStIETEQKEDRNEDAEPITAKAPStstPEPTRKPWERtNtMNGsKsPVIs---------------------RPKSTPSSQPSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA
Mena iso3 mouse --------------------MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------AGPTLPRQNsQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMERERLERER-----LERERLERERLEQEQLERQRQEREHVERLER--------------------------ERLERLERERQER--ERERLEQLEREQVEWERERRMSNAA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APASAETPLNPELGDSSASEPGLQAASQPAESPTPQGLVLGPPAPPPPPPLPSGPAyAS-ALPPPPGPPPPPPLPSTGPPPPPPPPPPLPNQAPPPPPPPPAPPLPASGIFSGSTSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPGGGNTGSVSLASSKADAGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDRNEDAEPITAKAPSTSTPEPTRKPWERTNTMNGSKSPVIS---------------------RPKSTPSSQPSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA
Mena iso4 mouse --------------------MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------AGPTLPRQNsQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMERERLERER-----LERERLERERLEQEQLERQRQEREHVERLER--------------------------ERLERLERERQER--ERERLEQLEREQVEWERERRMsNAAPSSDSSLSSAPLPEYSSCQPPSAPPPSYAKVISAPVSDATPDYAVVTALPPTSTPPTPPLRHAATRFATSLGSAFHPVLPHYATVPRPLNKNSRPSSPVNTPSSQPPAAKSCAWPTSNFSPLPPSPPIMISSPPGKATGPRPVLPVCVSSPVPQMPPSPTAPNGSLDSVTYPVSPPPTSGPAAPPPPPPPPPPPPPPPLPPPPLPPLASLSHCGSQASPPPGTPLASTPSSKPSVLPSPSAGAPASAETPLNPELGDSSASEPGLQAASQPAESPTPQGLVLGPPAPPPPPPLPSGPAYAS-ALPPPPGPPPPPPLPSTGPPPPPPPPPPLPNQAPPPPPPPPAPPLPASGIFSGSTSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPGGGNTGSVSLASSKADAGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDRNEDAEPITAKAPSTSTPEPTRKPWERTNTMNGSKSPVIS---------------------RPKSTPSSQPSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA
Mena rat MDVEFVSYSIPkLRSSQSLRISEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLkYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------AGPTLPRQNSQLPAQVQNGPSQEEMEIQRRQLQEQQRQKELERERMERERLERER-----LERERLERERLEQEQLERQRQEREHVERLER--------------------------ERLERLERERQDRERERERLEQLEREQVEWERERRMSNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHVLGPPAPPPPPPLPSGPAYAS-ALPPPPGPPPPPPLPSAGPPPPPPPPPPLPNQVPPPPPPPPAPPLPASGIFSGSMSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPSGGNTVSVNLASSKTDSGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDRSEDAEPVtsKAASTSTPEPTRKPWERTNTMNGSKsPVIS---------------------RPKSTPSSQPSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA
                      :******************************************************************************************************************                   :***********************:********************:****:****.....******************:*****::*****..........................**********... .****:*******:*******:*::.                                                                                                                                                                                                                                                 .::::.:::::..:::::::::::::::::::.:..:*:****:*********:***:**.****************:*****.*********:****************:*::*:************************:**:***:***:::*::****:*:******************************************::**:**:*:**:***************************                     ******:******************************:********************
Consensus --------------------MSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASAMMHALEVLNSQE-------------------AGPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERMERERLERER-----LERERLERERLEQEQLERQRQEREHVERLER--------------------------ERLERLERERQER-QERERLEQLEREQVEWERERRMSNA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APASAETPLNPELGDSSASEPGLQAASQPAESPTPQGIVLGPPAPPPPPPLPSGPAYAS-ALPPPPGPPPPPPLPSTGPPPPPPPPPPLPNQVPPPPPPPPAPPLPASGIFSGSMSEDNRPLTGLAAAIAGAKLRKVSRVEDGSFPSGGNTGSVNLASSKTDAGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDRNEDAEPVTSKAPSTSTPEPTRKPWERTNTMNGSKSPVIS---------------------RPKSTPSSQPSANGVQTEGLDYDRLKQDILDEMRKELAKLKEELIDAIRQELSKSNTA
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.