Multiple Sequence Alignment:
DBNL Download MSA
  (        10        20        30        40        50        60        70        80        90       100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260       270       280       290       300       310       320       330       340       350       360       370       380       390       400       410       420       430       440  )
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DBNL human MAANLsRNGPALQEAyVRVVtEksPtDWALFTYEGNSNDIRVAGtGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPkFVLINWTGEGVNDVRKGACAsHVSTMAsFLKGAHVtINARAEEDVEPECIMEkVAkAsGANysFHkEsGRFQDVGPQAPVGsVyQktNAVsEIkRVGkDsFWAKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRyQEQGGEAs---PQ-RtWEQQQEVVsRNRNEQ--------ESAVHPREIFKQKERAMsttsIssPQPGkLrsPFLQkQLtQPEtHFGREPAAAIsRPRADLPAEEPAPstPPCLVQAEEEAVyEEPPEQETFyEQPPLVQQQGAGSEHIDHHIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
DBNL iso2 human MAANLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIMEKVAKASGANySFHKESGRFQDVGPQAPVGSVyQKTNAVSEIKRVGKDSFWAKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRyQEQGGEAs---PQsRTWEQQQEVVSRNRNEQ--------ESAVHPREIFKQKERAMsttsIssPQPGKLRsPFLQKQLtQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEAVyEEPPEQETFyEQPPLVQQQGAGSEHIDHHIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
DBNL iso3 human MAANLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACASHVSTMASFLKGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKESGRFQDVGPQAPVGSVYQKTNAVSEIKRVGKDSFWAKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRyQEQGGEAs---PQsRTWEQQQEVVSRNRNEQGSTCAsLQESAVHPREIFKQKERAMSTTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPLVQQQGAGSEHIDHHIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
DBNL mouse MAVNLSRNGPALQEAYVRVVTEKSPtDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIMEKVAKASGANysFHKESTSFQDVGPQAPVGsVyQKTNAIsEIKRVGKDNFWAKAEKEEENRRLEEKRRAEEERQRLEEERRERELQEAARREQRyQEQHRSAGAPSPSSRTGEPEQEAVSRTRQEWE----SAGQQAPHPREIFKQKERAMstTsVTSSQPGKLRsPFLQKQLtQPETSYGREPTAPVSRPAAGVC-EEPAPSTL-SSAQTEEEPTyEVPPEQDTLyEEPPLVQQQGAGsEHIDNyMQSQGFSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
DBNL rat MAVNLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMYAFCRVkDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKESSCFQDVGPQAPVGSVYQKTNAVSEIKRVGkDNFWAKAEKEEENRRLEEKRRAEEEKQRLEEERRERELQEAARREQRYQEQHRSAGPPsPSSRTGELEQEVVSRSRQEWE----SAGQQAPHPREIFKQKERAMsTTsVSSSQPGkLRsPFLQKQFtQPEASYGREPTsPVSRPAAGVC-EELAPSTP-PSAQTDDEPTYEVPSEQETLYEEPPPVQQPGAGSGHIDNYMQSQDLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
DBNL cow MAVNLSRNGPALLEAYQQVVNEKSSTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMAGFLKGAHVTINARAEEDVEPECIMQKVARASGANYTFHKESSRFQDTGPQAPVGSVYQKTNAVSEIKRVGKDSFWAKAEKEEENRRLEEKRRAEEERQQLEQERRERELREAALREQRYQEQGGEAG---LQRK-YE-QHEVLSRNRE----------EQPAHPREIFKQKERAMsTTSISSPQPGKLKSPFLQKQLtQPDTPISRESPHATSRPRADLR-EEPVPSIPPCSVQVEEEAVYEEPPEQETFYEEPPAVQQQDASSEPIDHY---PGLSGKGLCARALYDYQAADETEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
  **:*********:***::**:***:***************************:*********************************************:******:***********************:***:******:*****::***:***************:*********:**********************::::**:*******:***:********:::*: ..::::::*.::*::**:*::..    ...::::*****************::*:*****:*******:***:::::**:::::***:*:::.**::**::::::*:::*::**:*:**:*:**:**:***::*:*::**::.:.:::**:**************:*******************************************
Consensus MAANLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEEMVEELNSGKVMYAFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMASFLKGAHVTINARAEEDVEPECIMEKVAKASGANYSFHKESGRFQDVGPQAPVGSVYQKTNAVSEIKRVGKDSFWAKAEKEEENRRLEEKRRAEEAQRQLEQERRERELREAARREQRYQEQGGEAG---PQSRTWEQQQEVVSRNRNEQ-----S--EQAVHPREIFKQKERAMSTTSISSPQPGKLRSPFLQKQLTQPETHFGREPAAAISRPRADLPAEEPAPSTPPCLVQAEEEAVYEEPPEQETFYEQPPLVQQQGAGSEHIDHHIQGQGLSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE
Modified residues are boxed in RED. Mouse-over modified sites to view residue numbers.
Aligned using Clustal Omega. Conservation and consensus calculated using von Neumann entropy from PFAAT.